Abstract B005: Tolerance to colibactin correlates with response to chemotherapeutic agents in colorectal cancer
Sogari, Alberto, Rovera, Emanuele, Reilly, Nicole Megan, Lamba, Simona, Durinikova, Erika, Lorenzato, Annalisa, Avolio, Marco, Piumatti, Eleonora, Russo, Mariangela, Arena, Sabrina, Trusolino, Livio, Donalisio, Manuela, Nicolantonio, Federica Di, Lembo, David, Bardelli, Alberto
Published in Cancer research (Chicago, Ill.) (09.01.2024)
Published in Cancer research (Chicago, Ill.) (09.01.2024)
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Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
Sogari, Alberto, Rovera, Emanuele, Grasso, Gaia, Mariella, Elisa, Reilly, Nicole Megan, Lamba, Simona, Mauri, Gianluca, Durinikova, Erika, Vitiello, Pietro Paolo, Lorenzato, Annalisa, Avolio, Marco, Piumatti, Eleonora, Bonoldi, Emanuela, Aquilano, Maria Costanza, Arena, Sabrina, Sartore-Bianchi, Andrea, Siena, Salvatore, Trusolino, Livio, Donalisio, Manuela, Russo, Mariangela, Di Nicolantonio, Federica, Lembo, David, Bardelli, Alberto
Published in Cell reports. Medicine (20.02.2024)
Published in Cell reports. Medicine (20.02.2024)
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Abstract 6011: Pharmacological inhibition of PMS2 increases tumor mutational burden, induces microsatellite instability and elicits immune mediated rejection in vivo
Piumatti, Eleonora, Hervieu, Alexia, Riou, Philippe, Blagg, Julian, Peall, Adam, Weeks, Sam, Rodríguez-Plata, Maria T., Rospo, Giuseppe, Arunachalam, Sasi, Meier, Bettina, Tongue, Paige, McLaren, Tessa, Parmar, Kalpesh, Patel, Pradip, Clark, David, Langley, Gareth, Nichols, Charles, Rousseau, Benoît, Winship, Paul, Baker, Matthew, Drysdale, Martin, Germano, Giovanni, Bardelli, Alberto
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Abstract C086: NP1867, a potent, selective, covalent small molecule inhibitor of DNA Mismatch Repair (MMR) protein PMS2, functionally inhibits MMR in cells and elicits COSMIC mutational signatures consistent with MMR-deficient patient samples
Blagg, Julian, Riou, Philippe, Hervieu, Alexia, Piumatti, Eleonora, Rospo, Giuseppe, Arunachalam, Sasi, Meier, Bettina, Weeks, Sam, Rodriguez, Maria, Parmar, Kalpesh, Patel, Pradip, Peall, Adam, Tongue, Paige, McLaren, Tess, Workman, Robert, Bago, Ruzica, Robjohns, Stuart, Beaumont, Rebecca, Briggs, Mike, Langley, Gareth, Nichols, Charles, Clark, David, Winship, Paul, Rousseau, Benoit, Baker, Matthew, Drysdale, Martin, Germano, Giovanni, Bardelli, Alberto
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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