Synthesis and biological characterization of L-N(6)-(1-iminoethyl)lysine 5-tetrazole-amide, a prodrug of a selective iNOS inhibitor
Hallinan, E Ann, Tsymbalov, Sofya, Dorn, Clifford R, Pitzele, Barnett S, Hansen, Jr, Donald W, Moore, William M, Jerome, Gina M, Connor, Jane R, Branson, Linda F, Widomski, Deborah L, Zhang, Yan, Currie, Mark G, Manning, Pamela T
Published in Journal of medicinal chemistry (11.04.2002)
Published in Journal of medicinal chemistry (11.04.2002)
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4-Fluorinated L-lysine analogs as selective i-NOS inhibitors: methodology for introducing fluorine into the lysine side chain
Hallinan, EA, Kramer, SW, Houdek, SC, Moore, WM, Jerome, GM, Spangler, DP, Stevens, AM, Shieh, HS, Manning, PT, Pitzele, BS
Published in Organic & biomolecular chemistry (21.10.2003)
Published in Organic & biomolecular chemistry (21.10.2003)
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5-Fluorinated l-Lysine Analogues as Selective Induced Nitric Oxide Synthase Inhibitors
Hallinan, E. Ann, Hagen, Timothy J, Bergmanis, Arija, Moore, William M, Jerome, Gina M, Spangler, Dale P, Stevens, Anna M, Shieh, Huey S, Manning, Pamela T, Pitzele, Barnett S
Published in Journal of medicinal chemistry (12.02.2004)
Published in Journal of medicinal chemistry (12.02.2004)
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3-Hydroxy-4-methyl-5-pentyl-2-iminopyrrolidine: A potent and highly selective inducible nitric oxide synthase inhibitor
Tsymbalov, Sofya, Hagen, Timothy J., Moore, William M., Jerome, Gina M., Connor, Jane R., Manning, Pamela T., Pitzele, Barnett S., Hallinan, E.Ann
Published in Bioorganic & medicinal chemistry letters (18.11.2002)
Published in Bioorganic & medicinal chemistry letters (18.11.2002)
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2-Iminopyrrolidines as Potent and Selective Inhibitors of Human Inducible Nitric Oxide Synthase
Hagen, Timothy J, Bergmanis, Arija A, Kramer, Steven W, Fok, Kam F, Schmelzer, Albert E, Pitzele, Barnett S, Swenton, Lydia, Jerome, Gina M, Kornmeier, Christine M, Moore, William M, Branson, Linda F, Connor, Jane R, Manning, Pamela T, Currie, Mark G, Hallinan, E. Ann
Published in Journal of medicinal chemistry (10.09.1998)
Published in Journal of medicinal chemistry (10.09.1998)
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Selective heterocyclic amidine inhibitors of human inducible nitric oxide synthase
Moormann, Alan E, Metz, Sue, Toth, Mihaly V, Moore, William M, Jerome, Gina, Kornmeier, Christine, Manning, Pamela, Hansen, Donald W, Pitzele, Barnett S, Webber, R.K
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
Published in Bioorganic & medicinal chemistry letters (08.10.2001)
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Substituted 2-Iminopiperidines as Inhibitors of Human Nitric Oxide Synthase Isoforms
Webber, R. Keith, Metz, Suzanne, Moore, William M, Connor, Jane R, Currie, Mark G, Fok, Kam F, Hagen, Timothy J, Hansen, Donald W, Jerome, Gina M, Manning, Pamela T, Pitzele, Barnett S, Toth, Mihaly V, Trivedi, Mahima, Zupec, Mark E, Tjoeng, F. Siong
Published in Journal of medicinal chemistry (01.01.1998)
Published in Journal of medicinal chemistry (01.01.1998)
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Synthesis and Biological Characterization of L-N6-(1-Iminoethyl)lysine 5-Tetrazole-amide, a Prodrug of a Selective iNOS Inhibitor
Hallinan, E. Ann, Tsymbalov, Sofya, Dorn, Clifford R, Pitzele, Barnett S, Hansen, Donald W, Moore, William M, Jerome, Gina M, Connor, Jane R, Branson, Linda F, Widomski, Deborah L, Zhang, Yan, Currie, Mark G, Manning, Pamela T
Published in Journal of medicinal chemistry (11.04.2002)
Published in Journal of medicinal chemistry (11.04.2002)
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Acetamidine Lysine Derivative, N-(5(S)-amino-6,7-dihydroxyheptyl)ethanimidamide Dihydrochloride: A Highly Selective Inhibitor of Human Inducible Nitric Oxide Synthase
Hallinan, E. Ann, Tsymbalov, Sofya, Finnegan, Patricia M, Moore, William M, Jerome, Gina M, Currie, Mark G, Pitzele, Barnett S
Published in Journal of medicinal chemistry (12.03.1998)
Published in Journal of medicinal chemistry (12.03.1998)
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2-Iminohomopiperidinium Salts as Selective Inhibitors of Inducible Nitric Oxide Synthase (iNOS)
Hansen, Donald W, Peterson, Karen B, Trivedi, Mahima, Kramer, Steven W, Webber, Ronald K, Tjoeng, Foe S, Moore, William M, Jerome, Gina M, Kornmeier, Christine M, Manning, Pamela T, Connor, Jane R, Misko, Thomas P, Currie, Mark G, Pitzele, Barnett S
Published in Journal of medicinal chemistry (23.04.1998)
Published in Journal of medicinal chemistry (23.04.1998)
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Enkephalin Analogs as Systemically Active Antinociceptive Agents: O- and N-Alkylated Derivatives of the Dipeptide Amide L-2,6-Dimethyltyrosyl-N-(3-phenylpropyl)-D-alaninamide
Pitzele, Barnett S, Hamilton, Robert W, Kudla, Kathleen D, Tsymbalov, Sofya, Stapelfeld, Awilda, Savage, Michael A, Clare, Michael, Hammond, Donna L, Hansen, Donald W
Published in Journal of medicinal chemistry (01.04.1994)
Published in Journal of medicinal chemistry (01.04.1994)
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Potential antisecretory antidiarrheals. 2. .alpha.2-Adrenergic 2-[(aryloxy)alkyl]imidazolines
Moormann, Alan E, Pitzele, Barnett S, Jones, P. H, Gullikson, Gary W, Albin, David, Yu, Stella S, Bianchi, Robert G, Sanguinetti, Elizabeth L, Rubin, Barbara
Published in Journal of medicinal chemistry (01.02.1990)
Published in Journal of medicinal chemistry (01.02.1990)
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Potential antisecretory antidiarrheals. 1. .alpha.2-Adrenergic aromatic aminoguanidine hydrazones
Pitzele, Barnett S, Moormann, Alan E, Gullikson, Gary W, Albin, David, Bianchi, Robert G, Palicharla, Prima, Sanguinetti, Elizabeth L, Walters, D. Eric
Published in Journal of medicinal chemistry (01.01.1988)
Published in Journal of medicinal chemistry (01.01.1988)
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gamma.-Alkylation of 2-butynoic acid. Route to controlled prenol homologation
Pitzele, Barnett S, Baran, John S, Steinman, Douglas H
Published in Journal of organic chemistry (01.01.1975)
Published in Journal of organic chemistry (01.01.1975)
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Synthesis and biological activities of substituted glycyrrhetic acids
Baran, John S, Langford, Donna D, Liang, Chi D, Pitzele, Barnett S
Published in Journal of medicinal chemistry (01.02.1974)
Published in Journal of medicinal chemistry (01.02.1974)
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