Crystal Structure Analysis of Deamino-Oxytocin: Conformational Flexibility and Receptor Binding
Wood, S. P., Tickle, I. J., Treharne, A. M., Pitts, J. E., Mascarenhas, Y., Li, J. Y., Husain, J., Cooper, S., Blundell, T. L., Hruby, V. J., Buku, A., Fischman, A. J., Wyssbrod, H. R.
Published in Science (American Association for the Advancement of Science) (02.05.1986)
Published in Science (American Association for the Advancement of Science) (02.05.1986)
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Journal Article
Multidisciplinary cycles for protein engineering: site-directed mutagenesis and X-ray structural studies of aspartic proteinases
Pitts, J E, Dhanaraj, V, Dealwis, C G, Mantafounis, D, Nugent, P, Orprayoon, P, Cooper, J B, Newman, M, Blundell, T L
Published in Scandinavian journal of clinical & laboratory investigation. Supplement (1992)
Published in Scandinavian journal of clinical & laboratory investigation. Supplement (1992)
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Journal Article
Mutagenesis, biochemical characterization and X-ray structural analysis of point mutants of bovine chymosin
Williams, M G, Wilsher, J, Nugent, P, Mills, A, Dhanaraj, V, Fabry, M, Sedlácek, J, Uusitalo, J M, Penttila, M E, Pitts, J E, Blundell, T L
Published in Protein engineering (01.09.1997)
Published in Protein engineering (01.09.1997)
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Journal Article
Protein engineering of chymosin and expression in Trichoderma reesei
Pitts, J.E, Quinn, D, Uusitalo, J, Penttila, M
Published in Biochemical Society transactions (01.08.1991)
Published in Biochemical Society transactions (01.08.1991)
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Protein engineering loops in aspartic proteinases: site-directed mutagenesis, biochemical characterization and X-ray analysis of chymosin with a replaced loop from rhizopuspepsin
Nugent, P.G., Albert, A., Orprayoon, P., Wilsher, J., Pitts, J.E., Blundell, T.L., Dhanaraj, V.
Published in Protein engineering (01.10.1996)
Published in Protein engineering (01.10.1996)
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Journal Article
The Conformation of Deamino-Oxytocin: X-Ray Analysis of the 'Dry' and 'Wet' Forms
Husain, J, Blundell, T L, Cooper, S, Pitts, J E, Tickle, I J, Wood, S P, Hruby, V J, Buku, A, Fischman, A J, Wyssbrod, H R
Published in Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences (27.04.1990)
Published in Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences (27.04.1990)
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Journal Article
Adaptation of plasminogen activator sequences to known protease structures
Straßburger, W., Wollmer, A., Pitts, J.E., Glover, I.D., Tickle, I.J., Blundell, T.L., Steffens, G.J., Günzler, W.A., Ötting, F., Flohé, L.
Published in FEBS letters (04.07.1983)
Published in FEBS letters (04.07.1983)
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Journal Article
Protein Engineering and Design
Blundell, T L, Elliott, G, Gardner, S P, Hubbard, T, Islam, S, Johnson, M, Mantafounis, D, Murray-Rust, P, Overington, J, Pitts, J E
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (31.08.1989)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (31.08.1989)
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Journal Article
Modifying the substrate specificity of chymosin
Quinn, D, Pitts, J E, Mantafounis, D, Lawler, S E, Uusitalo, J, Penttilä, M, Strop, P
Published in Biochemical Society transactions (01.08.1991)
Published in Biochemical Society transactions (01.08.1991)
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Journal Article
A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure
Groves, M R, Dhanaraj, V, Badasso, M, Nugent, P, Pitts, J E, Hoover, D J, Blundell, T L
Published in Protein engineering (01.10.1998)
Published in Protein engineering (01.10.1998)
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Journal Article
Coypu insulin. Primary structure, conformation and biological properties of a hystricomorph rodent insulin
Bajaj, M, Blundell, T L, Horuk, R, Pitts, J E, Wood, S P, Gowan, L K, Schwabe, C, Wollmer, A, Gliemann, J, Gammeltoft, S
Published in Biochemical journal (01.09.1986)
Published in Biochemical journal (01.09.1986)
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Journal Article
The crystal structures of three non-pancreatic human insulins
Chawdhury, S A, Dodson, E J, Dodson, G G, Reynolds, C D, Tolley, S P, Blundell, T L, Cleasby, A, Pitts, J E, Tickle, I J, Wood, S P
Published in Diabetologia (01.12.1983)
Published in Diabetologia (01.12.1983)
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Journal Article
Conformational studies on the pancreatic polypeptide hormone family
GLOVER, Ian D., BARLOW, David J., PITTS, James E., WOOD, Stephen P., TICKLE, Ian J., BLUNDELL, Thomas L., TATEMOTO, Kazuhiko, KIMMEL, Joe R., WOLLMER, Axel, STRASSBURGER, Wolfgang, ZHANG, You‐Shang
Published in European journal of biochemistry (01.01.1984)
Published in European journal of biochemistry (01.01.1984)
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Journal Article
Excretion, Distribution, and Metabolism of Doxapram Hydrochloride
Bruce, Robert B, Pitts, J. E, Pinchbeck, Franklin, Newman, Jack
Published in Journal of medicinal chemistry (01.03.1965)
Published in Journal of medicinal chemistry (01.03.1965)
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