Influence of substitution at the 5α-Position on the side chain conformation of glucopyranosides
Rajasekaran, Parasuraman, Pirrone, Michael G., Crich, David
Published in Carbohydrate research (01.02.2021)
Published in Carbohydrate research (01.02.2021)
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Predictive Analysis of the Side Chain Conformation of the Higher Carbon Sugars: Application to the Preorganization of the Aminoglycoside Ring 1 Side Chain for Binding to the Bacterial Ribosomal Decoding A Site
Pirrone, Michael G, Gysin, Marina, Haldimann, Klara, Hobbie, Sven N, Vasella, Andrea, Crich, David
Published in Journal of organic chemistry (18.12.2020)
Published in Journal of organic chemistry (18.12.2020)
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Stereospecific synthesis of methyl 2-amino-2,4-dideoxy-6S-deuterio-α-D-xylo-hexopyranoside and methyl 2-amino-2,4-dideoxy-6S-deuterio-4-propyl-α-d-glucopyranoside: Side chain conformation of the novel aminoglycoside antibiotic propylamycin
Pirrone, Michael G., Matsushita, Takahiko, Vasella, Andrea, Crich, David
Published in Carbohydrate research (01.05.2020)
Published in Carbohydrate research (01.05.2020)
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Use of hydroxylamines, hydroxamic acids, oximes and amines as nucleophiles in the Zbiral oxidative deamination of N-acetyl neuraminic acid. Isolation and characterization of novel mono- and disubstitution products
Hawsawi, Mohammed, Pirrone, Michael G., Wickramasinghe, Anura, Crich, David
Published in Carbohydrate research (01.04.2020)
Published in Carbohydrate research (01.04.2020)
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Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens
Matsushita, Takahiko, Sati, Girish C, Kondasinghe, Nuwan, Pirrone, Michael G, Kato, Takayuki, Waduge, Prabuddha, Kumar, Harshitha Santhosh, Sanchon, Adrian Cortes, Dobosz-Bartoszek, Malgorzata, Shcherbakov, Dimitri, Juhas, Mario, Hobbie, Sven N, Schrepfer, Thomas, Chow, Christine S, Polikanov, Yury S, Schacht, Jochen, Vasella, Andrea, Böttger, Erik C, Crich, David
Published in Journal of the American Chemical Society (27.03.2019)
Published in Journal of the American Chemical Society (27.03.2019)
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Contrast‐enhanced μCT of the intervertebral disc: A comparison of anionic and cationic contrast agents for biochemical and morphological characterization
Newton, Michael D., Hartner, Samantha E., Timmons, Shannon, Delaney, Nathan D., Pirrone, Michael G., Baker, Kevin C., Maerz, Tristan
Published in Journal of orthopaedic research (01.05.2017)
Published in Journal of orthopaedic research (01.05.2017)
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Synthesis of saccharocin from apramycin and evaluation of its ribosomal selectivity
Sarpe, Vikram A., Pirrone, Michael G., Haldimann, Klara, Hobbie, Sven N., Vasella, Andrea, Crich, David
Published in MedChemComm (01.04.2019)
Published in MedChemComm (01.04.2019)
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Journal Article
Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses
Freitas, Brendan T, Ahiadorme, Daniil A, Bagul, Rahul S, Durie, Ian A, Ghosh, Samir, Hill, Jarvis, Kramer, Naomi E, Murray, Jackelyn, O’Boyle, Brady M, Onobun, Emmanuel, Pirrone, Michael G, Shepard, Justin D, Enos, Suzanne, Subedi, Yagya P, Upadhyaya, Kapil, Tripp, Ralph A, Cummings, Brian S, Crich, David, Pegan, Scott D
Published in ACS infectious diseases (11.03.2022)
Published in ACS infectious diseases (11.03.2022)
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Journal Article
Stereospecific synthesis of methyl 2-amino-2,4-dideoxy-6 S -deuterio-?-D- xylo -hexopyranoside and methyl 2-amino-2,4-dideoxy-6 S -deuterio-4-propyl- ?- D -glucopyranoside: Side chain conformation of the novel aminoglycoside antibiotic propylamycin
Pirrone, Michael G., Matsushita, Takahiko, Vasella, Andrea, Crich, David
Published in Carbohydrate research (01.05.2020)
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Published in Carbohydrate research (01.05.2020)
Journal Article
Contrast-enhanced μCT of the intervertebral disc: A comparison of anionic and cationic contrast agents for biochemical and morphological characterization: CONTRAST-ENHANCED μCT OF THE IVD
Newton, Michael D., Hartner, Samantha E., Timmons, Shannon, Delaney, Nathan D., Pirrone, Michael G., Baker, Kevin C., Maerz, Tristan
Published in Journal of orthopaedic research (01.05.2017)
Published in Journal of orthopaedic research (01.05.2017)
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Journal Article
Synthesis of saccharocin from apramycin and evaluation of its ribosomal selectivityElectronic supplementary information (ESI) available: Complete experimental parts, characterization, and copies of NMR spectra. See DOI: 10.1039/c9md00093c
Sarpe, Vikram A, Pirrone, Michael G, Haldimann, Klara, Hobbie, Sven N, Vasella, Andrea, Crich, David
Year of Publication 17.04.2019
Year of Publication 17.04.2019
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Synthesis of saccharocin from apramycin and evaluation of its ribosomal selectivity† †Electronic supplementary information (ESI) available: Complete experimental parts, characterization, and copies of NMR spectra. See DOI: 10.1039/c9md00093c
Sarpe, Vikram A., Pirrone, Michael G., Haldimann, Klara, Hobbie, Sven N., Vasella, Andrea, Crich, David
Published in MedChemComm (13.03.2019)
Published in MedChemComm (13.03.2019)
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Journal Article
Exploring noncovalent protease inhibitors for the treatment of SARS and SARS-like coronaviruses
Freitas, Brendan T., Ahiadorme, Daniil A., Bagul, Rahul S., Durie, Ian A., Ghosh, Samir, Hill, Jarvis, Kramer, Naomi E., Murray, Jackelyn, O’Boyle, Brady M., Onobun, Emmanuel, Pirrone, Michael G., Shepard, Justin D., Enos, Suzanne, Subedi, Yagya P., Upadhyaya, Kapil, Tripp, Ralph A., Cummings, Brian S., Crich, David, Pegan, Scott D.
Published in ACS infectious diseases (24.02.2022)
Published in ACS infectious diseases (24.02.2022)
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Journal Article
NEOMYCIN AND PAROMOMYCIN DERIVATIVES
VASELLA, Andrea, YANG, Guanyu, KATO, Takayuki, BOTTGER, Erik C, SONOUSI, Amr, MANDHAPATI, Appi Reddy, SARPE, Vikram, CRICH, David, SATI, Girish, HOBBIE, Sven N, PIRRONE, Michael G
Year of Publication 15.04.2021
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Year of Publication 15.04.2021
Patent
NEOMYCIN AND PAROMOMYCIN DERIVATIVES
VASELLA, Andrea, YANG, Guanyu, KATO, Takayuki, BOTTGER, Erik C, SONOUSI, Amr, MANDHAPATI, Appi Reddy, SARPE, Vikram, CRICH, David, SATI, Girish, HOBBIE, Sven N, PIRRONE, Michael G
Year of Publication 11.10.2018
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Year of Publication 11.10.2018
Patent