Metabolic targeting of cancer associated fibroblasts overcomes T-cell exclusion and chemoresistance in soft-tissue sarcomas
Broz, Marina T., Ko, Emily Y., Ishaya, Kristin, Xiao, Jinfen, De Simone, Marco, Hoi, Xen Ping, Piras, Roberta, Gala, Basia, Tessaro, Fernando H. G., Karlstaedt, Anja, Orsulic, Sandra, Lund, Amanda W., Chan, Keith Syson, Guarnerio, Jlenia
Published in Nature communications (20.03.2024)
Published in Nature communications (20.03.2024)
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Journal Article
Standardized GMP-compliant scalable production of human pancreas organoids
Dossena, Marta, Piras, Roberta, Cherubini, Alessandro, Barilani, Mario, Dugnani, Erica, Salanitro, Francesca, Moreth, Till, Pampaloni, Francesco, Piemonti, Lorenzo, Lazzari, Lorenza
Published in Stem cell research & therapy (04.03.2020)
Published in Stem cell research & therapy (04.03.2020)
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Journal Article
circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment
Piras, Roberta, Ko, Emily Y., Barrett, Connor, De Simone, Marco, Lin, Xianzhi, Broz, Marina T., Tessaro, Fernando H. G., Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Goodridge, Helen S., Di Vizio, Dolores, Batish, Mona, Lawrenson, Kate, Chen, Y. Grace, Chan, Keith Syson, Guarnerio, Jlenia
Published in Nature communications (25.11.2022)
Published in Nature communications (25.11.2022)
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Journal Article
1432 Cancer-associated fibroblasts metabolic targeting overcomes T-cell exclusion and chemoresistance
Broz, Marina, Ko, Emily, Ishaya, Kristin, Xiao, Jinfen, DeSimone, Marco, Xen Ping Hoi, Piras, Roberta, Gala, Basia, Fernando HG Tessaro, Orsulic, Sandra, Balzer, Bonnie, Chan, Keith Syson, Guarnerio, Jlenia
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Survival as a clinical outcome and its spiritual significance in a cohort of patients with advanced central pelvic neoplastic disease undergoing total pelvic evisceration: a poorly debated issue
Macciò, Antonio, Sanna, Elisabetta, Piras, Roberta, Lavra, Fabrizio, Vallerino, Valerio, Maricosu, Giovanni, Giglio, Emanuela, Mura, Antonio, Tidore, Marcello, Madeddu, Clelia
Published in Frontiers in medicine (09.06.2023)
Published in Frontiers in medicine (09.06.2023)
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Journal Article
Age‐related changes in the energy of human mesenchymal stem cells
Barilani, Mario, Lovejoy, Christopher, Piras, Roberta, Abramov, Andrey Y., Lazzari, Lorenza, Angelova, Plamena R.
Published in Journal of cellular physiology (01.03.2022)
Published in Journal of cellular physiology (01.03.2022)
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Journal Article
422 DEVELOPMENT OF PATIENT-DERIVED PANCREAS-ON-A-CHIP TO STUDY EXOCRINE AND ENDOCRINE FUNCTIONS SIMULTANEOUSLY
MUN, KYU SHIK, Kim, Hoyeol, Yi, Sujung, Piras, Roberta, Appakalai, Balamurugan N., Pandol, Stephen J., Naren, Anjaparavanda P.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
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Journal Article
Central metabolism of functionally heterogeneous mesenchymal stromal cells
Barilani, Mario, Palorini, Roberta, Votta, Giuseppina, Piras, Roberta, Buono, Giuseppe, Grassi, Michela, Bollati, Valentina, Chiaradonna, Ferdinando, Lazzari, Lorenza
Published in Scientific reports (28.10.2019)
Published in Scientific reports (28.10.2019)
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Journal Article
Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity
Tessaro, Fernando H.G., Ko, Emily Y., De Simone, Marco, Piras, Roberta, Broz, Marina T., Goodridge, Helen S., Balzer, Bonnie, Shiao, Stephen L., Guarnerio, Jlenia
Published in Cell reports (Cambridge) (21.06.2022)
Published in Cell reports (Cambridge) (21.06.2022)
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Journal Article
Abstract 1255: Glucose dependent CD73+ CAFs enforce a tumor metabolic barrier that promotes T cell exclusion
Broz, Marina, Ko, Emily, Xiao, Jinfen, DeSimone, Marco, Piras, Roberta, Ishaya, Kristin, Hoi, Xen Ping, Guarnerio, Jlenia
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation
Naitza, Silvia, Porcu, Eleonora, Steri, Maristella, Taub, Dennis D, Mulas, Antonella, Xiao, Xiang, Strait, James, Dei, Mariano, Lai, Sandra, Busonero, Fabio, Maschio, Andrea, Usala, Gianluca, Zoledziewska, Magdalena, Sidore, Carlo, Zara, Ilenia, Pitzalis, Maristella, Loi, Alessia, Virdis, Francesca, Piras, Roberta, Deidda, Francesca, Whalen, Michael B, Crisponi, Laura, Concas, Antonio, Podda, Carlo, Uzzau, Sergio, Scheet, Paul, Longo, Dan L, Lakatta, Edward, Abecasis, Gonçalo R, Cao, Antonio, Schlessinger, David, Uda, Manuela, Sanna, Serena, Cucca, Francesco
Published in PLoS genetics (01.01.2012)
Published in PLoS genetics (01.01.2012)
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X-Linked Hypohidrotic Ectodermal Dysplasia: New Features and a Novel EDA Gene Mutation
Savasta, Salvatore, Carlone, Giorgia, Castagnoli, Riccardo, Chiappe, Francesca, Bassanese, Francesco, Piras, Roberta, Salpietro, Vincenzo, Brazzelli, Valeria, Verrotti, Alberto, Marseglia, Gian L
Published in Cytogenetic and genome research (01.10.2017)
Published in Cytogenetic and genome research (01.10.2017)
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Preventing antiblastic drug-related cardiomyopathy: old and new therapeutic strategies
Cadeddu, Christian, Mercurio, Valentina, Spallarossa, Paolo, Nodari, Savina, Triggiani, Marco, Monte, Ines, Piras, Roberta, Madonna, Rosalinda, Pagliaro, Pasquale, Tocchetti, Carlo G, Mercuro, Giuseppe
Published in Journal of cardiovascular medicine (Hagerstown, Md.) (01.05.2016)
Published in Journal of cardiovascular medicine (Hagerstown, Md.) (01.05.2016)
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Journal Article
Partial duplication of the PARK2 gene in a child with developmental delay and her normal mother: A second report
Mariani, Milena, Crosti, Francesca, Redaelli, Serena, Fossati, Chiara, Piras, Roberta, Biondi, Andrea, Dalprà, Leda, Selicorni, Angelo
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01.07.2013)
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01.07.2013)
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Journal Article
Partial duplication of the PARK 2 gene in a child with developmental delay and her normal mother: A second report
Mariani, Milena, Crosti, Francesca, Redaelli, Serena, Fossati, Chiara, Piras, Roberta, Biondi, Andrea, Dalprà, Leda, Selicorni, Angelo
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01.07.2013)
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01.07.2013)
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Journal Article
Expanding the Mutational Spectrum of CRLF1 in Crisponi/CISS1 Syndrome
Piras, Roberta, Chiappe, Francesca, Torraca, Ilaria La, Buers, Insa, Usala, Gianluca, Angius, Andrea, Akin, Mustafa Ali, Basel-Vanagaite, Lina, Benedicenti, Francesco, Chiodin, Elisabetta, El Assy, Osama, Feingold-Zadok, Michal, Guibert, Javier, Kamien, Benjamin, Kasapkara, Çiğdem Seher, Kılıç, Esra, Boduroğlu, Koray, Kurtoglu, Selim, Manzur, Adnan Y, Onal, Eray Esra, Paderi, Enrica, Roche, Carmen Herrero, Tümer, Leyla, Unal, Sezin, Utine, Gülen Eda, Zanda, Giovanni, Zankl, Andreas, Zampino, Giuseppe, Crisponi, Giangiorgio, Crisponi, Laura, Rutsch, Frank
Published in Human mutation (01.04.2014)
Published in Human mutation (01.04.2014)
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