Comparative transcriptomic analysis of articular cartilage of post-traumatic osteoarthritis models
Gilbert, Sophie J, Soul, Jamie, Hao, Yao, Lin, Hua, Piróg, Katarzyna A, Coxhead, Jonathan, Patel, Krutik, Barter, Matt J, Young, David A, Blain, Emma J
Published in Disease models & mechanisms (01.10.2024)
Published in Disease models & mechanisms (01.10.2024)
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Journal Article
XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease
Piróg, Katarzyna A, Dennis, Ella P, Hartley, Claire L, Jackson, Robert M, Soul, Jamie, Schwartz, Jean-Marc, Bateman, John F, Boot-Handford, Raymond P, Briggs, Michael D
Published in PLoS genetics (01.07.2019)
Published in PLoS genetics (01.07.2019)
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Journal Article
microRNA-seq of cartilage reveals an overabundance of miR-140-3p which contains functional isomiRs
Woods, Steven, Charlton, Sarah, Cheung, Kat, Hao, Yao, Soul, Jamie, Reynard, Louise N, Crowe, Natalie, Swingler, Tracey E, Skelton, Andrew J, Piróg, Katarzyna A, Miles, Colin G, Tsompani, Dimitra, Jackson, Robert M, Dalmay, Tamas, Clark, Ian M, Barter, Matt J, Young, David A
Published in RNA (Cambridge) (01.11.2020)
Published in RNA (Cambridge) (01.11.2020)
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Journal Article
Increased hippocampal excitability in miR-324-null mice
Hayman, Dan J., Modebadze, Tamara, Charlton, Sarah, Cheung, Kat, Soul, Jamie, Lin, Hua, Hao, Yao, Miles, Colin G., Tsompani, Dimitra, Jackson, Robert M., Briggs, Michael D., Piróg, Katarzyna A., Clark, Ian M., Barter, Matt J., Clowry, Gavin J., LeBeau, Fiona E. N., Young, David A.
Published in Scientific reports (17.05.2021)
Published in Scientific reports (17.05.2021)
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Journal Article
CRELD2 Is a Novel LRP1 Chaperone That Regulates Noncanonical WNT Signaling in Skeletal Development
Dennis, Ella P, Edwards, Sarah M, Jackson, Robert M, Hartley, Claire L, Tsompani, Dimitra, Capulli, Mattia, Teti, Anna, Boot‐Handford, Raymond P, Young, David A, Piróg, Katarzyna A, Briggs, Michael D
Published in Journal of bone and mineral research (01.08.2020)
Published in Journal of bone and mineral research (01.08.2020)
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Journal Article
microRNA-324 mediates bone homeostasis and the regulation of osteoblast and osteoclast differentiation and activity
Hayman, Dan J., Johnson de Sousa Brito, Francesca M., Lin, Hua, Prior, Amanda, Charlesworth, Gemma, Hao, Yao, Pearson, Rachel D., Soul, Jamie, Clark, Ian M., Piróg, Katarzyna A., Barter, Matt J., van't Hof, Rob J., Young, David A.
Published in Bone (New York, N.Y.) (01.01.2025)
Published in Bone (New York, N.Y.) (01.01.2025)
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Journal Article
Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification
Paganini, Chiara, Monti, Luca, Costantini, Rossella, Besio, Roberta, Lecci, Silvia, Biggiogera, Marco, Tian, Kun, Schwartz, Jean-Marc, Huber, Céline, Cormier-Daire, Valérie, Gibson, Beth G., Pirog, Katarzyna A., Forlino, Antonella, Rossi, Antonio
Published in Matrix biology (01.08.2019)
Published in Matrix biology (01.08.2019)
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Journal Article
Abnormal chondrocyte apoptosis in the cartilage growth plate is influenced by genetic background and deletion of CHOP in a targeted mouse model of pseudoachondroplasia
Piróg, Katarzyna A, Irman, Andreja, Young, Siobhan, Halai, Poonam, Bell, Peter A, Boot-Handford, Raymond P, Briggs, Michael D
Published in PloS one (18.02.2014)
Published in PloS one (18.02.2014)
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Journal Article
A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia
Suleman, Farhana, Gualeni, Benedetta, Gregson, Hannah J., Leighton, Matthew P., Piróg, Katarzyna A., Edwards, Sarah, Holden, Paul, Boot-Handford, Raymond P., Briggs, Michael D.
Published in Human mutation (01.01.2012)
Published in Human mutation (01.01.2012)
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Journal Article
Mild myopathy is associated with COMP but not MATN3 mutations in mouse models of genetic skeletal diseases
Piróg, Katarzyna A, Katakura, Yoshihisa, Mironov, Aleksandr, Briggs, Michael D
Published in PloS one (27.11.2013)
Published in PloS one (27.11.2013)
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Journal Article
A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia
Piróg, Katarzyna A., Jaka, Oihane, Katakura, Yoshihisa, Meadows, Roger S., Kadler, Karl E., Boot-Handford, Raymond P., Briggs, Michael D.
Published in Human molecular genetics (01.01.2010)
Published in Human molecular genetics (01.01.2010)
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Journal Article
Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a Matn3 V194D mutation
Bell, Peter A., Piróg, Katarzyna A., Fresquet, Maryline, Thornton, David J., Boot-Handford, Raymond P., Briggs, Michael D.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2012)
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Journal Article
New therapeutic targets in rare genetic skeletal diseases
Briggs, Michael D, Bell, Peter A, Wright, Michael J, Pirog, Katarzyna A
Published in Expert opinion on orphan drugs (03.10.2015)
Published in Expert opinion on orphan drugs (03.10.2015)
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Journal Article
Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP
Piróg-Garcia, Katarzyna A., Meadows, Roger S., Knowles, Lynette, Heinegård, Dick, Thornton, David J., Kadler, Karl E., Boot-Handford, Raymond P., Briggs, Michael D.
Published in Human molecular genetics (01.09.2007)
Published in Human molecular genetics (01.09.2007)
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Journal Article
The utility of mouse models to provide information regarding the pathomolecular mechanisms in human genetic skeletal diseases: The emerging role of endoplasmic reticulum stress (Review)
BRIGGS, MICHAEL D, BELL, PETER A, PIROG, KATARZYNA A
Published in International journal of molecular medicine (01.06.2015)
Published in International journal of molecular medicine (01.06.2015)
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