Myosin Isoform-Dependent Effect of Omecamtiv Mecarbil on the Regulation of Force Generation in Human Cardiac Muscle
Scellini, Beatrice, Piroddi, Nicoletta, Dente, Marica, Pioner, J Manuel, Ferrantini, Cecilia, Poggesi, Corrado, Tesi, Chiara
Published in International journal of molecular sciences (10.09.2024)
Published in International journal of molecular sciences (10.09.2024)
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Journal Article
Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human-induced pluripotent stem cells
Pioner, J Manuel, Guan, Xuan, Klaiman, Jordan M, Racca, Alice W, Pabon, Lil, Muskheli, Veronica, Macadangdang, Jesse, Ferrantini, Cecilia, Hoopmann, Michael R, Moritz, Robert L, Kim, Deok-Ho, Tesi, Chiara, Poggesi, Corrado, Murry, Charles E, Childers, Martin K, Mack, David L, Regnier, Michael
Published in Cardiovascular research (01.02.2020)
Published in Cardiovascular research (01.02.2020)
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Journal Article
Contractile properties of developing human fetal cardiac muscle
Racca, Alice W., Klaiman, Jordan M., Pioner, J. Manuel, Cheng, Yuanhua, Beck, Anita E., Moussavi‐Harami, Farid, Bamshad, Michael J., Regnier, Michael
Published in The Journal of physiology (15.01.2016)
Published in The Journal of physiology (15.01.2016)
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Journal Article
Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues
Bremner, Samantha B, Mandrycky, Christian J, Leonard, Andrea, Padgett, Ruby M, Levinson, Alan R, Rehn, Ethan S, Pioner, J Manuel, Sniadecki, Nathan J, Mack, David L
Published in Journal of tissue engineering (2022)
Published in Journal of tissue engineering (2022)
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Journal Article
Mavacamten depresses human atrial contractility in the same EC50% range as human ventricle
Ferrantini, Cecilia, Scellini, Beatrice, Vitale, Giulia, Pioner, J. Manuel, Querceto, Silvia, Coppini, Raffaele, Piroddi, Nicoletta, Poggesi, Corrado, Tesi, Chiara
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient-induced stem cell-derived cardiomyocyte model of hypertrophic cardiomyopathy
Steczina, Sonette, Mohran, Saffie, Bailey, Logan, McMillen, Tim, Kooiker, Kristina B., Wood, Neil B., Davis, Jennifer M., Previs, Michael J., Olivotto, Iacopo, Pioner, J. Manuel, Geeves, Michael A., Poggesi, Corrado, Regnier, Michael
Published in Biophysical journal (08.02.2024)
Published in Biophysical journal (08.02.2024)
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Journal Article
Full-length dystrophin deficiency leads to contractile and calcium transient defects in human engineered heart tissues
Bremner, Samantha B., Mandrycky, Christian J., Leonard, Andrea, Levinson, Alan R., Rehn, Ethan S., Pioner, J. Manuel, Sniadecki, Nathan J., Mack, David L.
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Contraction and electrophysiological abnormalities in myofilament mutation-positive and mutation-negative human HCM myocardium
Pioner, J. Manuel, Vitale, Giulia, Santini, Lorenzo, Palandri, Chiara, Bueno-Orovio, Alfonso, Margara, Francesca, Piroddi, Nicoletta, Scellini, Beatrice, Tesi, Chiara, Coppini, Raffaele, Ferrantini, Cecilia, Poggesi, Corrado
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Mechanisms of dysfunction in patient-derived cardiomyocytes with the hypertrophic cardiomyopathy-myosin binding protein-C e258K mutation
Steczina, Sonette, Pioner, J. Manuel, Langione, Marianna, Wood, Neil, Vitale, Giulia, Tesi, Chiara, Coppini, Raffaele, Ferrantini, Cecilia, Previs, Michael J., Poggesi, Corrado, Regnier, Michael
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Engineered heart tissues for studying twitch tension and inotropic pharmacological interventions
Langione, Marianna, Pioner, J. Manuel, Steczina, Sonette, Vitale, Giulia, Cerbai, Elisabetta, Tesi, Chiara, Coppini, Raffaele, Regnier, Michael, Poggesi, Corrado, Ferrantini, Cecilia
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Structure-Function Investigation of the E258K-Mybpc3 Mutation in HCM Patient-Derived Cardiomyocytes
Steczina, Sonette, Pioner, J. Manuel, Mohran, Saffie, Langione, Marianna, Vitale, Giulia, Scellini, Beatrice, Piroddi, Nicoletta, Ferrantini, Cecilia, Tesi, Chiara, Geeves, Michael A., Poggesi, Corrado, Regnier, Michael
Published in Biophysical journal (12.02.2021)
Published in Biophysical journal (12.02.2021)
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Journal Article
Advanced Morpho-Functional Analysis on Ventricular and Atrial Tissue Reveals Cross-Bridge Kinetics Alterations and Sarcomere Energetic Impairment in Hcm Patients
Vitale, Giulia, Lazzeri, Erica, Costantini, Irene, Giardini, Francesco, Mazzamuto, Giacomo, Crocini, Claudia, Piroddi, Nicoletta, Scellini, Beatrice, Pioner, Manuel J., Ferrantini, Cecilia, Tesi, Chiara, Pavone, Francesco S., Sacconi, Leonardo, Poggesi, Corrado
Published in Biophysical journal (15.02.2019)
Published in Biophysical journal (15.02.2019)
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Journal Article
Loss of Dystrophin Alters Calcium-Handling Maturation in Response to Microenvironment in Hipsc-Cardiomyocytes from Duchenne Muscular Dystrophy Patients
Pioner, J. Manuel, Coppini, Raffaele, Santini, Lorenzo, Palandri, Chiara, Lupi, Flavia, Langione, Marianna, Benzoni, Patrizia, Landi, Sara, Barbuti, Andrea, Tesi, Chiara, Mack, David L., Regnier, Michael, Parmeggiani, Camilla, Poggesi, Corrado, Ferrantini, Cecilia
Published in Biophysical journal (01.02.2019)
Published in Biophysical journal (01.02.2019)
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Journal Article
Myocardial Dysfunction in Hypertrophic Cardiomyopathy: Primary Effects of Sarcomeric Mutations Versus Secondary EC-Coupling Remodelling
Coppini, Raffaele, Ferrantini, Cecilia, Gentile, Francesca, Mazzoni, Luca, Tosi, Benedetta, Pioner, Manuel J., Scellini, Beatrice, Piroddi, Nicoletta, Tardiff, Jil C., Tesi, Chiara, Cerbai, Elisabetta, Poggesi, Corrado
Published in Biophysical journal (27.01.2015)
Published in Biophysical journal (27.01.2015)
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Journal Article
Life-Long Treatment with Late Sodium Current Blocker Reduces Myocardial Dysfunction and Remodeling in a Mouse Model of Hypertrophic Cardiomyopathy
Gentile, Francesca, Coppini, Raffaele, Ferrantini, Cecilia, Mazzoni, luca, Pioner, Manuel J, Tosi, Benedetta, Scellini, Beatrice, Mugelli, Alessandro, Cerbai, Elisabetta, Tardif, Jill, Tesi, Chiara, Poggesi, Corrado
Published in Biophysical journal (27.01.2015)
Published in Biophysical journal (27.01.2015)
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Journal Article
Mechanical Effects of Late Na-Current Blockers in Human Hypertrophic Cardiomyopathy Myocardium
Ferrantini, Cecilia, Coppini, Raffaele, Pioner, Manuel J., Francesca, Gentile, Benedetta, Tosi, Mazzoni, Luca, Belardinelli, Luiz, Tesi, Chiara, Cerbai, Elisabetta, Mugelli, Alessandro, Poggesi, Corrado
Published in Biophysical journal (27.01.2015)
Published in Biophysical journal (27.01.2015)
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Journal Article
Increased CAMKII Activity Impairs Contractile Function in Human HCM Myocardium
Coppini, Raffaele, Ferrantini, Cecilia, Pioner, Manuel J., Yao, Lina, Fan, Peidong, Tosi, Benedetta, Cerbai, Elisabetta, Belardinelli, Luiz, Tesi, Chiara, Poggesi, Corrado
Published in Biophysical journal (28.01.2014)
Published in Biophysical journal (28.01.2014)
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