Highly Potent and Selective Nonsteroidal Dual Inhibitors of CYP17/CYP11B2 for the Treatment of Prostate Cancer To Reduce Risks of Cardiovascular Diseases
Pinto-Bazurco Mendieta, Mariano A. E, Hu, Qingzhong, Engel, Matthias, Hartmann, Rolf W
Published in Journal of medicinal chemistry (08.08.2013)
Published in Journal of medicinal chemistry (08.08.2013)
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Journal Article
Synthesis, Biological Evaluation, and Molecular Modeling of Abiraterone Analogues: Novel CYP17 Inhibitors for the Treatment of Prostate Cancer
Pinto-Bazurco Mendieta, Mariano A. E, Negri, Matthias, Jagusch, Carsten, Müller-Vieira, Ursula, Lauterbach, Thomas, Hartmann, Rolf W
Published in Journal of medicinal chemistry (28.08.2008)
Published in Journal of medicinal chemistry (28.08.2008)
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Journal Article
CYP17 Inhibitors. Annulations of Additional Rings in Methylene Imidazole Substituted Biphenyls: Synthesis, Biological Evaluation and Molecular Modelling
Pinto-Bazurco Mendieta, Mariano A. E., Negri, Matthias, Hu, Qingzhong, Hille, Ulrike E., Jagusch, Carsten, Jahn-Hoffmann, Kerstin, Müller-Vieira, Ursula, Schmidt, Dirk, Lauterbach, Thomas, Hartmann, Rolf W.
Published in Archiv der Pharmazie (Weinheim) (01.10.2008)
Published in Archiv der Pharmazie (Weinheim) (01.10.2008)
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Journal Article
Synthesis, biological evaluation and molecular modelling studies of novel ACD- and ABD-ring steroidomimetics as inhibitors of CYP17
Pinto-Bazurco Mendieta, Mariano A.E., Negri, Matthias, Jagusch, Carsten, Hille, Ulrike E., Müller-Vieira, Ursula, Schmidt, Dirk, Hansen, Klaus, Hartmann, Rolf W.
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Journal Article
Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17α-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure
Jagusch, Carsten, Negri, Matthias, Hille, Ulrike E., Hu, Qingzhong, Bartels, Marc, Jahn-Hoffmann, Kerstin, Mendieta, Mariano A.E. Pinto-Bazurco, Rodenwaldt, Barbara, Müller-Vieira, Ursula, Schmidt, Dirk, Lauterbach, Thomas, Recanatini, Maurizio, Cavalli, Andrea, Hartmann, Rolf W.
Published in Bioorganic & medicinal chemistry (15.02.2008)
Published in Bioorganic & medicinal chemistry (15.02.2008)
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Journal Article
Steroidogenic cytochrome P450 (CYP) enzymes as drug targets: Combining substructures of known CYP inhibitors leads to compounds with different inhibitory profile
Hille, Ulrike E., Hu, Qingzhong, Pinto-Bazurco Mendieta, Mariano A.E., Bartels, Marc, Vock, Carsten A., Lauterbach, Thomas, Hartmann, Rolf W.
Published in Comptes rendus. Chimie (01.10.2009)
Published in Comptes rendus. Chimie (01.10.2009)
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Journal Article
ChemInform Abstract: CYP17 Inhibitors. Annulations of Additional Rings in Methylene Imidazole Substituted Biphenyls: Synthesis, Biological Evaluation and Molecular Modelling
Pinto-Bazurco Mendieta, Mariano A. E., Negri, Matthias, Hu, Qingzhong, Hille, Ulrike E., Jagusch, Carsten, Jahn-Hoffmann, Kerstin, Mueller-Vieira, Ursula, Schmidt, Dirk, Lauterbach, Thomas, Hartmann, Rolf W.
Published in ChemInform (10.02.2009)
Published in ChemInform (10.02.2009)
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Journal Article
ChemInform Abstract: Synthesis, Biological Evaluation and Molecular Modelling Studies of Novel ACD- and ABD-Ring Steroidomimetics as Inhibitors of CYP17
Pinto-Bazurco Mendieta, Mariano A. E., Negri, Matthias, Jagusch, Carsten, Hille, Ulrike E., Mueller-Vieira, Ursula, Schmidt, Dirk, Hansen, Klaus, Hartmann, Rolf W.
Published in ChemInform (10.06.2008)
Published in ChemInform (10.06.2008)
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Steroidogenic cytochrome P450 (CYP) enzymes as drug targets: Combining substructures of known CYP inhibitors leads to compounds with different inhibitory profile: Méthodes physiques pour l'étude structurale de nouveaux matériaux
HILLE, Ulrike E, QINGZHONG HU, PINTO-BAZURCO MENDIETA, Mariano A. E, BARTELS, Marc, VOCK, Carsten A, LAUTERBACH, Thomas, HARTMANN, Rolf W
Published in Comptes rendus. Chimie (2009)
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Published in Comptes rendus. Chimie (2009)
Journal Article
Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17a-hydroxylase-17,20-lyase (CYP17). Part I : Heterocyclic modifications of the core structure
JAGUSCH, Carsten, NEGRI, Matthias, LAUTERBACH, Thomas, RECANATINI, Maurizio, CAVALLI, Andrea, HARTMANN, Rolf W, HILLE, Ulrike E, QINGZHONG HU, BARTELS, Marc, JAHN-HOFFMANN, Kerstin, PINTO-BAZURCO MENDIETA, Mariano A. E, RODENWALDT, Barbara, MÜLLER-VIEIRA, Ursula, SCHMIDT, Dirk
Published in Bioorganic & medicinal chemistry (2008)
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Published in Bioorganic & medicinal chemistry (2008)
Journal Article
Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure
Jagusch, Carsten, Negri, Matthias, Hille, Ulrike E, Hu, Qingzhong, Bartels, Marc, Jahn-Hoffmann, Kerstin, Pinto-Bazurco Mendieta, Mariano A E, Rodenwaldt, Barbara, Müller-Vieira, Ursula, Schmidt, Dirk, Lauterbach, Thomas, Recanatini, Maurizio, Cavalli, Andrea, Hartmann, Rolf W
Published in Bioorganic & medicinal chemistry (15.02.2008)
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Published in Bioorganic & medicinal chemistry (15.02.2008)
Journal Article