The effects on Trypanosoma cruzi of novel synthetic naphthoquinones are mediated by mitochondrial dysfunction
Menna-Barreto, Rubem F.S., Goncalves, Renata L.S., Costa, Elaine M., Silva, Raphael S.F., Pinto, Antonio V., Oliveira, Marcus F., de Castro, Solange L.
Published in Free radical biology & medicine (01.09.2009)
Published in Free radical biology & medicine (01.09.2009)
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Cytotoxicity of lapachol, beta-lapachone and related synthetic 1,4-naphthoquinones against oesophageal cancer cells
Sunassee, Suthananda N., Veale, Clinton G. L., Shunmoogam-Gounden, Nelusha, Osoniyi, Omalaja, Hendricks, Denver T., Caira, Mino R., de la Mare, Jo-Anne, Edkins, Adrienne L., Pinto, Antonio V., da Silva Junior, Eufranio N., Davies-Coleman, Michael T.
Published in European journal of medicinal chemistry (01.04.2013)
Published in European journal of medicinal chemistry (01.04.2013)
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Journal Article
Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi
da Silva, Eufrânio N., Menna-Barreto, Rubem F.S., Pinto, Maria do Carmo F.R., Silva, Raphael S.F., Teixeira, Daniel V., de Souza, Maria Cecília B.V., De Simone, Carlos Alberto, De Castro, Solange L., Ferreira, Vitor F., Pinto, Antônio V.
Published in European journal of medicinal chemistry (01.08.2008)
Published in European journal of medicinal chemistry (01.08.2008)
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Journal Article
3-Arylamino and 3-Alkoxy-nor-β-lapachone Derivatives: Synthesis and Cytotoxicity against Cancer Cell Lines
da Silva Júnior, Eufrânio N, de Deus, Clara F, Cavalcanti, Bruno C, Pessoa, Cláudia, Costa-Lotufo, Letícia V, Montenegro, Raquel C, de Moraes, Manoel O, Pinto, Maria do Carmo F. R, de Simone, Carlos A, Ferreira, Vitor F, Goulart, Marilia O. F, Andrade, Carlos Kleber Z, Pinto, Antônio V
Published in Journal of medicinal chemistry (14.01.2010)
Published in Journal of medicinal chemistry (14.01.2010)
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Journal Article
2-(4-Methyl-phen-yl)-1H-anthraceno[1,2-d]imidazole-6,11-dione: a fluorescent chemosensor
Guimarães, Tiago T, Da Silva Júnior, Eufrânio N, Carvalho, Carlos Eduardo M, De Simone, Carlos A, Pinto, Antonio V
Published in Acta crystallographica. Section E, Structure reports online (18.04.2009)
Published in Acta crystallographica. Section E, Structure reports online (18.04.2009)
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Journal Article
Synthesis and evaluation of quinonoid compounds against tumor cell lines
da Silva, Eufrânio N., Cavalcanti, Bruno C., Guimarães, Tiago T., Pinto, Maria do Carmo F.R., Cabral, Igor O., Pessoa, Cláudia, Costa-Lotufo, Letícia V., de Moraes, Manoel O., de Andrade, Carlos K.Z., dos Santos, Marcelo R., de Simone, Carlos A., Goulart, Marilia O.F., Pinto, Antonio V.
Published in European journal of medicinal chemistry (01.01.2011)
Published in European journal of medicinal chemistry (01.01.2011)
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Journal Article
Synthesis and anti- Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones
da Silva Júnior, Eufrânio N., de Souza, Maria Cecília B.V., Fernandes, Michelle C., Menna-Barreto, Rubem F.S., Pinto, Maria do Carmo F.R., de Assis Lopes, Francisco, de Simone, Carlos Alberto, Andrade, Carlos Kleber Z., Pinto, Antônio V., Ferreira, Vitor F., de Castro, Solange L.
Published in Bioorganic & medicinal chemistry (01.05.2008)
Published in Bioorganic & medicinal chemistry (01.05.2008)
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Journal Article
Antimalarial activity of phenazines from lapachol, β-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo
DE ANDRADE-NETO, Valter F, GOULART, Marilia O. F, DA SILVA, Jorge F, DA SILVA, Matuzalém J, PINTO, Maria Do Carmo F. R, PINTO, Antonio V, ZALIS, Mariano G, CARVALHO, Luzia H, KRETTLI, Antoniana U
Published in Bioorganic & medicinal chemistry letters (08.03.2004)
Published in Bioorganic & medicinal chemistry letters (08.03.2004)
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Journal Article
Synthesis and potent antitumor activity of new arylamino derivatives of nor-β-lapachone and nor-α-lapachone
da Silva Júnior, Eufrânio N., de Souza, Maria Cecília B.V., Pinto, Antônio V., Pinto, Maria do Carmo F.R., Goulart, Marilia O.F., Barros, Francisco W.A., Pessoa, Claudia, Costa-Lotufo, Letícia V., Montenegro, Raquel C., de Moraes, Manoel O., Ferreira, Vitor F.
Published in Bioorganic & medicinal chemistry (15.11.2007)
Published in Bioorganic & medicinal chemistry (15.11.2007)
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Journal Article
1,4- Addition of diazomethane to a heterodiene: a direct preparation of the oxazolic ring
Emery, Flávio da S, Silva, Raphael S F, de Moura, Kelly C G, Pinto, Maria C F R, Amorim, Mauro B, Malta, Valéria R S, Santos, Regina H A, Honório, Kátia M, da Silva, Albérico B F, Pinto, Antonio V
Published in Anais da Academia Brasileira de Ciências (01.03.2007)
Published in Anais da Academia Brasileira de Ciências (01.03.2007)
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The evaluation of quinonoid compounds against Trypanosoma cruzi: Synthesis of imidazolic anthraquinones, nor-β-lapachone derivatives and β-lapachone-based 1,2,3-triazoles
da Silva Júnior, Eufrânio N., Guimarães, Tiago T., Menna-Barreto, Rubem F.S., Pinto, Maria do Carmo F.R., de Simone, Carlos A., Pessoa, Claudia, Cavalcanti, Bruno C., Sabino, José R., Andrade, Carlos Kleber Z., Goulart, Marilia O.F., de Castro, Solange L., Pinto, Antônio V.
Published in Bioorganic & medicinal chemistry (01.05.2010)
Published in Bioorganic & medicinal chemistry (01.05.2010)
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Journal Article
New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms
Carneiro, Paula F., do Nascimento, Samara B., Pinto, Antonio V., Pinto, Maria do Carmo F.R., Lechuga, Guilherme C., Santos, Dilvani O., dos Santos Júnior, Helvécio M., Resende, Jackson A.L.C., Bourguignon, Saulo C., Ferreira, Vitor F.
Published in Bioorganic & medicinal chemistry (15.08.2012)
Published in Bioorganic & medicinal chemistry (15.08.2012)
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Journal Article
Effect of a β-lapachone-derived naphthoimidazole on Trypanosoma cruzi: identification of target organelles
Menna-Barreto, Rubem F. S., Henriques-Pons, Andrea, Pinto, Antônio V., Morgado-Diaz, José A., Soares, Maurilio J., De Castro, Solange L.
Published in Journal of antimicrobial chemotherapy (01.12.2005)
Published in Journal of antimicrobial chemotherapy (01.12.2005)
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Quinonoid and phenazine compounds: Synthesis and evaluation against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosis
Carneiro, Paula F., Pinto, Maria do Carmo F. R., Coelho, Tatiane S., Cavalcanti, Bruno C., Pessoa, Claudia, de Simone, Carlos A., Nunes, Isabelle K. C., de Oliveira, Nathalia M., de Almeida, Renata G., Pinto, Antonio V., de Moura, Kelly C. G., da Silva, Pedro A., da Silva Junior, Eufranio N.
Published in European journal of medicinal chemistry (01.09.2011)
Published in European journal of medicinal chemistry (01.09.2011)
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Journal Article
Trypanocidal agents with low cytotoxicity to mammalian cell line: A comparison of the theoretical and biological features of lapachone derivatives
Ferreira, Vitor F., Jorqueira, Alessandra, Souza, Alessandra M.T., da Silva, Milton N., de Souza, Maria C.B.V., Gouvêa, Robson M., Rodrigues, Carlos R., Pinto, Antonio V., Castro, Helena C., Santos, Dilvani O., Araújo, Humberto P., Bourguignon, Saulo C.
Published in Bioorganic & medicinal chemistry (15.08.2006)
Published in Bioorganic & medicinal chemistry (15.08.2006)
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A proteomic analysis of the mechanism of action of naphthoimidazoles in Trypanosoma cruzi epimastigotes in vitro
Menna-Barreto, Rubem F.S., Beghini, Daniela G., Ferreira, André T.S., Pinto, Antônio V., De Castro, Solange L., Perales, Jonas
Published in Journal of proteomics (10.11.2010)
Published in Journal of proteomics (10.11.2010)
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Journal Article
Activity of β-lapachone derivatives against rifampicin-susceptible and -resistant strains of Mycobacterium tuberculosis
Coelho, Tatiane S, Silva, Raphael S.F, Pinto, Antonio V, Pinto, Maria C.F.R, Scaini, Carlos J, Moura, Kelly C.G, Almeida da Silva, Pedro
Published in Tuberculosis (Edinburgh, Scotland) (01.09.2010)
Published in Tuberculosis (Edinburgh, Scotland) (01.09.2010)
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Journal Article
Identification of Nor-β-Lapachone Derivatives as Potential Antibacterial Compounds against Enterococcus faecalis Clinical Strain
Lourenço, André L, Abreu, Paula A, Leal, Bruno, da Silva Júnior, Eufrânio N, Pinto, Antonio V, Pinto, Maria do Carmo F. R, Souza, Alessandra M. T, Novais, Juliana S, Paiva, Marcela B, Cabral, Lucio M, Rodrigues, Carlos R, Ferreira, Vitor F, Castro, Helena C
Published in Current microbiology (01.02.2011)
Published in Current microbiology (01.02.2011)
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Journal Article
A macrolactone from benzo[ a]phenazine with potent activity against Mycobacterium tuberculosis
Silva, Raphael S.F., Pinto, Maria do Carmo F.R., Goulart, Marília O.F., de Souza Filho, José D., Neves, Ivan, Lourenço, Maria Cristina S., Pinto, Antonio V.
Published in European journal of medicinal chemistry (01.05.2009)
Published in European journal of medicinal chemistry (01.05.2009)
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