Applications of organocatalysed visible-light photoredox reactions for medicinal chemistry
Bogdos, Michael K, Pinard, Emmanuel, Murphy, John A
Published in Beilstein journal of organic chemistry (03.08.2018)
Published in Beilstein journal of organic chemistry (03.08.2018)
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Journal Article
Discovery of Risdiplam, a Selective Survival of Motor Neuron‑2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)
Ratni, Hasane, Ebeling, Martin, Baird, John, Bendels, Stefanie, Bylund, Johan, Chen, Karen S, Denk, Nora, Feng, Zhihua, Green, Luke, Guerard, Melanie, Jablonski, Philippe, Jacobsen, Bjoern, Khwaja, Omar, Kletzl, Heidemarie, Ko, Chien-Ping, Kustermann, Stefan, Marquet, Anne, Metzger, Friedrich, Mueller, Barbara, Naryshkin, Nikolai A, Paushkin, Sergey V, Pinard, Emmanuel, Poirier, Agnès, Reutlinger, Michael, Weetall, Marla, Zeller, Andreas, Zhao, Xin, Mueller, Lutz
Published in Journal of medicinal chemistry (09.08.2018)
Published in Journal of medicinal chemistry (09.08.2018)
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Journal Article
Glycine Transporter Type I (GlyT1) Inhibitor, Bitopertin: A Journey from Lab to Patient
Pinard, Emmanuel, Borroni, Edilio, Koerner, Annette, Umbricht, Daniel, Alberati, Daniela
Published in Chimia (22.08.2018)
Published in Chimia (22.08.2018)
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Journal Article
Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophrenia
Alberati, Daniela, Moreau, Jean-Luc, Lengyel, Judith, Hauser, Nicole, Mory, Roland, Borroni, Edilio, Pinard, Emmanuel, Knoflach, Frederic, Schlotterbeck, Götz, Hainzl, Dominik, Wettstein, Joseph G.
Published in Neuropharmacology (01.02.2012)
Published in Neuropharmacology (01.02.2012)
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Journal Article
Biochemical and Electrophysiological Characterization of Almorexant, a Dual Orexin 1 Receptor (OX1)/Orexin 2 Receptor (OX2) Antagonist: Comparison with Selective OX1 and OX2 Antagonists
Malherbe, Pari, Borroni, Edilio, Pinard, Emmanuel, Wettstein, Joseph G, Knoflach, Frédéric
Published in Molecular pharmacology (01.09.2009)
Published in Molecular pharmacology (01.09.2009)
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Journal Article
Selective GlyT1 Inhibitors: Discovery of [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia
Pinard, Emmanuel, Alanine, Alexander, Alberati, Daniela, Bender, Markus, Borroni, Edilio, Bourdeaux, Patrick, Brom, Virginie, Burner, Serge, Fischer, Holger, Hainzl, Dominik, Halm, Remy, Hauser, Nicole, Jolidon, Synese, Lengyel, Judith, Marty, Hans-Peter, Meyer, Thierry, Moreau, Jean-Luc, Mory, Roland, Narquizian, Robert, Nettekoven, Mathias, Norcross, Roger D, Puellmann, Bernd, Schmid, Philipp, Schmitt, Sebastien, Stalder, Henri, Wermuth, Roger, Wettstein, Joseph G, Zimmerli, Daniel
Published in Journal of medicinal chemistry (24.06.2010)
Published in Journal of medicinal chemistry (24.06.2010)
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Journal Article
BACE1 inhibitors: A head group scan on a series of amides
Woltering, Thomas J., Wostl, Wolfgang, Hilpert, Hans, Rogers-Evans, Mark, Pinard, Emmanuel, Mayweg, Alexander, Göbel, Martin, Banner, David W., Benz, Jörg, Travagli, Massimiliano, Pollastrini, Martina, Marconi, Guido, Gabellieri, Emanuele, Guba, Wolfgang, Mauser, Harald, Andreini, Matteo, Jacobsen, Helmut, Power, Eoin, Narquizian, Robert
Published in Bioorganic & medicinal chemistry letters (15.07.2013)
Published in Bioorganic & medicinal chemistry letters (15.07.2013)
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Journal Article
The Voltage-dependent Anion Channel Is the Target for a New Class of Inhibitors of the Mitochondrial Permeability Transition Pore
Cesura, Andrea M., Pinard, Emmanuel, Schubenel, Robert, Goetschy, Valerie, Friedlein, Arno, Langen, Hanno, Polcic, Peter, Forte, Michael A., Bernardi, Paolo, Kemp, John A.
Published in The Journal of biological chemistry (12.12.2003)
Published in The Journal of biological chemistry (12.12.2003)
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Journal Article
Structural insights into the inhibition of glycine reuptake
Shahsavar, Azadeh, Stohler, Peter, Bourenkov, Gleb, Zimmermann, Iwan, Siegrist, Martin, Guba, Wolfgang, Pinard, Emmanuel, Sinning, Steffen, Seeger, Markus A., Schneider, Thomas R., Dawson, Roger J. P., Nissen, Poul
Published in Nature (London) (25.03.2021)
Published in Nature (London) (25.03.2021)
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Journal Article
The Mitochondrial Effects of Small Organic Ligands of BCL-2
Milanesi, Eva, Costantini, Paola, Gambalunga, Alberto, Colonna, Raffaele, Petronilli, Valeria, Cabrelle, Anna, Semenzato, Gianpietro, Cesura, Andrea M., Pinard, Emmanuel, Bernardi, Paolo
Published in The Journal of biological chemistry (14.04.2006)
Published in The Journal of biological chemistry (14.04.2006)
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Journal Article
Discovery of Balovaptan, a Vasopressin la Receptor Antagonist for the Treatment of Autism Spectrum Disorder
Schnider, Patrick, Bissantz, Caterina, Bruns, Andreas, Dolente, Cosimo, Goetschi, Erwin, Jakob-Roetne, Roland, Kuennecke, Basil, Mueggler, Thomas, Muster, Wolfgang, Parrott, Neil, Pinard, Emmanuel, Ratni, Hasane, Risterucci, Celine, Rogers-Evans, Mark, von Kienlin, Markus, Grundschober, Christophe
Published in Journal of medicinal chemistry (27.02.2020)
Published in Journal of medicinal chemistry (27.02.2020)
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Journal Article
A Real-World Perspective on Molecular Design
Kuhn, Bernd, Guba, Wolfgang, Hert, Jérôme, Banner, David, Bissantz, Caterina, Ceccarelli, Simona, Haap, Wolfgang, Körner, Matthias, Kuglstatter, Andreas, Lerner, Christian, Mattei, Patrizio, Neidhart, Werner, Pinard, Emmanuel, Rudolph, Markus G, Schulz-Gasch, Tanja, Woltering, Thomas, Stahl, Martin
Published in Journal of medicinal chemistry (12.05.2016)
Published in Journal of medicinal chemistry (12.05.2016)
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Journal Article
Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy
Ratni, Hasane, Karp, Gary M, Weetall, Marla, Naryshkin, Nikolai A, Paushkin, Sergey V, Chen, Karen S, McCarthy, Kathleen D, Qi, Hongyan, Turpoff, Anthony, Woll, Matthew G, Zhang, Xiaoyan, Zhang, Nanjing, Yang, Tianle, Dakka, Amal, Vazirani, Priya, Zhao, Xin, Pinard, Emmanuel, Green, Luke, David-Pierson, Pascale, Tuerck, Dietrich, Poirier, Agnes, Muster, Wolfgang, Kirchner, Stephan, Mueller, Lutz, Gerlach, Irene, Metzger, Friedrich
Published in Journal of medicinal chemistry (14.07.2016)
Published in Journal of medicinal chemistry (14.07.2016)
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Journal Article
β‑Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease
Hilpert, Hans, Guba, Wolfgang, Woltering, Thomas J, Wostl, Wolfgang, Pinard, Emmanuel, Mauser, Harald, Mayweg, Alexander V, Rogers-Evans, Mark, Humm, Roland, Krummenacher, Daniela, Muser, Thorsten, Schnider, Christian, Jacobsen, Helmut, Ozmen, Laurence, Bergadano, Alessandra, Banner, David W, Hochstrasser, Remo, Kuglstatter, Andreas, David-Pierson, Pascale, Fischer, Holger, Polara, Alessandra, Narquizian, Robert
Published in Journal of medicinal chemistry (23.05.2013)
Published in Journal of medicinal chemistry (23.05.2013)
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Journal Article
Total Synthesis of the Lycopodium Alkaloids Magellanine and Magellaninone by Three-fold Annulation of 2-Cyclopentenone
Williams, John P, Friedrich, Dirk, Pinard, Emmanuel, Roden, Brian A, Paquette, Leo A, St. Laurent, D. R
Published in Journal of the American Chemical Society (01.06.1994)
Published in Journal of the American Chemical Society (01.06.1994)
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Journal Article
Discovery of Orally Available and Brain Penetrant AEP Inhibitors
Krummenacher, Daniela, He, Weiping, Kuhn, Bernd, Schnider, Christian, Beurier, Angélica, Brom, Virginie, Sivasothy, Thulase, Marty, Christine, Tosstorff, Andreas, Hewings, David S., Mesch, Stefanie, Pinard, Emmanuel, Brändlin, Mathis, Hochstrasser, Remo, Westwood, Paul, Rothe, Judith, Kronenberger, Alexandra, Morandi, Federica, Gutbier, Simon, Schuler, Angelika, Heer, Dominik, Gloria, Ludivine Esteves, Joedicke, Lisa, Rudolph, Markus G., Müller, Lutz, Grüninger, Fiona, Baumann, Karlheinz, Kaniyappan, Senthilvelrajan, Manevski, Nenad, Bartels, Björn
Published in Journal of medicinal chemistry (28.12.2023)
Published in Journal of medicinal chemistry (28.12.2023)
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Journal Article
Discovery of a Novel Class of Survival Motor Neuron 2 Splicing Modifiers for the Treatment of Spinal Muscular Atrophy
Pinard, Emmanuel, Green, Luke, Reutlinger, Michael, Weetall, Marla, Naryshkin, Nikolai A, Baird, John, Chen, Karen S, Paushkin, Sergey V, Metzger, Friedrich, Ratni, Hasane
Published in Journal of medicinal chemistry (25.05.2017)
Published in Journal of medicinal chemistry (25.05.2017)
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Journal Article
Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum Disorder
Schnider, Patrick, Bissantz, Caterina, Bruns, Andreas, Dolente, Cosimo, Goetschi, Erwin, Jakob-Roetne, Roland, Künnecke, Basil, Mueggler, Thomas, Muster, Wolfgang, Parrott, Neil, Pinard, Emmanuel, Ratni, Hasane, Risterucci, Céline, Rogers-Evans, Mark, von Kienlin, Markus, Grundschober, Christophe
Published in Journal of medicinal chemistry (27.02.2020)
Published in Journal of medicinal chemistry (27.02.2020)
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Journal Article
신규 피리미딘-2-일 설폰아미드 유도체
GALLEY GUIDO, MAZUNIN DMITRY, RICCI ANTONIO, PINARD EMMANUEL, GOBBI LUCA, GUBA WOLFGANG
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
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