A new scaffold-free tumoroid model provides a robust preclinical tool to investigate invasion and drug response in Renal Cell Carcinoma
Séraudie, Irinka, Pillet, Catherine, Cesana, Beatrice, Bazelle, Pauline, Jeanneret, Florian, Evrard, Bertrand, Chalmel, Frédéric, Bouzit, Assilah, Battail, Christophe, Long, Jean-Alexandre, Descotes, Jean Luc, Cochet, Claude, Filhol, Odile
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Published in Cell death & disease (22.09.2023)
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Ex-Vivo Treatment of Tumor Tissue Slices as a Predictive Preclinical Method to Evaluate Targeted Therapies for Patients with Renal Carcinoma
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Published in Cancers (17.01.2020)
Published in Cancers (17.01.2020)
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Combined inhibition of PI3K and Src kinases demonstrates synergistic therapeutic efficacy in clear-cell renal carcinoma
Roelants, Caroline, Giacosa, Sofia, Pillet, Catherine, Bussat, Rémi, Champelovier, Pierre, Bastien, Olivier, Guyon, Laurent, Arnoux, Valentin, Cochet, Claude, Filhol, Odile
Published in Oncotarget (10.07.2018)
Published in Oncotarget (10.07.2018)
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Cooperative Blockade of CK2 and ATM Kinases Drives Apoptosis in VHL-Deficient Renal Carcinoma Cells through ROS Overproduction
Giacosa, Sofia, Pillet, Catherine, Séraudie, Irinka, Guyon, Laurent, Wallez, Yann, Roelants, Caroline, Battail, Christophe, Evrard, Bertrand, Chalmel, Frédéric, Barette, Caroline, Soleilhac, Emmanuelle, Fauvarque, Marie-Odile, Franquet, Quentin, Sarrazin, Clément, Peilleron, Nicolas, Fiard, Gaëlle, Long, Jean-Alexandre, Descotes, Jean-Luc, Cochet, Claude, Filhol, Odile
Published in Cancers (02.02.2021)
Published in Cancers (02.02.2021)
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Pharmacological Inhibition of LIM Kinase Stabilizes Microtubules and Inhibits Neoplastic Growth
PRUDENT, Renaud, VASSAL-STERMANN, Emilie, VALDAMERI, Glaucio, HONORE, Stéphane, ACI-SECHE, Samia, GRIERSON, David, ANTONIPILLAI, Juliana, RONG LI, DI PIETRO, Attilio, DUMONTET, Charles, BRAGUER, Diane, FLORENT, Jean-Claude, NGUYEN, Chi-Hung, KNAPP, Stefan, BERNARD, Ora, LAFANECHERE, Laurence, PILLET, Catherine, MARTINEZ, Anne, PRUNIER, Chloe, BARETTE, Caroline, SOLEILHAC, Emmanuelle, FILHOL, Odile, BEGHIN, Anne
Published in Cancer research (Chicago, Ill.) (01.09.2012)
Published in Cancer research (Chicago, Ill.) (01.09.2012)
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Cancer selective cell death induction by a bivalent CK2 inhibitor targeting the ATP site and the allosteric αD pocket
Bancet, Alexandre, Frem, Rita, Jeanneret, Florian, Mularoni, Angélique, Bazelle, Pauline, Roelants, Caroline, Delcros, Jean-Guy, Guichou, Jean-François, Pillet, Catherine, Coste, Isabelle, Renno, Toufic, Battail, Christophe, Cochet, Claude, Lomberget, Thierry, Filhol, Odile, Krimm, Isabelle
Published in iScience (16.02.2024)
Published in iScience (16.02.2024)
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A Nucleolar Isoform of the Drosophila Ubiquitin Specific Protease dUSP36 Regulates MYC-Dependent Cell Growth
Thevenon, Dominique, Seffouh, Ilham, Pillet, Catherine, Crespo-Yanez, Xenia, Fauvarque, Marie-Odile, Taillebourg, Emmanuel
Published in Frontiers in cell and developmental biology (19.06.2020)
Published in Frontiers in cell and developmental biology (19.06.2020)
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Novel synthetic pharmacophores inducing a stabilization of cellular microtubules
Martinez, Anne, Soleilhac, Emmanuelle, Barette, Caroline, Prudent, Renaud, Gozzi, Gustavo J, Vassal-Stermann, Emilie, Pillet, Catherine, Di Pietro, Attilio, Fauvarque, Marie-Odile, Lafanechere, Laurence
Published in Current cancer drug targets (01.01.2015)
Published in Current cancer drug targets (01.01.2015)
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Correction: Combined inhibition of PI3K and Src kinases demonstrates synergistic therapeutic efficacy in clear-cell renal carcinoma
Caroline, Roelants, Sofia, Giacosa, Catherine, Pillet, Remi, Bussat, Pierre, Champelovier, Olivier, Bastien, Laurent, Guyon, Valentin, Arnoux, Claude, Cochet, Odile, Filhol
Published in Oncotarget (15.03.2019)
Published in Oncotarget (15.03.2019)
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Azaindole derivatives are inhibitors of microtubule dynamics, with anti‐cancer and anti‐angiogenic activities
Prudent, Renaud, Vassal‐Stermann, Émilie, Nguyen, Chi‐Hung, Mollaret, Marjorie, Viallet, Jean, Desroches‐Castan, Agnès, Martinez, Anne, Barette, Caroline, Pillet, Catherine, Valdameri, Glaucio, Soleilhac, Emmanuelle, Di Pietro, Attilio, Feige, Jean‐Jacques, Billaud, Marc, Florent, Jean‐Claude, Lafanechère, Laurence
Published in British journal of pharmacology (01.02.2013)
Published in British journal of pharmacology (01.02.2013)
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Heterocyclic naphthoquinones derivatives for use in the treatment of cancers including Cushing disease
Pillet, Catherine, Soleilhac, Emmanuelle, Vanelle, Patrice, Barette, Caroline, Remusat, Vincent, Mortier, Magda, Aguilar, Carmen, Terme, Thierry, Fauvarque, Marie-Odile
Year of Publication 19.04.2022
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Year of Publication 19.04.2022
Patent
HETEROCYCLIC NAPHTHOQUINONES DERIVATIVES FOR USE IN THE TREATMENT OF CANCERS INCLUDING CUSHING DISEASE
SOLEILHAC, Emmanuelle, TERME, Thierry, VANELLE, Patrice, REMUSAT, Vincent, BARETTE, Caroline, FAUVARQUE, Marie-Odile, AGUILAR, Carmen, MORTIER, Magda, PILLET, Catherine
Year of Publication 19.01.2022
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Year of Publication 19.01.2022
Patent
Microenvironment of metastasis reveals key predictors of PD-1 blockade response in renal cell carcinoma
Jeanneret, Florian, Bazelle, Pauline, Schoch, Sarah, Pillet, Catherine, In Hwa Um, Bouzit, Assilah, Evrard, Bertrand, Seffar, Evan, Chalmel, Frederic, Alfaro, Javier A, Pesquita, Catia, Zanzotto, Fabio Massimo, Stares, Mark, Symeonides, Stefan N, Laird, Alexander, Jean-Alexandre Long, Descotes, Jean Luc, Pflieger, Delphine, Harrison, David J, Filhol, Odile, Axelson, Hakan, Battail, Christophe
Published in bioRxiv (11.01.2024)
Published in bioRxiv (11.01.2024)
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Paper
Synthetic lethal drug combination for treating renal cell carcinoma
Cochet, Claude, Pillet, Catherine, Soleilhac, Emmanuelle, Filhol, Odile, Barette, Caroline, Giacosa, Sofia
Year of Publication 18.06.2019
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Year of Publication 18.06.2019
Patent
A Synthetic Lethal Drug Combination for Treating Renal Cell Carcinoma
Cochet, Claude, Pillet, Catherine, Soleilhac, Emmanuelle, Filhol, Odile, Barette, Caroline, Giacosa, Sofia
Year of Publication 13.09.2018
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Year of Publication 13.09.2018
Patent
A SYNTHETIC LETHAL DRUG COMBINATION FOR TREATING RENAL CELL CARCINOMA
SOLEILHAC, Emmanuelle, BARETTE, Caroline, COCHET, Claude, PILLET, Catherine, FILHOL, Odile, GIACOSA, Sofia
Year of Publication 01.08.2018
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Year of Publication 01.08.2018
Patent
HETEROCYCLIC NAPHTHOQUINONES DERIVATIVES FOR USE IN THE TREATMENT OF CANCERS INCLUDING CUSHING DISEASE
SOLEILHAC, Emmanuelle, TERME, Thierry, VANELLE, Patrice, REMUSAT, Vincent, BARETTE, Caroline, FAUVARQUE, Marie-Odile, AGUILAR, Carmen, MORTIER, Magda, PILLET, Catherine
Year of Publication 19.06.2019
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Year of Publication 19.06.2019
Patent
Heterocyclic Naphthoquinones Derivatives for Use in the Treatment of Cancers Including Cushing Disease
Pillet, Catherine, Soleilhac, Emmanuelle, Vanelle, Patrice, Barette, Caroline, Remusat, Vincent, Mortier, Magda, Aguilar, Carmen, Terme, Thierry, Fauvarque, Marie-Odile
Year of Publication 06.06.2019
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Year of Publication 06.06.2019
Patent
A SYNTHETIC LETHAL DRUG COMBINATION FOR TREATING RENAL CELL CARCINOMA
SOLEILHAC, Emmanuelle, BARETTE, Caroline, COCHET, Claude, PILLET, Catherine, FILHOL-COCHET, Odile, GIACOSA, Sofia
Year of Publication 26.04.2017
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Year of Publication 26.04.2017
Patent