Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients
Fey, Dirk, Halasz, Melinda, Dreidax, Daniel, Kennedy, Sean P, Hastings, Jordan F, Rauch, Nora, Munoz, Amaya Garcia, Pilkington, Ruth, Fischer, Matthias, Westermann, Frank, Kolch, Walter, Kholodenko, Boris N, Croucher, David R
Published in Science signaling (22.12.2015)
Published in Science signaling (22.12.2015)
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Journal Article
Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways
Rodriguez, Javier, Pilkington, Ruth, Garcia Munoz, Amaya, Nguyen, Lan K., Rauch, Nora, Kennedy, Susan, Monsefi, Naser, Herrero, Ana, Taylor, Cormac T., von Kriegsheim, Alex
Published in Cell reports (Cambridge) (22.03.2016)
Published in Cell reports (Cambridge) (22.03.2016)
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Journal Article
On-beads digestion in conjunction with data-dependent mass spectrometry: a shortcut to quantitative and dynamic interaction proteomics
Turriziani, Benedetta, Garcia-Munoz, Amaya, Pilkington, Ruth, Raso, Cinzia, Kolch, Walter, von Kriegsheim, Alexander
Published in Biology (Basel, Switzerland) (16.04.2014)
Published in Biology (Basel, Switzerland) (16.04.2014)
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Journal Article
Activation of MMP-9 by human lung epithelial cells in response to the cystic fibrosis-associated pathogen Burkholderia cenocepacia reduced wound healing in vitro
Wright, Ciara, Pilkington, Ruth, Callaghan, Máire, McClean, Siobhán
Published in American journal of physiology. Lung cellular and molecular physiology (01.10.2011)
Published in American journal of physiology. Lung cellular and molecular physiology (01.10.2011)
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Journal Article
The Relational Value of Professional Dialogue for Academics Pursuing HEA Fellowship
Asghar, Mandy, Pilkington, Ruth
Published in The international journal for academic development (03.04.2018)
Published in The international journal for academic development (03.04.2018)
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Journal Article
Guided versus blind liver biopsy for chronic hepatitis C: clinical benefits and costs
Farrell, Richard J, Smiddy, Pauline F, Pilkington, Ruth M, Tobin, Anne A, Mooney, Eoghan E, Temperley, Ian J, McDonald, George S, Bowmer, Heather A, Wilson, Graham F, Kelleher, Dermot
Published in Journal of hepatology (01.04.1999)
Published in Journal of hepatology (01.04.1999)
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Journal Article
Phosphorylation of RAF Kinase Dimers Drives Conformational Changes that Facilitate Transactivation
Jambrina, Pablo G., Rauch, Nora, Pilkington, Ruth, Rybakova, Katja, Nguyen, Lan K., Kholodenko, Boris N., Buchete, Nicolae-Viorel, Kolch, Walter, Rosta, Edina
Published in Angewandte Chemie International Edition (18.01.2016)
Published in Angewandte Chemie International Edition (18.01.2016)
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Journal Article
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Kennedy, Susan A., Jarboui, Mohamed-Ali, Srihari, Sriganesh, Raso, Cinzia, Bryan, Kenneth, Dernayka, Layal, Charitou, Theodosia, Bernal-Llinares, Manuel, Herrera-Montavez, Carlos, Krstic, Aleksandar, Matallanas, David, Kotlyar, Max, Jurisica, Igor, Curak, Jasna, Wong, Victoria, Stagljar, Igor, LeBihan, Thierry, Imrie, Lisa, Pillai, Priyanka, Lynn, Miriam A., Fasterius, Erik, Al-Khalili Szigyarto, Cristina, Breen, James, Kiel, Christina, Serrano, Luis, Rauch, Nora, Rukhlenko, Oleksii, Kholodenko, Boris N., Iglesias-Martinez, Luis F., Ryan, Colm J., Pilkington, Ruth, Cammareri, Patrizia, Sansom, Owen, Shave, Steven, Auer, Manfred, Horn, Nicola, Klose, Franziska, Ueffing, Marius, Boldt, Karsten, Lynn, David J., Kolch, Walter
Published in Nature communications (24.01.2020)
Published in Nature communications (24.01.2020)
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Journal Article
The tyrosine kinase BceF and the phosphotyrosine phosphatase BceD of Burkholderia contaminans are required for efficient invasion and epithelial disruption of a cystic fibrosis lung epithelial cell line
Ferreira, Ana S, Silva, Inês N, Fernandes, Fábio, Pilkington, Ruth, Callaghan, Máire, McClean, Siobhán, Moreira, Leonilde M
Published in Infection and immunity (01.02.2015)
Published in Infection and immunity (01.02.2015)
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Journal Article
Interaction of environmental Burkholderia cenocepacia strains with cystic fibrosis and non-cystic fibrosis bronchial epithelial cells in vitro
BEVIVINO, Annamaria, PIRONE, Luisa, PILKINGTON, Ruth, CIFANI, Noemi, DALMASTRI, Claudia, CALLAGHAN, Máire, ASCENZIONI, Fiorentina, MCCLEAN, Siobhán
Published in Microbiology (Society for General Microbiology) (01.05.2012)
Published in Microbiology (Society for General Microbiology) (01.05.2012)
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Journal Article
Abstract CN05-03: Personalized cancer diagnostics and therapeutics based on the computational modeling of signal transduction networks
Kolch, Walter, Fey, Dirk, Halasz, Melinda, Rauch, Nora, Munoz, Amaya Garcia, Pilkington, Ruth, Kholodenko, Boris N., Croucher, David R., Kennedy, Sean P., Hastings, Jordan F., Westermann, Frank, Dreidax, Daniel, Fischer, Matthias, Duffy, David, Krstic, Aleksandar, Schwarzl, Thomas
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Journal Article
Activation of MMP-9 by human lung epithelial cells in response to the cystic fibrosis-associated pathogen Burkholderia cenocepacia reduced wound healing in vitro
WRIGHT, Ciara, PILKINGTON, Ruth, CALLAGHAN, Máire, MCCLEAN, Siobhán
Published in American journal of physiology. Lung cellular and molecular physiology (2011)
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Published in American journal of physiology. Lung cellular and molecular physiology (2011)
Journal Article
Death and dignity through fresh eyes
Phillips, Matthew, Pilkington, Ruth, Patterson, Aileen, Hennessy, Martina
Published in The clinical teacher (01.12.2011)
Published in The clinical teacher (01.12.2011)
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Journal Article
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRAS G13D
Kennedy, Susan A, Jarboui, Mohamed-Ali, Srihari, Sriganesh, Raso, Cinzia, Bryan, Kenneth, Dernayka, Layal, Charitou, Theodosia, Bernal-Llinares, Manuel, Herrera-Montavez, Carlos, Krstic, Aleksandar, Matallanas, David, Kotlyar, Max, Jurisica, Igor, Curak, Jasna, Wong, Victoria, Stagljar, Igor, LeBihan, Thierry, Imrie, Lisa, Pillai, Priyanka, Lynn, Miriam A, Fasterius, Erik, Al-Khalili Szigyarto, Cristina, Breen, James, Kiel, Christina, Serrano, Luis, Rauch, Nora, Rukhlenko, Oleksii, Kholodenko, Boris N, Iglesias-Martinez, Luis F, Ryan, Colm J, Pilkington, Ruth, Cammareri, Patrizia, Sansom, Owen, Shave, Steven, Auer, Manfred, Horn, Nicola, Klose, Franziska, Ueffing, Marius, Boldt, Karsten, Lynn, David J, Kolch, Walter
Published in Nature communications (24.01.2020)
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Published in Nature communications (24.01.2020)
Journal Article
Chronic hepatitis C infection and sicca syndrome: a clear association with HLA DQB102
Smyth, Claire M, McKiernan, Susan M, Hagan, Richard, Pilkington, Ruth, O'Regan, Myra, Lawlor, Emer, Kelleher, Dermot
Published in European journal of gastroenterology & hepatology (01.06.2007)
Published in European journal of gastroenterology & hepatology (01.06.2007)
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