The Comprehensive in Vitro Proarrhythmia Assay (CiPA) initiative — Update on progress
Colatsky, Thomas, Fermini, Bernard, Gintant, Gary, Pierson, Jennifer B., Sager, Philip, Sekino, Yuko, Strauss, David G., Stockbridge, Norman
Published in Journal of pharmacological and toxicological methods (01.09.2016)
Published in Journal of pharmacological and toxicological methods (01.09.2016)
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Journal Article
Can non‐clinical repolarization assays predict the results of clinical thorough QT studies? Results from a research consortium
Park, Eunjung, Gintant, Gary A, Bi, Daoqin, Kozeli, Devi, Pettit, Syril D, Pierson, Jennifer B, Skinner, Matthew, Willard, James, Wisialowski, Todd, Koerner, John, Valentin, Jean‐Pierre
Published in British journal of pharmacology (01.02.2018)
Published in British journal of pharmacology (01.02.2018)
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Journal Article
Can We Panelize Seizure?
Roberts, Ruth, Authier, Simon, Mellon, R Daniel, Morton, Michael, Suzuki, Ikuro, Tjalkens, Ronald B, Valentin, Jean-Pierre, Pierson, Jennifer B
Published in Toxicological sciences (06.01.2021)
Published in Toxicological sciences (06.01.2021)
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Journal Article
Non-Lethal Endotoxin Injection: A Rat Model of Hypercoagulability
Brooks, Marjory B, Turk, James R, Guerrero, Abraham, Narayanan, Padma K, Nolan, John P, Besteman, Elizabeth G, Wilson, Dennis W, Thomas, Roberta A, Fishman, Cindy E, Thompson, Karol L, Ellinger-Ziegelbauer, Heidrun, Pierson, Jennifer B, Paulman, April, Chiang, Alan Y, Schultze, Albert E
Published in PloS one (12.01.2017)
Published in PloS one (12.01.2017)
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Journal Article
Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes
Ribeiro, Alexandre J. S., Guth, Brian D., Engwall, Michael, Eldridge, Sandy, Foley, C. Michael, Guo, Liang, Gintant, Gary, Koerner, John, Parish, Stanley T., Pierson, Jennifer B., Brock, Mathew, Chaudhary, Khuram W., Kanda, Yasunari, Berridge, Brian
Published in Frontiers in pharmacology (29.08.2019)
Published in Frontiers in pharmacology (29.08.2019)
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Journal Article
Considerations for an In Vitro , Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms
Guth, Brian D, Engwall, Michael, Eldridge, Sandy, Foley, C Michael, Guo, Liang, Gintant, Gary, Koerner, John, Parish, Stanley T, Pierson, Jennifer B, Ribeiro, Alexandre J S, Zabka, Tanja, Chaudhary, Khuram W, Kanda, Yasunari, Berridge, Brian
Published in Frontiers in pharmacology (09.08.2019)
Published in Frontiers in pharmacology (09.08.2019)
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Journal Article
Detection of contractility changes in the heart from arterial blood pressure data using symmetric Projection Attractor Reconstruction
Bonet-Luz, Esther, Nandi, Manasi, Christie, Mark I., Doyle, Jennifer, Pierson, Jennifer B., Pugsley, Michael K., Vargas, Hugo M., Aston, Philip J.
Published in Journal of pharmacological and toxicological methods (01.09.2024)
Published in Journal of pharmacological and toxicological methods (01.09.2024)
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Journal Article
Collaborative science in action: A 20 year perspective from the Health and Environmental Sciences Institute (HESI) Cardiac Safety Committee
Pierson, Jennifer B., Berridge, Brian, Blinova, Ksenia, Brooks, Marjory B., Eldridge, Sandy, O'Brien, Claire E., Pugsley, Michael K., Schultze, A. Eric, Smith, Godfrey, Stockbridge, Norman, Valentin, Jean-Pierre, Vicente, Jose
Published in Journal of pharmacological and toxicological methods (01.05.2024)
Published in Journal of pharmacological and toxicological methods (01.05.2024)
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Journal Article
The incidence of spontaneous arrhythmias in telemetered beagle dogs, Göttingen Minipigs and Cynomolgus non-human primates: A HESI consortium retrospective analysis
Boulay, Emmanuel, Miraucourt, Loïs S., Pugsley, Michael K., Abernathy, Matthew M., Chui, Ray, Dalton, Jill, Demers, Marjorie, Dybdal, Noel, Gazaille, Elissa, Greiter-Wilke, Andrea, Hoffmann, Peter, Huang, Hai, LaDuke, Carrie, Norton, Kevin, Pierson, Jennifer B., Reeves, Isabelle, Roche, Brian, Rossman, Eric I., Schultze, Albert E., Tang, Hai-Ming, Wisialowski, Todd, Authier, Simon
Published in Journal of pharmacological and toxicological methods (01.05.2023)
Published in Journal of pharmacological and toxicological methods (01.05.2023)
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Journal Article
Use of the ZDF rat to model dietary fat induced hypercoagulability is limited by progressive and fatal nephropathy
Pugsley, Michael K., Brooks, Marjory B., Fishman, Cindy E., Katavolos, Paula, Chiang, Alan Y., Parish, Stanley T., Pierson, Jennifer B., Schultze, Albert E.
Published in Journal of pharmacological and toxicological methods (01.01.2021)
Published in Journal of pharmacological and toxicological methods (01.01.2021)
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Journal Article
Changes in the metabolome and microRNA levels in biological fluids might represent biomarkers of neurotoxicity: A trimethyltin study
Imam, Syed Z, He, Zhen, Cuevas, Elvis, Rosas-Hernandez, Hector, Lantz, Susan M, Sarkar, Sumit, Raymick, James, Robinson, Bonnie, Hanig, Joseph P, Herr, David, MacMillan, Denise, Smith, Aaron, Liachenko, Serguei, Ferguson, Sherry, O’Callaghan, James, Miller, Diane, Somps, Christopher, Pardo, Ingrid D, Slikker Jr, William, B Pierson, Jennifer, Roberts, Ruth, Gong, Binsheng, Tong, Weida, Aschner, Michael, J Kallman, Mary, Calligaro, David, Paule, Merle G
Published in Experimental biology and medicine (Maywood, N.J.) (01.02.2018)
Published in Experimental biology and medicine (Maywood, N.J.) (01.02.2018)
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Journal Article
Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation
Rossman, Eric I., Cools, Frank, Cordes, Jason, Dhuyvetter, Deborah, Doyle, Jennifer M., Friedrichs, Gregory S., Guth, Brian, Neradilek, Moni B., Parish, Stanley T., Pierson, Jennifer B., Polissar, Nayak, Tang, Hai-Ming
Published in Journal of pharmacological and toxicological methods (01.09.2020)
Published in Journal of pharmacological and toxicological methods (01.09.2020)
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Journal Article
Evaluating uncertainty to strengthen epidemiologic data for use in human health risk assessments
Burns, Carol J, Wright, J Michael, Pierson, Jennifer B, Bateson, Thomas F, Burstyn, Igor, Goldstein, Daniel A, Klaunig, James E, Luben, Thomas J, Mihlan, Gary, Ritter, Leonard, Schnatter, A Robert, Symons, J Morel, Yi, Kun Don
Published in Environmental health perspectives (01.11.2014)
Published in Environmental health perspectives (01.11.2014)
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Journal Article
A public–private consortium advances cardiac safety evaluation: Achievements of the HESI Cardiac Safety Technical Committee
Pierson, Jennifer B., Berridge, Brian R., Brooks, Marjory B., Dreher, Kevin, Koerner, John, Schultze, A. Eric, Sarazan, R. Dustan, Valentin, Jean-Pierre, Vargas, Hugo M., Pettit, Syril D.
Published in Journal of pharmacological and toxicological methods (01.07.2013)
Published in Journal of pharmacological and toxicological methods (01.07.2013)
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Journal Article
Circulating biomarkers of neurotoxicity: Proteomics approach reveals fluidic endpoints of central nervous system toxicity in a rodent model of neurotoxicity
Imam, Syed, He, Zhen, Rogstad, Sarah, Burks, Susan, Raymick, James, Robinson, Bonnie, Cuevas, Elvis, Sarkar, Sumit, Law, Charles, Hanig, Joseph, Herr, David, MacMillan, Denise, Smith, Aaron, Liachenko, Serguei, O'Callaghan, James, Somps, Christopher, Pardo, Ingrid, Pierson, Jennifer B., Roberts, Ruth, Gong, Binsheng, Tong, Weida, Aschner, Michael, Kallman, Mary Jeanne, Ferguson, Sherry, Paule, Merle, Slikker, William
Published in Journal of pharmacological and toxicological methods (01.09.2021)
Published in Journal of pharmacological and toxicological methods (01.09.2021)
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Journal Article
Health and environmental sciences institute integrated strategies working group: Update on the evaluation of drug-induced changes in the cardiac inotropy in dogs
Engwall, Michael J., Walisser, Jacqueline A., Saul, Jim, Dustan Sarazan, R., Guth, Brian, Market, Michael, Skinner, Matthew, Guillon, Jean-Michel, Ottinger, Sean, Heyen, Jonathan R., Cools, Frank, Hoffmann, Peter K., Rossman, Eric I., Pierson, Jennifer B.
Published in Journal of pharmacological and toxicological methods (01.11.2014)
Published in Journal of pharmacological and toxicological methods (01.11.2014)
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Journal Article
A publicaprivate consortium advances cardiac safety evaluation: Achievements of the HESI Cardiac Safety Technical Committee
Pierson, Jennifer B, Berridge, Brian R, Brooks, Marjory B, Dreher, Kevin, Koerner, John, Schultze, AEric, Sarazan, RDustan, Valentin, Jean-Pierre, Vargas, Hugo M, Pettit, Syril D
Published in Journal of pharmacological and toxicological methods (01.08.2013)
Published in Journal of pharmacological and toxicological methods (01.08.2013)
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Journal Article