Peripheral and intrahepatic virological phenotyping in eAg negative chronic hepatitis B to evaluate risk of disease progression and hepatocellular carcinoma in the “grey-zone” viral load cohort
Svicher, V, Salpini, R, Colagrossi, L, Battisti, A, Piermatteo, L, Hansi, N, Perno, C.F, Gill, U.S, Kennedy, P.T.F
Published in Journal of hepatology (2017)
Published in Journal of hepatology (2017)
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Journal Article
The circulation of specific vaccine-escape HBsAg mutations in HBV genotype D infected patients correlates with high viremia and affects HBsAg detection and quantification
Salpini, R, Piermatteo, L, Di Carlo, D, Battisti, A, Colagrossi, L, Bertoli, A, Fabeni, L, Fini, V, Iuvara, A, Ricciardi, A, Cerva, C, Sarrecchia, C, Lichtner, M, Mastroianni, C, De Sanctis, G, Paoloni, M, Marignani, M, Pasquazzi, C, Iapadre, N, Mari, T, Parruti, G, Romano, S, Visca, M, Moretti, A, Vecchiet, J, Sarmati, L, Andreoni, M, Cappiello, G, Spanò, A, Grelli, S, Angelico, M, Perno, C.F, Svicher, V
Published in Journal of hepatology (2017)
Published in Journal of hepatology (2017)
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Journal Article
In HBeAg-negative chronic HBV infection, HBsAg levels profoundly vary among different HBV-genotypes and can be influenced by the degree of HBsAg variability: can quantitative HBsAg truly reflect intra-hepatic HBV reservoir?
Salpini, R, Battisti, A, Anastasiou, O, Gill, U, Colagrossi, L, Bertoli, A, Fabeni, L, Fini, V, Piermatteo, L, Iuvara, A, Malagnino, V, Cerva, C, Lichtner, M, Mastroianni, C, De Sanctis, G, Paoloni, M, Marignani, M, Pasquazzi, C, Iapadre, N, Mari, T, Parruti, G, Vecchiet, J, Sarmati, L, Andreoni, M, Angelico, M, Grelli, S, Kennedy, P, Verheyen, J, Perno, C.F, Svicher, V
Published in Journal of hepatology (2017)
Published in Journal of hepatology (2017)
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Journal Article
Hepatitis Delta Antigen (HDAg) is characterized by an extensive degree of genetic variability that correlates with elevated levels of serum HDV-RNA
Colagrossi, L, Salpini, R, Scutari, R, Battisti, A, Piermatteo, L, Bertoli, A, Menichini, C, Trimoulet, P, Fleury, H, Nebuloso, E, De Cristofaro, M, Cappiello, G, Spanò, A, Malagnino, V, Mari, T, Barlattani, A, Iapadre, N, Lichtner, M, Mastroianni, C.M, Lenci, I, Pasquazzi, C, De Sanctis, G.M, Lanza, A.G, Stanzione, M, Stornaiuolo, G, Marignani, M, Sarmati, L, Andreoni, M, Angelico, M, Perno, C.F, Coppola, N, Svicher, V
Published in Journal of hepatology (2017)
Published in Journal of hepatology (2017)
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Journal Article
Gain of positively charged amino acids at specific positions of HBsAg C-terminus tightly correlates with HBV-induced hepatocellular carcinoma by altering the structural folding of this domain
Salpini, R, Carioti, L, Aragri, M, Di Carlo, D, Colagrossi, L, Battisti, A, Piermatteo, L, Bertoli, A, Fabeni, L, Ricciardi, A, Longo, R, Romano, S, Cappiello, G, Spanò, A, Trimoulet, P, Fleury, H, Vecchiet, J, Iapadre, N, Barlattani, A, Mari, T, Pasquazzi, C, Lenci, I, Francioso, S, Parruti, G, Sarmati, L, Andreoni, M, Angelico, M, Ceccherini-Silberstein, F, Perno, C.F, Svicher, V
Published in Journal of hepatology (2017)
Published in Journal of hepatology (2017)
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Journal Article
In HBeAg-negative chronic HBV infection, HBsAg levels profoundly differ among HBV-genotypes and can be affected by the extent of HBsAg variability: Can quantitative HBsAg truly reflect intra-hepatic HBV reservoir?
Salpini, R, Battisti, A, Anastasiou, O, Gill, U, Colagrossi, L, Bertoli, A, Fabeni, L, Fini, V, Piermatteo, L, Iuvara, A, Malagnino, V, Cerva, C, Lichtner, M, Mastroianni, C, De Sanctis, G, Paoloni, M, Marignani, M, Pasquazzi, C, Iapadre, N, Mari, T, Parruti, G, Vecchiet, I, Sarmati, L, Andreoni, M, Angelico, M, Grelli, S, Kennedy, P, Verheyen, J, Perno, C.-F, Svicher, V
Published in Digestive and liver disease (16.02.2017)
Published in Digestive and liver disease (16.02.2017)
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Journal Article
Kinetics of the three HBsAg forms along with HDV-RNA predict virological and biochemical responses in chronic hepatitis delta patients treated with bulevirtide for 48 weeks
D'Anna, S., Salpini, R., Degasperi, E., Duca, L., Anolli, M.P., Piermatteo, L., Sambarino, D., Borghi, M., Facchetti, F., Ceccherini-Silberstein, F., Perbellini, R., Lampertico, P., Svicher, V.
Published in Digestive and liver disease (01.02.2024)
Published in Digestive and liver disease (01.02.2024)
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Journal Article
Serum HBsAg and ddPCR HBV-DNA as predictive parameters of HBsAg loss after nucleo(s)tide analogue (NA) treatment discontinuation in non-cirrhotic patients with Chronic Hepatitis B
Guerra, A.F., Tomassoli, G., Piermatteo, L., D'Anna, S., Salpini, R., Svicher, V., Abbati, G., Pietrangelo, A., Ventura, P.
Published in Digestive and liver disease (01.03.2022)
Published in Digestive and liver disease (01.03.2022)
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Journal Article
Pathways sustaining HDV activity act independently from the size of HBV resevoir and are fueled by an abundant expression of HBsAg from integrated HBV-DNA
Salpini, R., D'Anna, S., Piermatteo, L., Teti, E., Di Lorenzo, A., Brancaccio, G., Torre, G., Malagnino, V., Iannetta, M., Ceccherini-Silberstein, F., Pasquazzi, C., Cillo, U., Vitale, A., Gringeri, E., Magrofuoco, M., Pacenti, M., Baiocchi, L., Francioso, S., Lenci, I., Geretti, A.M., Abate, M.L., Olivero, A., Gaeta, G.B., Sarmati, L., Rizzetto, M., Caviglia, G.P., Svicher, V.
Published in Digestive and liver disease (01.02.2024)
Published in Digestive and liver disease (01.02.2024)
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Journal Article
HDV epidemic in Central Italy is stable over the last two decades and is characterized by the circulation of multiple HDV sub-genotypes 1 inducing different inflammatory stimuli
Salpini, R., Piermatteo, L., Torre, G., D'Anna, S., Khan, S., Duca, L., Bertoli, A., Malagnino, V., Paba, P., Ciotti, M., Lenci, I., Francioso, S., Paquazzi, C., Lichtner, M., Mastroianni, C., Santopaolo, F., De Sanctis, G., Marignani, M., Pellicelli, A., Galati, G., Moretti, A., Colucci, G., Casinelli, K., Caterini, L., Iapadre, N., Parruti, G., Vecchiet, I., Paoloni, M., Grelli, S., Ceccherini-Silberstein, F., Sarmati, L., Svicher, V.
Published in Digestive and liver disease (01.03.2023)
Published in Digestive and liver disease (01.03.2023)
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Journal Article
FRI-261 - The levels of middle surface HBVantigen increase in patients with HBV-driven liver cancer despite prolonged virological suppression: implications for a novel marker of HBV-driven hepatocarcinogenesis
Brancaccio, G., Salpini, R., Colagrossi, L., Fini, V., Cantone, M., Battisti, A., Piermatteo, L., Oda, Y., Perno, C.F., Gaeta, G.B., Svicher, V.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
FRI-272 - Combination of HBV serological markers to predict the burden and productivity of intrahepatic HBV reservoir and disease progression in HBeAg negative Chronic Hepatitis B
Svicher, V., Salpini, R., Colagrossi, L., Carlo, D.D., Battisti, A., Piermatteo, L., Hansi, N., Silberstein, F.C., Perno, C.F., Gill, U.S., Kennedy, P.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
Combination of HBV serological markers to predict the burden and productivity of intrahepatic HBV reservoir and disease progression in HBeAg negative Chronic Hepatitis B
Svicher, V., Salpini, R., Colagrossi, L., Carlo, D.D., Battisti, A., Piermatteo, L., Hansi, N., Silberstein, F.C., Perno, C.F., Gill, U.S., Kennedy, P.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
The levels of middle surface HBVantigen increase in patients with HBV-driven liver cancer despite prolonged virological suppression: implications for a novel marker of HBV-driven hepatocarcinogenesis
Brancaccio, G., Salpini, R., Colagrossi, L., Fini, V., Cantone, M., Battisti, A., Piermatteo, L., Oda, Y., Perno, C.F., Gaeta, G.B., Svicher, V.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
Basal core promoter mutations as potential predictors of an enlarged intrahepatic HBV reservoir and enhanced cccDNA transcriptional activity in HBeAg negative chronic hepatitis B infection
Colagrossi, L., Salpini, R., Gill, U.S., Battisti, A., Piermatteo, L., Carlo, D.D., Hansi, N., Silberstein, F.C., Perno, C.F., Kennedy, P., Svicher, V.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
FRI-277 - Basal core promoter mutations as potential predictors of an enlarged intrahepatic HBV reservoir and enhanced cccDNA transcriptional activity in HBeAg negative chronic hepatitis B infection
Colagrossi, L., Salpini, R., Gill, U.S., Battisti, A., Piermatteo, L., Carlo, D.D., Hansi, N., Silberstein, F.C., Perno, C.F., Kennedy, P., Svicher, V.
Published in Journal of hepatology (01.04.2018)
Published in Journal of hepatology (01.04.2018)
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Journal Article
SAT-186 - Peripheral and intrahepatic virological phenotyping in eAg negative chronic hepatitis B to evaluate risk of disease progression and hepatocellular carcinoma in the “grey-zone” viral load cohort
Svicher, V., Salpini, R., Colagrossi, L., Battisti, A., Piermatteo, L., Hansi, N., Perno, C.F., Gill, U.S., Kennedy, P.T.F.
Published in Journal of hepatology (2017)
Published in Journal of hepatology (2017)
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Journal Article
Combination of HBV serological markers can predict the burden and productivity of intrahepatic HBV reservoir and disease progression in HBeAg-negative chronic hepatitis B infection
Salpini, R., Colagrossi, L., Gill, U.S., Battisti, A., Piermatteo, L., Hansi, N., Perno, C.F., Kennedy, P.T.F., Svicher, V.
Published in Digestive and liver disease (01.02.2018)
Published in Digestive and liver disease (01.02.2018)
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Journal Article
A close monitoring of virological and immunological hepatitis B markers can improve the diagnosis of HBV reactivation in HBsAg-negative/anti-HBc-positive patients with oncohematological diseases
Salpini, R., Cerva, C., Battisti, A., Piermatteo, L., Sacco, A., Malagnino, V., Arcese, W., Cantonetti, M., Ceccherini-Silberstein, F., Perno, C.F., Andreoni, M., Sarmati, L., Svicher, V.
Published in Digestive and liver disease (01.02.2019)
Published in Digestive and liver disease (01.02.2019)
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Journal Article
The combined usage of accurate virological and serological HBV markers can help to identify HBsAg-negative/anti-HBc-positive patients at higher risk of HBV-reactivation and to optimize prophylaxis duration in oncohematological setting
Salpini, R., Alkhatib, M., Cerva, C., Piermatteo, L., Battisti, A., Malagnino, V., Fabeni, L, Cantonetti, M.L., Arcese, W., Ceccherini-Silberstein, F., Perno, C.F., Andreoni, M., Sarmati, L., Svicher, V.
Published in Digestive and liver disease (01.02.2020)
Published in Digestive and liver disease (01.02.2020)
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Journal Article