GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function
Kumar, Anmol, Kopra, Jaakko, Varendi, Kärt, Porokuokka, Lauriina L, Panhelainen, Anne, Kuure, Satu, Marshall, Pepin, Karalija, Nina, Härma, Mari-Anne, Vilenius, Carolina, Lilleväli, Kersti, Tekko, Triin, Mijatovic, Jelena, Pulkkinen, Nita, Jakobson, Madis, Jakobson, Maili, Ola, Roxana, Palm, Erik, Lindahl, Maria, Strömberg, Ingrid, Võikar, Vootele, Piepponen, T Petteri, Saarma, Mart, Andressoo, Jaan-Olle
Published in PLoS genetics (01.12.2015)
Published in PLoS genetics (01.12.2015)
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Inactivation of the GATA Cofactor ZFPM1 Results in Abnormal Development of Dorsal Raphe Serotonergic Neuron Subtypes and Increased Anxiety-Like Behavior
Tikker, Laura, Casarotto, Plinio, Singh, Parul, Biojone, Caroline, Piepponen, T Petteri, Estartús, Nuri, Seelbach, Anna, Sridharan, Ravindran, Laukkanen, Liina, Castrén, Eero, Partanen, Juha
Published in The Journal of neuroscience (04.11.2020)
Published in The Journal of neuroscience (04.11.2020)
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Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson’s disease
Albert, Katrina, Voutilainen, Merja H., Domanskyi, Andrii, Piepponen, T. Petteri, Ahola, Sari, Tuominen, Raimo K., Richie, Christopher, Harvey, Brandon K., Airavaara, Mikko
Published in Journal of neuroscience research (01.03.2019)
Published in Journal of neuroscience research (01.03.2019)
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Glial cell line–derived neurotrophic factor receptor Rearranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo
Mahato, Arun Kumar, Kopra, Jaakko, Renko, Juho‐Matti, Visnapuu, Tanel, Korhonen, Ilari, Pulkkinen, Nita, Bespalov, Maxim M., Domanskyi, Andrii, Ronken, Eric, Piepponen, T. Petteri, Voutilainen, Merja H., Tuominen, Raimo K., Karelson, Mati, Sidorova, Yulia A., Saarma, Mart
Published in Movement disorders (01.02.2020)
Published in Movement disorders (01.02.2020)
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Cerebral dopamine neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice
Lindahl, Maria, Chalazonitis, Alcmène, Palm, Erik, Pakarinen, Emmi, Danilova, Tatiana, Pham, Tuan D., Setlik, Wanda, Rao, Meenakshi, Võikar, Vootele, Huotari, Jatta, Kopra, Jaakko, Andressoo, Jaan-Olle, Piepponen, Petteri T., Airavaara, Mikko, Panhelainen, Anne, Gershon, Michael D., Saarma, Mart
Published in Neurobiology of disease (01.02.2020)
Published in Neurobiology of disease (01.02.2020)
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Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson’s Disease
Huotarinen, Antti, Penttinen, Anna-Maija, Bäck, Susanne, Voutilainen, Merja H., Julku, Ulrika, Piepponen, T. Petteri, Männistö, Pekka T., Saarma, Mart, Tuominen, Raimo, Laakso, Aki, Airavaara, Mikko
Published in Neuroscience (15.03.2018)
Published in Neuroscience (15.03.2018)
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Characterization of the structural and functional determinants of MANF/CDNF in Drosophila in vivo model
Lindström, Riitta, Lindholm, Päivi, Kallijärvi, Jukka, Yu, Li-Ying, Piepponen, T Petteri, Arumäe, Urmas, Saarma, Mart, Heino, Tapio I
Published in PloS one (03.09.2013)
Published in PloS one (03.09.2013)
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Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons
Palgi, Mari, Lindström, Riitta, Peränen, Johan, Piepponen, T. Petteri, Saarma, Mart, Heino, Tapio I
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
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The overexpression of GDNF in nucleus accumbens suppresses alcohol-seeking behavior in group-housed C57Bl/6J female mice
Koskela, Maryna, Piepponen, T Petteri, Lindahl, Maria, Harvey, Brandon K, Andressoo, Jaan-Olle, Võikar, Vootele, Airavaara, Mikko
Published in Journal of biomedical science (20.12.2021)
Published in Journal of biomedical science (20.12.2021)
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Chronic 2-Fold Elevation of Endogenous GDNF Levels Is Safe and Enhances Motor and Dopaminergic Function in Aged Mice
Turconi, Giorgio, Kopra, Jaakko, Võikar, Vootele, Kulesskaya, Natalia, Vilenius, Carolina, Piepponen, T. Petteri, Andressoo, Jaan-Olle
Published in Molecular therapy. Methods & clinical development (12.06.2020)
Published in Molecular therapy. Methods & clinical development (12.06.2020)
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Increased Physiological GDNF Levels Have No Effect on Dopamine Neuron Protection and Restoration in a Proteasome Inhibition Mouse Model of Parkinson's Disease
Olfat, Soophie, Mätlik, Kärt, Kopra, Jaakko J, Garton, Daniel R, Iivanainen, Vilma H, Bhattacharya, Dipabarna, Jakobsson, Johan, Piepponen, T Petteri, Andressoo, Jaan-Olle
Published in eNeuro (01.02.2023)
Published in eNeuro (01.02.2023)
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Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson's disease
Turconi, Giorgio, Alam, Farhan, SenGupta, Tanima, Pirnes-Karhu, Sini, Olfat, Soophie, Schmidt, Mark S., Mätlik, Kärt, Montaño-Rodriguez, Ana, Heiskanen, Vladimir, Garton, Daniel, Piepponen, Petteri T., Brenner, Charles, Holmberg, Carina I., Nilsen, Hilde, Pirinen, Eija, Andressoo, Jaan-Olle
Published in Heliyon (30.07.2024)
Published in Heliyon (30.07.2024)
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Mice deficient in transmembrane prostatic acid phosphatase display increased GABAergic transmission and neurological alterations
Nousiainen, Heidi O, Quintero, Ileana B, Myöhänen, Timo T, Voikar, Vootele, Mijatovic, Jelena, Segerstråle, Mikael, Herrala, Annakaisa M, Kulesskaya, Natalia, Pulkka, Anitta E, Kivinummi, Tanja, Abo-Ramadan, Usama, Taira, Tomi, Piepponen, T Petteri, Rauvala, Heikki, Vihko, Pirkko
Published in PloS one (20.05.2014)
Published in PloS one (20.05.2014)
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Constitutive Ret Activity in Knock-In Multiple Endocrine Neoplasia Type B Mice Induces Profound Elevation of Brain Dopamine Concentration via Enhanced Synthesis and Increases the Number of TH-Positive Cells in the Substantia Nigra
Mijatovic, Jelena, Airavaara, Mikko, Planken, Anu, Auvinen, Petri, Raasmaja, Atso, Piepponen, T. Petteri, Costantini, Frank, Ahtee, Liisa, Saarma, Mart
Published in The Journal of neuroscience (02.05.2007)
Published in The Journal of neuroscience (02.05.2007)
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Characterization of the striatal dopaminergic neurotransmission in MEN2B mice with elevated cerebral tissue dopamine
Mijatovic, Jelena, Patrikainen, Outi, Yavich, Leonid, Airavaara, Mikko, Ahtee, Liisa, Saarma, Mart, Petteri Piepponen, T
Published in Journal of neurochemistry (01.06.2008)
Published in Journal of neurochemistry (01.06.2008)
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Correction: GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function
Kumar, Anmol, Kopra, Jaakko, Varendi, Kärt, Porokuokka, Lauriina L, Panhelainen, Anne, Kuure, Satu, Marshall, Pepin, Karalija, Nina, Härma, Mari-Anne, Vilenius, Carolina, Lilleväli, Kersti, Tekko, Triin, Mijatovic, Jelena, Pulkkinen, Nita, Jakobson, Madis, Jakobson, Maili, Ola, Roxana, Palm, Erik, Lindahl, Maria, Strömberg, Ingrid, Võikar, Vootele, Piepponen, T Petteri, Saarma, Mart, Andressoo, Jaan-Olle
Published in PLoS genetics (2016)
Published in PLoS genetics (2016)
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Female C57BL/6J Mice Show Alcohol-Seeking Behaviour after Withdrawal from Prolonged Alcohol Consumption in the Social Environment
Koskela, Maryna, Piepponen, T Petteri, Andressoo, Jaan-Olle, Võikar, Vootele, Airavaara, Mikko
Published in Alcohol and alcoholism (Oxford) (09.07.2022)
Published in Alcohol and alcoholism (Oxford) (09.07.2022)
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