Telaprevir for Retreatment of HCV Infection
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Published in The New England journal of medicine (23.06.2011)
Published in The New England journal of medicine (23.06.2011)
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Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study
Lawitz, Eric, Prof, Sulkowski, Mark S, Prof, Ghalib, Reem, MD, Rodriguez-Torres, Maribel, MD, Younossi, Zobair M, Prof, Corregidor, Ana, MD, DeJesus, Edwin, MD, Pearlman, Brian, Prof, Rabinovitz, Mordechai, Prof, Gitlin, Norman, MD, Lim, Joseph K, MD, Pockros, Paul J, MD, Scott, John D, MD, Fevery, Bart, MSc, Lambrecht, Tom, MSc, Ouwerkerk-Mahadevan, Sivi, PhD, Callewaert, Katleen, MSc, Symonds, William T, PharmD, Picchio, Gaston, PhD, Lindsay, Karen L, MD, Beumont, Maria, MD, Jacobson, Ira M, Prof
Published in The Lancet (British edition) (15.11.2014)
Published in The Lancet (British edition) (15.11.2014)
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TMC278, a Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor (NNRTI), Active against Wild-Type and NNRTI-Resistant HIV-1
AZIJN, Hilde, TIRRY, Ilse, VINGERHOETS, Johan, DE BETHUNE, Marie-Pierre, KRAUS, Guenter, BOVEN, Katia, JOCHMANS, Dirk, VAN CRAENENBROECK, Elke, PICCHIO, Gaston, RIMSKY, Laurence T
Published in Antimicrobial Agents and Chemotherapy (01.02.2010)
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Effect of mutations at position E138 in HIV-1 reverse transcriptase on phenotypic susceptibility and virologic response to etravirine
Tambuyzer, Lotke, Nijs, Steven, Daems, Bjorn, Picchio, Gaston, Vingerhoets, Johan
Published in Journal of acquired immune deficiency syndromes (1999) (01.09.2011)
Published in Journal of acquired immune deficiency syndromes (1999) (01.09.2011)
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Evolution of Treatment-Emergent Resistant Variants in Telaprevir Phase 3 Clinical Trials
Sullivan, James C., De Meyer, Sandra, Bartels, Doug J., Dierynck, Inge, Zhang, Eileen Z., Spanks, Joan, Tigges, Ann M., Ghys, Anne, Dorrian, Jennifer, Adda, Nathalie, Martin, Emily C., Beumont, Maria, Jacobson, Ira M., Sherman, Kenneth E., Zeuzem, Stefan, Picchio, Gaston, Kieffer, Tara L.
Published in Clinical infectious diseases (15.07.2013)
Published in Clinical infectious diseases (15.07.2013)
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Hepatitis C Virus Variants with Decreased Sensitivity to Direct-Acting Antivirals (DAAs) Were Rarely Observed in DAA-Naive Patients prior to Treatment
Bartels, Doug J, Sullivan, James C, Zhang, Eileen Z, Tigges, Ann M, Dorrian, Jennifer L, De Meyer, Sandra, Takemoto, Darin, Dondero, Elizabeth, Kwong, Ann D, Picchio, Gaston, Kieffer, Tara L
Published in Journal of Virology (01.02.2013)
Published in Journal of Virology (01.02.2013)
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Viral resistance to specifically targeted antiviral therapies for hepatitis C (STAT-Cs)
Kieffer, Tara L., Kwong, Ann D., Picchio, Gaston R.
Published in Journal of antimicrobial chemotherapy (01.02.2010)
Published in Journal of antimicrobial chemotherapy (01.02.2010)
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Efficacy and safety of etravirine in treatment-experienced, HIV-1 patients: pooled 48 week analysis of two randomized, controlled trials
KATLAMA, Christine, HAUBRICH, Richard, WOODFALL, Brian, DE SMEDT, Goedele, LALEZARI, Jacob, LAZZARIN, Adriano, MADRUGA, José V, MOLINA, Jean-Michel, SCHECHTER, Mauro, PEETERS, Monika, PICCHIO, Gaston, VINGERHOETS, Johan
Published in AIDS (London) (13.11.2009)
Published in AIDS (London) (13.11.2009)
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The HIV-1 reverse transcriptase M184I mutation enhances the E138K-associated resistance to rilpivirine and decreases viral fitness
Kulkarni, Rima, Babaoglu, Kerim, Lansdon, Eric B, Rimsky, Laurence, Van Eygen, Veerle, Picchio, Gaston, Svarovskaia, Evguenia, Miller, Michael D, White, Kirsten L
Published in Journal of acquired immune deficiency syndromes (1999) (01.01.2012)
Published in Journal of acquired immune deficiency syndromes (1999) (01.01.2012)
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Hepatitis C viral evolution in genotype 1 treatment-naïve and treatment-experienced patients receiving telaprevir-based therapy in clinical trials
Kieffer, Tara L, De Meyer, Sandra, Bartels, Doug J, Sullivan, James C, Zhang, Eileen Z, Tigges, Ann, Dierynck, Inge, Spanks, Joan, Dorrian, Jennifer, Jiang, Min, Adiwijaya, Bambang, Ghys, Anne, Beumont, Maria, Kauffman, Robert S, Adda, Nathalie, Jacobson, Ira M, Sherman, Kenneth E, Zeuzem, Stefan, Kwong, Ann D, Picchio, Gaston
Published in PloS one (12.04.2012)
Published in PloS one (12.04.2012)
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Telaprevir for Retreatment of HCV Infection
ZEUZEM, Stefan, ANDREONE, Pietro, FERENCI, Peter, NEVENS, Frederik, MÜLLHAUPT, Beat, POCKROS, Paul, TERG, Ruben, SHOUVAL, Daniel, VAN HOEK, Bart, WEILAND, Ola, VAN HEESWIJK, Rolf, DE MEYER, Sandra, POL, Stanislas, LUO, Don, BOOGAERTS, Griet, POLO, Ramon, PICCHIO, Gaston, BEUMONT, Maria, LAWITZ, Eric, DIAGO, Moises, ROBERTS, Stuart, FOCACCIA, Roberto, YOUNOSSI, Zobair, FOSTER, Graham R, HORBAN, Andrzej
Published in The New England journal of medicine (23.06.2011)
Published in The New England journal of medicine (23.06.2011)
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Prevalence in the USA of rilpivirine resistance-associated mutations in clinical samples and effects on phenotypic susceptibility to rilpivirine and etravirine
Picchio, Gaston R, Rimsky, Laurence T, Van Eygen, Veerle, Haddad, Mojgan, Napolitano, Laura A, Vingerhoets, Johan
Published in Antiviral therapy (01.01.2014)
Published in Antiviral therapy (01.01.2014)
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Establishment of B-Cell Lymphoma Cell Lines Persistently Infected with Hepatitis C Virus In Vivo and In Vitro: the Apoptotic Effects of Virus Infection
Sung, Vicky M-H, Shimodaira, Shigetaka, Doughty, Alison L, Picchio, Gaston R, Can, Huong, Yen, T S Benedict, Lindsay, Karen L, Levine, Alexandra M, Lai, Michael M C
Published in Journal of Virology (01.02.2003)
Published in Journal of Virology (01.02.2003)
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Deep-Sequencing Analysis of the Gene Encoding the Hepatitis C Virus Nonstructural 3-4A Protease Confirms a Low Prevalence of Telaprevir-Resistant Variants at Baseline and the End of the REALIZE Study
Dierynck, Inge, Thys, Kim, Ghys, Anne, Sullivan, James C., Kieffer, Tara L., Aerssens, Jeroen, Picchio, Gaston, De Meyer, Sandra
Published in The Journal of infectious diseases (15.12.2014)
Published in The Journal of infectious diseases (15.12.2014)
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Resistance profile of darunavir: combined 24-week results from the POWER trials
de Meyer, Sandra, Vangeneugden, Tony, van Baelen, Ben, de Paepe, Els, van Marck, Herwig, Picchio, Gaston, Lefebvre, Eric, de Béthune, Marie-Pierre
Published in AIDS research and human retroviruses (01.03.2008)
Published in AIDS research and human retroviruses (01.03.2008)
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Telaprevir Activity in Treatment-Naive Patients Infected Hepatitis C Virus Genotype 4: A Randomized Trial
Benhamou, Yves, Moussalli, Joseph, Ratziu, Vlad, Lebray, Pascal, De Backer, Katrien, De Meyer, Sandra, Ghys, Anne, Luo, Donghan, Picchio, Gaston R., Beumont, Maria
Published in The Journal of infectious diseases (15.09.2013)
Published in The Journal of infectious diseases (15.09.2013)
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Deep sequencing analysis of HIV-1 reverse transcriptase at baseline and time of failure in patients receiving rilpivirine in the phase III studies ECHO and THRIVE
Van Eygen, Veerle, Thys, Kim, Van Hove, Carl, Rimsky, Laurence T., De Meyer, Sandra, Aerssens, Jeroen, Picchio, Gaston, Vingerhoets, Johan
Published in Journal of medical virology (01.05.2016)
Published in Journal of medical virology (01.05.2016)
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Comparative Evaluation of the Total Hepatitis C Virus Core Antigen, Branched-DNA, and Amplicor Monitor Assays in Determining Viremia for Patients with Chronic Hepatitis C during Interferon Plus Ribavirin Combination Therapy
VEILLON, Pascal, PAYAN, Christopher, PICCHIO, Gaston, MANIEZ-MONTREUIL, Michèle, GUNTZ, Philippe, LUNEL, Francoise
Published in Journal of Clinical Microbiology (01.07.2003)
Published in Journal of Clinical Microbiology (01.07.2003)
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Safety, pharmacokinetics, and antiviral activity of the capsid inhibitor AB‐506 from Phase 1 studies in healthy subjects and those with hepatitis B
Yuen, Man‐Fung, Berliba, Elina, Sukeepaisarnjaroen, Wattana, Ahn, Sang Hoon, Tanwandee, Tawesak, Lim, Young‐Suk, Kim, Yoon Jun, Poovorawan, Kittiyod, Tangkijvanich, Pisit, Schwabe, Christian, Eley, Timothy, Brown, Joanne, Lee, Amy C. H., Thi, Emily P., Paratala, Bhavna, Mani, Nagraj, Sofia, Michael J., Picchio, Gaston, Sims, Karen D., Gane, Edward J.
Published in Hepatology communications (01.12.2022)
Published in Hepatology communications (01.12.2022)
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TMC310911, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor, Shows In Vitro an Improved Resistance Profile and Higher Genetic Barrier to Resistance Compared with Current Protease Inhibitors
DIERYNCK, Inge, VAN MARCK, Herwig, VAN GINDEREN, Marcia, JONCKERS, Tim H. M, NALAM, Madhavi N. L, SCHIFFER, Celia A, RAOOF, Araz, KRAUS, Guenter, PICCHIO, Gaston
Published in Antimicrobial Agents and Chemotherapy (01.12.2011)
Published in Antimicrobial Agents and Chemotherapy (01.12.2011)
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