Sensitive, soluble chromogenic substrates for HIV-1 proteinase
RICHARDS, A. D, PHYLIP, L. H, KOSTKA, V, KAY, J, FARMERIE, W. G, SCARBOROUGH, P. E, ALVAREZ, A, DUNN, B. M, HIREL, P.-H, KONVALINKA, J, STROP, P, PAVLICKOVA, L
Published in The Journal of biological chemistry (15.05.1990)
Published in The Journal of biological chemistry (15.05.1990)
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Hydrolysis of synthetic chromogenic substrates by HIV-1 and HIV-2 proteinases
Phylip, Lowri H., Richards, Anthony D., Kay, John, Konvalinka, Jan, Strop, Peter, Blana, Ivo, Velek, Jiri, Kostka, Vladimir, Ritchie, Alison J., Broadhurst, Anne V., Farmerie, William G., Scarborough, Paula E., Dunn, Ben M.
Published in Biochemical and biophysical research communications (31.08.1990)
Published in Biochemical and biophysical research communications (31.08.1990)
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The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix
Kay, John, Gustchina, Alla, Li, Mi, Phylip, Lowri H, Lees, Wendy E, Winther, Jakob R, Dunn, Ben M, Wlodawer, Alexander
Published in Nature structural & molecular biology (01.02.2000)
Published in Nature structural & molecular biology (01.02.2000)
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Intrinsic activity of precursor forms of HIV-1 proteinase
Phylip, Lowri H., Mills, John S., Parten, Benne F., Dunn, Ben M., Kay, John
Published in FEBS letters (21.12.1992)
Published in FEBS letters (21.12.1992)
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High level expression and characterisation of Plasmepsin II, an aspartic proteinase from Plasmodium falciparum
Hill, Jeffrey, Tyas, Lorraine, Phylip, Lowri H., Kay, John, Dunn, Ben M., Berry, Colin
Published in FEBS letters (26.09.1994)
Published in FEBS letters (26.09.1994)
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Activities of precursor and tethered dimer forms of HIV proteinase
Phylip, L H, Griffiths, J T, Mills, J S, Graves, M C, Dunn, B M, Kay, J
Published in Advances in experimental medicine and biology (1995)
Published in Advances in experimental medicine and biology (1995)
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Escape mutants of HIV-1 proteinase: enzymic efficiency and susceptibility to inhibition
Wilson, Sara I, Phylip, Lowri H, Mills, John S, Gulnik, Sergei V, Erickson, John W, Dunn, Ben M, Kay, John
Published in Biochimica et biophysica acta (25.04.1997)
Published in Biochimica et biophysica acta (25.04.1997)
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The potency and specificity of the interaction between the IA3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae
Phylip, L H, Lees, W E, Brownsey, B G, Bur, D, Dunn, B M, Winther, J R, Gustchina, A, Li, M, Copeland, T, Wlodawer, A, Kay, J
Published in The Journal of biological chemistry (19.01.2001)
Published in The Journal of biological chemistry (19.01.2001)
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IA sub(3), an Aspartic Proteinase Inhibitor from Saccharomyces cerevisiae, Is Intrinsically Unstructured in Solution
Green, T B, Ganesh, O, Perry, K, Smith, L, Phylip, L H, Logan, T M, Hagen, S J, Dunn, B M, Edison, A S
Published in Biochemistry (Easton) (13.04.2004)
Published in Biochemistry (Easton) (13.04.2004)
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The Potency and Specificity of the Interaction between the IA sub(3) Inhibitor and Its Target Aspartic Proteinase from Saccharomyces cerevisiae
Phylip, L H, Lees, W E, Brownsey, B G, Bur, D, Dunn, B M, Winther, J R, Gustchina, A, Li, M, Copeland, T, Wlodawer, A, Kay, J
Published in The Journal of biological chemistry (19.01.2001)
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Published in The Journal of biological chemistry (19.01.2001)
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An unusual orientation for Tyr75 in the active site of the aspartic proteinase from Saccharomyces cerevisiae
Gustchina, Alla, Li, Mi, Phylip, Lowri H, Lees, Wendy E, Kay, John, Wlodawer, Alexander
Published in Biochemical and biophysical research communications (26.07.2002)
Published in Biochemical and biophysical research communications (26.07.2002)
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Sub-site preferences of the aspartic proteinase from the human immunodeficiency virus, HIV-1
Konvalinka, Jan, Strop, Petr, Velek, Jiri, Cerna, Vera, Kostka, Vladimir, Phylip, Lowri H., Richards, Anthony D., Dunn, Ben M., Kay, John
Published in FEBS letters (30.07.1990)
Published in FEBS letters (30.07.1990)
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Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing -hydrophobichydrophobic- or -aromaticpro- cleavage sites
Griffiths, J T, Phylip, L H, Konvalinka, J, Strop, P, Gustchina, A, Wlodawer, A, Davenport, R J, Briggs, R, Dunn, B M, Kay, J
Published in Biochemistry (Easton) (09.06.1992)
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Published in Biochemistry (Easton) (09.06.1992)
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Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing -hydrophobichydrophobic- or -aromatic super()Pro- cleavage sites
Griffiths, J T, Phylip, L H, Konvalinka, J, Strop, P, Gustchina, A, Wlodawer, A, Davenport, R J, Briggs, R, Dunn, B M, Kay, J
Published in Biochemistry (Easton) (01.01.1992)
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Published in Biochemistry (Easton) (01.01.1992)
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