Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development
Cerqueira, Débora M, Bodnar, Andrew J, Phua, Yu Leng, Freer, Rachel, Hemker, Shelby L, Walensky, Loren D, Hukriede, Neil A, Ho, Jacqueline
Published in The FASEB journal (01.08.2017)
Published in The FASEB journal (01.08.2017)
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Journal Article
Association between congenital defects in papillary outgrowth and functional obstruction in Crim1 mutant mice
Wilkinson, Lorine, Kurniawan, Nyoman D, Phua, Yu Leng, Nguyen, Michael J, Li, Joan, Galloway, Graham J, Hashitani, Hikaru, Lang, Richard J, Little, Melissa H
Published in The Journal of pathology (01.08.2012)
Published in The Journal of pathology (01.08.2012)
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Journal Article
The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development
Espiritu, Eugenel B., Crunk, Amanda E., Bais, Abha, Hochbaum, Daniel, Cervino, Ailen S., Phua, Yu Leng, Butterworth, Michael B., Goto, Toshiyasu, Ho, Jacqueline, Hukriede, Neil A., Cirio, M. Cecilia
Published in Scientific reports (30.10.2018)
Published in Scientific reports (30.10.2018)
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Journal Article
Distinct sites of renal fibrosis in Crim1 mutant mice arise from multiple cellular origins
Phua, Yu Leng, Martel, Nick, Pennisi, David J, Little, Melissa H, Wilkinson, Lorine
Published in The Journal of pathology (01.04.2013)
Published in The Journal of pathology (01.04.2013)
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Journal Article
Treatment of VLCAD-Deficient Patient Fibroblasts with Peroxisome Proliferator-Activated Receptor δ Agonist Improves Cellular Bioenergetics
D'Annibale, Olivia M, Phua, Yu Leng, Van't Land, Clinton, Karunanidhi, Anuradha, Dorenbaum, Alejandro, Mohsen, Al-Walid, Vockley, Jerry
Published in Cells (Basel, Switzerland) (24.08.2022)
Published in Cells (Basel, Switzerland) (24.08.2022)
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Journal Article
Mitochondrial ROS Triggers KIN Pathogenesis in FAN1-Deficient Kidneys
Airik, Merlin, Arbore, Haley, Childs, Elizabeth, Huynh, Amy B, Phua, Yu Leng, Chen, Chi Wei, Aird, Katherine, Bharathi, Sivakama, Zhang, Bob, Conlon, Peter, Kmoch, Stanislav, Kidd, Kendrah, Bleyer, Anthony J, Vockley, Jerry, Goetzman, Eric, Wipf, Peter, Airik, Rannar
Published in Antioxidants (01.04.2023)
Published in Antioxidants (01.04.2023)
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Journal Article
P023: The clinical utility of plasma Lyso-Gb3 in the diagnosis of Fabry disease in infants and adults
Li, Wenjiao, Stauffer, Brandon, Chen, Hongjie, Xiao, Jing, Phua, Yu Leng, Cody, Neal, Edelmann, Lisa, Kornreich, Ruth, Desnick, Robert, Yu, Chunli
Published in Genetics in Medicine Open (2023)
Published in Genetics in Medicine Open (2023)
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Journal Article
P031: Fabry disease: Genotype/phenotype correlations for 17 novel GLA mutations by GLA activity and plasma Lyso-Gb3 levels
Cody, Neal, Phua, Yu Leng, Li, Wenjiao, Nazarenko, Irina, Stauffer, Brandon, Chen, Hongjie, Xiao, Jing, Edelmann, Lisa, Kornreich, Ruth, Yu, Chunli, Desnick, Robert
Published in Genetics in Medicine Open (2023)
Published in Genetics in Medicine Open (2023)
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Journal Article
Glutamine energy substrate anaplerosis increases bone density in the Pahenu2 classical PKU mouse in the absence of phenylalanine restriction
Dobrowolski, Steven F., Phua, Yu Leng, Tourkova, Irina L., Sudano, Cayla, Vockley, Jerry, Larrouture, Quitterie C., Blair, Harry C.
Published in JIMD reports (01.09.2022)
Published in JIMD reports (01.09.2022)
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Journal Article
Persistent DNA Damage as a Driver of CKD and Tubular Cell Senescence: SA-OR57
Airik, Rannar, Airik, Merlin, Phua, Yu Leng
Published in Journal of the American Society of Nephrology (01.10.2021)
Published in Journal of the American Society of Nephrology (01.10.2021)
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Journal Article
Insights into the Regulation of Collecting Duct Homeostasis by Small Noncoding RNAs
Phua, Yu Leng, Ho, Jacqueline
Published in Journal of the American Society of Nephrology (01.02.2018)
Published in Journal of the American Society of Nephrology (01.02.2018)
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Journal Article
Phenylketonuria oxidative stress and energy dysregulation: Emerging pathophysiological elements provide interventional opportunity
Dobrowolski, Steven F., Phua, Yu Leng, Vockley, Jerry, Goetzman, Eric, Blair, Harry C.
Published in Molecular genetics and metabolism (01.06.2022)
Published in Molecular genetics and metabolism (01.06.2022)
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Journal Article
A multiomics approach reveals evidence for phenylbutyrate as a potential treatment for combined D,L-2- hydroxyglutaric aciduria
Phua, Yu Leng, D'Annibale, Olivia M., Karunanidhi, Anuradha, Mohsen, Al-Walid, Kirmse, Brian, Dobrowolski, Steven F., Vockley, Jerry
Published in Molecular genetics and metabolism (01.07.2024)
Published in Molecular genetics and metabolism (01.07.2024)
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Journal Article
Persistent DNA damage underlies tubular cell polyploidization and progression to chronic kidney disease in kidneys deficient in the DNA repair protein FAN1
Airik, Merlin, Phua, Yu Leng, Huynh, Amy B., McCourt, Blake T., Rush, Brittney M., Tan, Roderick J., Vockley, Jerry, Murray, Susan L., Dorman, Anthony, Conlon, Peter J., Airik, Rannar
Published in Kidney international (01.11.2022)
Published in Kidney international (01.11.2022)
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Journal Article
Endothelial-Derived miR-17∼92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury
Chiba, Takuto, Cerqueira, Débora M, Li, Yao, Bodnar, Andrew J, Mukherjee, Elina, Pfister, Katherine, Phua, Yu Leng, Shaikh, Kai, Sanders, Brandon T, Hemker, Shelby L, Pagano, Patrick J, Wu, Yijen L, Ho, Jacqueline, Sims-Lucas, Sunder
Published in Journal of the American Society of Nephrology (01.03.2021)
Published in Journal of the American Society of Nephrology (01.03.2021)
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Journal Article
Comparative metabolomics in the Pahenu2 classical PKU mouse identifies cerebral energy pathway disruption and oxidative stress
Dobrowolski, Steven F., Phua, Yu Leng, Sudano, Cayla, Spridik, Kayla, Zinn, Pascal O., Wang, Yudong, Bharathi, Sivakama, Vockley, Jerry, Goetzman, Eric
Published in Molecular genetics and metabolism (01.05.2022)
Published in Molecular genetics and metabolism (01.05.2022)
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Journal Article
Chromatin accessibility and microRNA expression in nephron progenitor cells during kidney development
Clugston, Andrew, Bodnar, Andrew, Cerqueira, Débora Malta, Phua, Yu Leng, Lawler, Alyssa, Boggs, Kristy, Pfenning, Andreas R., Ho, Jacqueline, Kostka, Dennis
Published in Genomics (San Diego, Calif.) (01.01.2022)
Published in Genomics (San Diego, Calif.) (01.01.2022)
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Journal Article
Phenylalanine hydroxylase deficient phenylketonuria comparative metabolomics identifies energy pathway disruption and oxidative stress
Dobrowolski, Steven F, Phua, Yu Leng, Sudano, Cayla, Spridik, Kayla, Zinn, Pascal O, Wang, Yudong, Bharathi, Sivakama, Vockley, Jerry, Goetzman, Eric
Published in Molecular genetics and metabolism (07.04.2021)
Published in Molecular genetics and metabolism (07.04.2021)
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Journal Article