A homozygous truncating mutation in PUS3 expands the role of tRNA modification in normal cognition
Shaheen, Ranad, Han, Lu, Faqeih, Eissa, Ewida, Nour, Alobeid, Eman, Phizicky, Eric M., Alkuraya, Fowzan S.
Published in Human genetics (01.07.2016)
Published in Human genetics (01.07.2016)
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Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1
Chernyakov, Irina, Whipple, Joseph M, Kotelawala, Lakmal, Grayhack, Elizabeth J, Phizicky, Eric M
Published in Genes & development (15.05.2008)
Published in Genes & development (15.05.2008)
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PUS7 mutations impair pseudouridylation in humans and cause intellectual disability and microcephaly
Shaheen, Ranad, Tasak, Monika, Maddirevula, Sateesh, Abdel-Salam, Ghada M. H., Sayed, Inas S. M., Alazami, Anas M., Al-Sheddi, Tarfa, Alobeid, Eman, Phizicky, Eric M., Alkuraya, Fowzan S.
Published in Human genetics (01.03.2019)
Published in Human genetics (01.03.2019)
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Mutations in the anticodon stem of tRNA cause accumulation and Met22-dependent decay of pre-tRNA in yeast
Payea, Matthew J, Hauke, Alayna C, De Zoysa, Thareendra, Phizicky, Eric M
Published in RNA (Cambridge) (01.01.2020)
Published in RNA (Cambridge) (01.01.2020)
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Formation of tRNA Wobble Inosine in Humans Is Disrupted by a Millennia-Old Mutation Causing Intellectual Disability
Ramos, Jillian, Han, Lu, Li, Yan, Hagelskamp, Felix, Kellner, Stefanie M., Alkuraya, Fowzan S., Phizicky, Eric M., Fu, Dragony
Published in Molecular and cellular biology (01.10.2019)
Published in Molecular and cellular biology (01.10.2019)
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A connection between the ribosome and two S. pombe tRNA modification mutants subject to rapid tRNA decay
De Zoysa, Thareendra, Hauke, Alayna C, Iyer, Nivedita R, Marcus, Erin, Ostrowski, Sarah M, Stegemann, Franziska, Ermolenko, Dmitri N, Fay, Justin C, Phizicky, Eric M
Published in PLoS genetics (31.01.2024)
Published in PLoS genetics (31.01.2024)
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Rapid tRNA Decay Can Result from Lack of Nonessential Modifications
Alexandrov, Andrei, Chernyakov, Irina, Gu, Weifeng, Hiley, Shawna L., Hughes, Timothy R., Grayhack, Elizabeth J., Phizicky, Eric M.
Published in Molecular cell (06.01.2006)
Published in Molecular cell (06.01.2006)
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Identification of the determinants of tRNA function and susceptibility to rapid tRNA decay by high-throughput in vivo analysis
Guy, Michael P, Young, David L, Payea, Matthew J, Zhang, Xiaoju, Kon, Yoshiko, Dean, Kimberly M, Grayhack, Elizabeth J, Mathews, David H, Fields, Stanley, Phizicky, Eric M
Published in Genes & development (01.08.2014)
Published in Genes & development (01.08.2014)
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