Mitoxantrone, More than Just Another Topoisomerase II Poison
Evison, Benny J., Sleebs, Brad E., Watson, Keith G., Phillips, Don R., Cutts, Suzanne M.
Published in Medicinal research reviews (01.03.2016)
Published in Medicinal research reviews (01.03.2016)
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Journal Article
Factors determining the stability, size distribution, and cellular accumulation of small, monodisperse chitosan nanoparticles as candidate vectors for anticancer drug delivery: application to the passive encapsulation of [(14)C]-doxorubicin
Masarudin, Mas Jaffri, Cutts, Suzanne M, Evison, Benny J, Phillips, Don R, Pigram, Paul J
Published in Nanotechnology, science and applications (01.01.2015)
Published in Nanotechnology, science and applications (01.01.2015)
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Journal Article
Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death
SWIFT, Lonnie P, REPHAELI, Ada, NUDELMAN, Abraham, PHILLIPS, Don R, CUTTS, Suzanne M
Published in Cancer research (Chicago, Ill.) (01.05.2006)
Published in Cancer research (Chicago, Ill.) (01.05.2006)
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Journal Article
Activation of DNA damage response pathways as a consequence of anthracycline-DNA adduct formation
Forrest, Robert A., Swift, Lonnie P., Rephaeli, Ada, Nudelman, Abraham, Kimura, Ken-Ichi, Phillips, Don R., Cutts, Suzanne M.
Published in Biochemical pharmacology (15.06.2012)
Published in Biochemical pharmacology (15.06.2012)
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Journal Article
Potential Therapeutic Advantages of Doxorubicin when Activated by Formaldehyde to Function as a DNA Adduct-Forming Agent
Cutts, Suzanne M, Rephaeli, Ada, Nudelman, Abraham, Ugarenko, Michal, Phillips, Don R
Published in Current topics in medicinal chemistry (08.05.2015)
Published in Current topics in medicinal chemistry (08.05.2015)
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Journal Article
Encapsulation of Mitoxantrone within Cucurbit[8]uril Decreases Toxicity and Enhances Survival in a Mouse Model of Cancer
Konda, Shyam K, Maliki, Ruqaya, McGrath, Sean, Parker, Belinda S, Robinson, Tina, Spurling, Alex, Cheong, Alison, Lock, Peter, Pigram, Paul J, Phillips, Don R, Wallace, Lynne, Day, Anthony I, Collins, J. Grant, Cutts, Suzanne M
Published in ACS medicinal chemistry letters (11.05.2017)
Published in ACS medicinal chemistry letters (11.05.2017)
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Journal Article
The power and potential of doxorubicin-DNA adducts
Cutts, Suzanne M, Nudelman, Abraham, Rephaeli, Ada, Phillips, Don R
Published in IUBMB life (01.03.2005)
Published in IUBMB life (01.03.2005)
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Journal Article
Disparate impact of butyroyloxymethyl diethylphosphate (AN-7), a histone deacetylase inhibitor, and doxorubicin in mice bearing a mammary tumor
Tarasenko, Nataly, Cutts, Suzanne M, Phillips, Don R, Inbal, Aida, Nudelman, Abraham, Kessler-Icekson, Gania, Rephaeli, Ada
Published in PloS one (23.02.2012)
Published in PloS one (23.02.2012)
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Journal Article
DNA repair in response to anthracycline-DNA adducts: a role for both homologous recombination and nucleotide excision repair
Spencer, Damian M S, Bilardi, Rebecca A, Koch, Tad H, Post, Glen C, Nafie, Jordan W, Kimura, Ken-Ichi, Cutts, Suzanne M, Phillips, Don R
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (01.02.2008)
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (01.02.2008)
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Journal Article
Understanding mass spectrometry images: complexity to clarity with machine learning
Gardner, Wil, Cutts, Suzanne M., Phillips, Don R., Pigram, Paul J.
Published in Biopolymers (01.04.2021)
Published in Biopolymers (01.04.2021)
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Journal Article
Characterization of Covalent Adriamycin-DNA Adducts
Zeman, Steven M., Phillips, Don R., Crothers, Donald M.
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.1998)
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Journal Article
Development of an automated assay for accelerated in vitro detection of DNA adduct-inducing and crosslinking agents
Medan, Jelena, Sleebs, Brad E., Lackovic, Kurt, Watson, Keith G., Evison, Benny J., Phillips, Don R., Cutts, Suzanne M.
Published in Bioorganic & medicinal chemistry letters (01.03.2021)
Published in Bioorganic & medicinal chemistry letters (01.03.2021)
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Journal Article
Activation of clinically used anthracyclines by the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate
Cutts, Suzanne M, Swift, Lonnie P, Pillay, Vinochani, Forrest, Robert A, Nudelman, Abraham, Rephaeli, Ada, Phillips, Don R
Published in Molecular cancer therapeutics (01.04.2007)
Published in Molecular cancer therapeutics (01.04.2007)
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Journal Article
Formaldehyde-activated WEHI-150 induces DNA interstrand crosslinks with unique structural features
Pumuye, Paul P., Evison, Benny J., Konda, Shyam K., Collins, J. Grant, Kelso, Celine, Medan, Jelena, Sleebs, Brad E., Watson, Keith, Phillips, Don R., Cutts, Suzanne M.
Published in Bioorganic & medicinal chemistry (01.02.2020)
Published in Bioorganic & medicinal chemistry (01.02.2020)
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Journal Article
A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo
Tarasenko, Nataly, Cutts, Suzanne M., Phillips, Don R., Berkovitch-Luria, Gili, Bardugo-Nissim, Elinor, Weitman, Michal, Nudelman, Abraham, Rephaeli, Ada
Published in Biochemical pharmacology (15.03.2014)
Published in Biochemical pharmacology (15.03.2014)
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Journal Article
Isolation and structural analysis of the covalent adduct formed between a bis-amino mitoxantrone analogue and DNA: a pathway to major-minor groove cross-linked adducts
Konda, Shyam K, Kelso, Celine, Medan, Jelena, Sleebs, Brad E, Phillips, Don R, Cutts, Suzanne M, Collins, J Grant
Published in Organic & biomolecular chemistry (02.11.2016)
Published in Organic & biomolecular chemistry (02.11.2016)
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Journal Article