Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway
Skorski, Tomasz, Bellacosa, Alfonso, Nieborowska-Skorska, Margaret, Majewski, Miroslaw, Martinez, Robert, Choi, John K., Trotta, Rossana, Wlodarski, Pawel, Perrotti, Danilo, Chan, Tung O., Wasik, Mariusz A., Tsichlis, Philip N., Calabretta, Bruno
Published in The EMBO journal (15.10.1997)
Published in The EMBO journal (15.10.1997)
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Journal Article
Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation
King, Warren G., Mattaliano, Mark D., Chan, Tung O., Tsichlis, Philip N., Brugge, Joan S.
Published in Molecular and Cellular Biology (01.08.1997)
Published in Molecular and Cellular Biology (01.08.1997)
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Journal Article
Loss of ARF Sensitizes Transgenic BRAFV600E Mice to UV-Induced Melanoma via Suppression of XPC
CHI LUO, JINGHAO SHENG, HU, Miaofen G, HALUSKA, Frank G, RUTAO CUI, ZHENGPING XU, TSICHLIS, Philip N, HU, Guo-Fu, HINDS, Philip W
Published in Cancer research (Chicago, Ill.) (15.07.2013)
Published in Cancer research (Chicago, Ill.) (15.07.2013)
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Journal Article
Modulation of p47PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase
Hoyal, Carolyn R, Gutierrez, Abel, Young, Brandon M, Catz, Sergio D, Lin, Jun-Hsiang, Tsichlis, Philip N, Babior, Bernard M
Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (29.04.2003)
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Journal Article
Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells
Doan, Loretta L., Porter, Susan D., Duan, Zhijun, Flubacher, Marcella M., Montoya, Diego, Tsichlis, Philip N., Horwitz, Marshall, Gilks, C. Blake, Grimes, H. Leighton
Published in Nucleic acids research (2004)
Published in Nucleic acids research (2004)
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Journal Article
The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal
Grimes, H. Leighton, Chan, Tung O., Zweidler-McKay, Patrick A., Tong, Betty, Tsichlis, Philip N.
Published in Molecular and Cellular Biology (01.11.1996)
Published in Molecular and Cellular Biology (01.11.1996)
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Journal Article
Characterization of Phosphorylation Sites on Tpl2 Using IMAC Enrichment and a Linear Ion Trap Mass Spectrometer
Black, Terrence M, Andrews, Christine L, Kilili, Geoffrey, Ivan, Mircea, Tsichlis, Philip N, Vouros, Paul
Published in Journal of proteome research (01.06.2007)
Published in Journal of proteome research (01.06.2007)
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Journal Article
Timing Is Everything: Regulation of Cdk1 and Aneuploidy
Tsichlis, Philip N., Hatziapostolou, Maria, Hinds, Philip W.
Published in Developmental cell (01.04.2007)
Published in Developmental cell (01.04.2007)
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Journal Article
Akt, a Target of Phosphatidylinositol 3-Kinase, Inhibits Apoptosis in a Differentiating Neuronal Cell Line
Eves, Eva M., Xiong, Wen, Bellacosa, Alfonso, Kennedy, Scott G., Tsichlis, Philip N., Rosner, Marsha Rich, Hay, Nissim
Published in Molecular and Cellular Biology (01.04.1998)
Published in Molecular and Cellular Biology (01.04.1998)
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Journal Article
Defective Activation of ERK in Macrophages Lacking the p50/p105 Subunit of NF-κB Is Responsible for Elevated Expression of IL-12 p40 Observed after Challenge with Helicobacter hepaticus
Tomczak, Michal F., Gadjeva, Mihaela, Wang, Yan Yan, Brown, Ketorah, Maroulakou, Ioanna, Tsichlis, Philip N., Erdman, Susan E., Fox, James G., Horwitz, Bruce H.
Published in Journal of Immunology (15.01.2006)
Published in Journal of Immunology (15.01.2006)
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Journal Article
Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival
DE VITA, G, MELILLO, R. M, CARLOMAGNO, F, VISCONTI, R, CASTELLONE, M. D, BELLACOSA, A, BILLAUD, M, FUSCO, A, TSICHLIS, P. N, SANTORO, M
Published in Cancer research (Chicago, Ill.) (15.07.2000)
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Published in Cancer research (Chicago, Ill.) (15.07.2000)
Journal Article
The Oncogenic Protein Kinase Tpl-2/Cot Contributes to Epstein-Barr Virus-Encoded Latent Infection Membrane Protein 1-Induced NF-κB Signaling Downstream of TRAF2
Eliopoulos, Aristides G., Davies, Clare, Blake, Sarah S. M., Murray, Paul, Najafipour, Sohrab, Tsichlis, Philip N., Young, Lawrence S.
Published in Journal of Virology (01.05.2002)
Published in Journal of Virology (01.05.2002)
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Journal Article
Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment
Doan, Loretta L, Kitay, Mary Kate, Yu, Qing, Singer, Alfred, Herblot, Sabine, Hoang, Trang, Bear, Susan E, Morse, 3rd, Herbert C, Tsichlis, Philip N, Grimes, H Leighton
Published in The Journal of immunology (1950) (01.03.2003)
Published in The Journal of immunology (1950) (01.03.2003)
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Journal Article
Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4
Chavdoula, Evangelia, Anastas, Vollter, Ferlita, Alessandro La, Aldana, Julian, Carota, Giuseppe, Spampinato, Mariarita, Soysal, Burak, Cosentini, Ilaria, Parashar, Sameer, Sircar, Anuvrat, Nigita, Giovanni, Sehgal, Lalit, Freitas, Michael A, Tsichlis, Philip N
Published in bioRxiv (11.07.2023)
Published in bioRxiv (11.07.2023)
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Journal Article
Differential Roles of Akt, Rac, and Ral in R-Ras-Mediated Cellular Transformation, Adhesion, and Survival
Osada, Masako, Tolkacheva, Tatyana, Li, Weiqun, Chan, Tung O., Tsichlis, Philip N., Saez, Rosana, Kimmelman, Alec C., Chan, Andrew M.-L.
Published in Molecular and Cellular Biology (01.09.1999)
Published in Molecular and Cellular Biology (01.09.1999)
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Journal Article
Tumor Progression Locus 2 (Tpl-2) Encodes a Protein Kinase Involved in the Progression of Rodent T-Cell Lymphomas and in T-Cell Activation
Patriotis, Christos, Makris, Antonios, Bear, Susan E., Tsichlis, Philip N.
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (15.03.1993)
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