BEECH: a dose-finding run-in followed by a randomised phase II study assessing the efficacy of AKT inhibitor capivasertib (AZD5363) combined with paclitaxel in patients with estrogen receptor-positive advanced or metastatic breast cancer, and in a PIK3CA mutant sub-population
Turner, N.C., Alarcón, E., Armstrong, A.C., Philco, M., López Chuken, Y.A., Sablin, M.-P., Tamura, K., Gómez Villanueva, A., Pérez-Fidalgo, J.A., Cheung, S.Y.A., Corcoran, C., Cullberg, M., Davies, B.R., de Bruin, E.C., Foxley, A., Lindemann, J.P.O., Maudsley, R., Moschetta, M., Outhwaite, E., Pass, M., Rugman, P., Schiavon, G., Oliveira, M.
Published in Annals of oncology (01.05.2019)
Published in Annals of oncology (01.05.2019)
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Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: a randomised phase III noninferiority trial
Kang, Y.-K., Kang, W.-K., Shin, D.-B., Chen, J., Xiong, J., Wang, J., Lichinitser, M., Guan, Z., Khasanov, R., Zheng, L., Philco-Salas, M., Suarez, T., Santamaria, J., Forster, G., McCloud, P. I.
Published in Annals of oncology (01.04.2009)
Published in Annals of oncology (01.04.2009)
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3501 ORAL Capecitabine/cisplatin vs. continuous infusion of 5-FU/cisplatin as first-line therapy in patients (pts) with advanced gastric cancer (AGC): a randomised phase III trial
Kang, Y, Kang, W, Shin, D, Chen, J, Xiong, J, Wang, J, Lichinitser, M, Philco, M, Suarez, T, Santamaría, J
Published in European journal of cancer supplements (2007)
Published in European journal of cancer supplements (2007)
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BEECH: A randomised Phase 2 study assessing the efficacy of AKT inhibitor AZD5363 combined with paclitaxel in patients with ER+ve advanced or metastatic breast cancer, and in a PIK3CA mutant sub-population
Turner, N., Alarcón, E., Armstrong, A., Philco, M., López Chuken, Y.A., Sablin, M-P., Tamura, K., Gomez Villanueva, A., Pérez-Fidalgo, J.A., Foxley, A., Lindemann, J., Maudsley, R., Outhwaite, E., Pass, M., Rugman, P., Schiavon, G., Oliveira, M.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
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11 Flabra, frontline approach for BRCA testing in ovarian cancer (OC) treatment naïve population. A latin america (LA) epidemiologic study
Goncalves, S, Gomez Abuin, G, Gallardo, D, Estevez Diz, P, Caceres, V, De la Vega, M, Palazzo, F, Lerzo, G, Kaen, D, Gerson, R, Lim, M, Philco, M, Moreira Costa Zorzzeto, M, De Melo, AC, Hegg, R, de Oliveira Santana, R, Medeiros Milhomen Beato, P, Trujillo, L, Plata, M, Yepes, A, Cock, A, Bonifacino, MM, Cortes, M, Fein, L, Castillo, C, Pacheco, C, Ticona, M, Hoyoa, E, Jaramillo, R, Soare Nunes, J, Menezes Morelle, A, Freire de Carvalho Calabrich, A, Cronemberger Costa e Silva, EH, Mora, P, Damian, F, Diaz Perez, I, Sganga, L, Pereira, MH, Ramirez, H, Nogueira, A, Guindalini, R, Miranda, V, Giornelli, G
Published in International journal of gynecological cancer (01.09.2019)
Published in International journal of gynecological cancer (01.09.2019)
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Phase I dose-escalation and pharmacokinetic study of ispinesib, a kinesin spindle protein inhibitor, administered on days 1 and 15 of a 28-day schedule in patients with no prior treatment for advanced breast cancer
Gomez, Henry L, Philco, Manuel, Pimentel, Patricia, Kiyan, Miriam, Monsalvo, Maria Laura, Conlan, Maureen G, Saikali, Khalil G, Chen, Michael M, Seroogy, Joseph J, Wolff, Andrew A, Escandon, Rafael D
Published in Anti-cancer drugs (01.03.2012)
Published in Anti-cancer drugs (01.03.2012)
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A Phase I-II Trial of Ispinesib, a Kinesin Spindle Protein Inhibitor, Dosed Every Two Weeks as First Line Chemotherapy for Advanced Locally Recurrent or Metastatic Breast Cancer
Gomez, H., Philco, M., Pimentel, P., Escandon, R., Saikali, K., Seroogy, J., Wolff, A., Conlan, M.
Published in Cancer research (Chicago, Ill.) (15.12.2009)
Published in Cancer research (Chicago, Ill.) (15.12.2009)
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BEECH: a dose-finding run-in followed by a randomised phase II study assessing the efficacy of AKT inhibitor capivasertib (AZD5363) combined with paclitaxel in patients with estrogen receptor-positive advanced or metastatic breast cancer, and in a PIK3CA mutant sub-population
Turner, N C, Alarcón, E, Armstrong, A C, Philco, M, López Chuken, Y A, Sablin, M-P, Tamura, K, Gómez Villanueva, A, Pérez-Fidalgo, J A, Cheung, S Y A, Corcoran, C, Cullberg, M, Davies, B R, de Bruin, E C, Foxley, A, Lindemann, J P O, Maudsley, R, Moschetta, M, Outhwaite, E, Pass, M, Rugman, P, Schiavon, G, Oliveira, M
Published in Annals of oncology (01.05.2019)
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Published in Annals of oncology (01.05.2019)
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A phase I/II trial of ispinesib, a kinesin spindle protein (KSP) inhibitor, dosed q14d in patients with advanced breast cancer previously untreated with chemotherapy for metastatic disease or recurrence
Gomez, H. L., Philco, M., Castaneda, C., Pimentel, P., Escandon, R., Seroogy, J., Saikali, K., Wolff, A., Conlan, M.
Published in Journal of clinical oncology (20.05.2009)
Published in Journal of clinical oncology (20.05.2009)
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A phase I-II open-label trial of ispinesib on an alternate dosing schedule in chemotherapy-naive patients with locally advanced or metastatic breast cancer (MBC)
Philco, M., Falcon, S., Gomez, H., Escandon, R., Saikali, K., Wolff, A.
Published in Journal of clinical oncology (20.05.2008)
Published in Journal of clinical oncology (20.05.2008)
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A phase I-II trial of Ispinesib , a kinesin spindle protein inhibitor, dosed every two weeks in patients with locally advanced or metastatic breast cancer previously untreated with chemotherapy for metastatic disease or recurrence
Gomez, H, Castaneda, C, Philco, M, Pimentel, P, Falcon, S, Escandon, R, Saikali, K, Conlan, M, Seroogy, J, Wolff, A
Published in Cancer research (Chicago, Ill.) (15.01.2009)
Published in Cancer research (Chicago, Ill.) (15.01.2009)
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Randomized phase III trial of capecitabine/cisplatin (XP) vs. continuous infusion of 5-FU/cisplatin (FP) as first-line therapy in patients (pts) with advanced gastric cancer (AGC): Efficacy and safety results
Kang, Y., Kang, W. K., Shin, D. B., Chen, J., Xiong, J., Wang, J., Lichinitser, M., Philco, M., Suarez, T., Santamaria, J.
Published in Journal of clinical oncology (20.06.2006)
Published in Journal of clinical oncology (20.06.2006)
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FALCON: A phase III randomised trial of fulvestrant 500 mg vs. anastrozole for hormone receptor-positive advanced breast cancer
Ellis, M.J., Bondarenko, I., Trishkina, E., Dvorkin, M., Panasci, L., Manikhas, A., Shparyk, Y., Cardona-Huerta, S., Cheung, K.-L., Philco-Salas, M.J., Ruiz-Borrego, M., Shao, Z., Noguchi, S., Grinsted, L.M., Fazal, M., Stuart, M., Robertson, J.F.
Published in Annals of oncology (01.10.2016)
Published in Annals of oncology (01.10.2016)
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