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A double-blind study of MPV-2213ad, a novel aromatase inhibitor, in healthy male subjects
Ahokoski, O., Irjala, K., Huhtala, S., Salminen, E., Scheinin, H., Huupponen, R.
Published in European journal of clinical pharmacology (17.03.1999)
Published in European journal of clinical pharmacology (17.03.1999)
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570P A first-in-human phase I study of the AXL inhibitor DS-1205c in combination with gefitinib in subjects with EGFR-mutant NSCLC
R. Toyozawa, Isamu Okamoto, G. Takayama, M. Ishigami, M. Uno, K. Goto, Makoto Nishio, E. Slosberg, Masayuki Takeda, Haruyasu Murakami, N. Crawford, T. Jimbo, H. Horinouchi, S. Nakayama, S. Ohwada
Published in Annals of Oncology (01.09.2020)
Published in Annals of Oncology (01.09.2020)
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Phase I study of the AXL inhibitor DS-1205c in combination with osimertinib in subjects with metastatic or unresectable EGFR-mutant NSCLC
T. Goldberg, David Planchard, J. McGill, Pasi A. Jänne, X. Gu, Helena Alexandra Yu, Denis Moro-Sibilot, J. Li, C. Yu, E. Slosberg
Published in Annals of Oncology (01.10.2018)
Published in Annals of Oncology (01.10.2018)
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A Phase I Study Comparing the Pharmacokinetics, Safety, and Immunogenicity of A140 Injection and Cetuximab (Erbitux®) in Healthy Chinese Male Subjects
Xu, Jia, Ge, Junyou, Li, Yaling, Liu, Shulin, Li, Sicong, Si, Jing, Liu, Juncheng, Zhu, Xiaoxue, Ding, Yanhua
Published in Advances in therapy (01.06.2025)
Published in Advances in therapy (01.06.2025)
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[68Ga]Ga-interleukin-2 for imaging activated T-lymphocytes: biochemical characterization and phase I study in normal subjects
Signore, Alberto, Galli, Filippo, Varani, Michela, Campagna, Giuseppe, Bentivoglio, Valeria, Accardo, Antonella, Morelli, Giancarlo, Lauri, Chiara
Published in European journal of nuclear medicine and molecular imaging (01.07.2025)
Published in European journal of nuclear medicine and molecular imaging (01.07.2025)
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Phase I study of [68Ga]Ga-HX01 for targeting integrin αvβ3 and CD13 in healthy and malignancy subjects
Zhang, Xiao, Fang, Hanyi, Yang, Biao, Qin, Chunxia, Hu, Fan, Ruan, Weiwei, Chen, Jing, Zeng, Dexing, Gai, Yongkang, Lan, Xiaoli
Published in European journal of nuclear medicine and molecular imaging (01.03.2025)
Published in European journal of nuclear medicine and molecular imaging (01.03.2025)
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First-in-human phase I study of ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), in subjects with open-angle glaucoma undergoing glaucoma filtration surgery
Pfeiffer, Norbert, Voykov, Bogomil, Renieri, Giulia, Bell, Katharina, Richter, Paul, Weigel, Melanie, Thieme, Hagen, Wilhelm, Barbara, Lorenz, Katrin, Feindor, Martin, Wosikowski, Katja, Janicot, Michel, Päckert, Daniela, Römmich, Regina, Mala, Carola, Fettes, Petra, Leo, Eugen
Published in PloS one (30.11.2017)
Published in PloS one (30.11.2017)
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Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti–IL-5 receptor α antibody, in a phase I study of subjects with mild asthma
Busse, William W., Katial, Rohit, Gossage, David, Sari, Suha, Wang, Bing, Kolbeck, Roland, Coyle, Anthony J., Koike, Masamichi, Spitalny, George L., Kiener, Peter A., Geba, Gregory P., Molfino, Nestor A.
Published in Journal of allergy and clinical immunology (01.06.2010)
Published in Journal of allergy and clinical immunology (01.06.2010)
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EDP‐297: A novel, farnesoid X receptor agonist—Results of a phase I study in healthy subjects
Marotta, Christine, Ahmad, Alaa, Luo, Ed, Oosterhaven, Jart, Marle, Sjoerd, Adda, Nathalie
Published in Clinical and translational science (01.02.2023)
Published in Clinical and translational science (01.02.2023)
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P2.06-002 Phase I Study of DS-6051b, a ROS1/NTRK Inhibitor, in Japanese Subjects with Advanced Solid Tumors Harboring Either a ROS1 or NTRK Fusion Gene
Kenji Nakamaru, Masayuki Takeda, Kaname Nosaki, Ryota Shiga, Yutaka Fujiwara, Chihiro Abe, Kazuhiko Nakagawa, Takashi Seto, Noboru Yamamoto
Published in Journal of Thoracic Oncology (01.01.2017)
Published in Journal of Thoracic Oncology (01.01.2017)
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Safety, pharmacokinetics, and pharmacodynamics of ART‐648, a PDE4 inhibitor in healthy subjects: A randomized, placebo‐controlled phase I study
Tanaka, Akira, Nagabukuro, Hiroshi, Kuniyeda, Kanako, Ando, Haruhi, Higashi, Toshinori, Wakuda, Hirokazu, Otani, Naoyuki, Kudo, Hideo, Kuranari, Masae, Furuie, Hidetoshi, Uemura, Naoto
Published in Clinical and translational science (01.10.2024)
Published in Clinical and translational science (01.10.2024)
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Phase I study of BAY 94‐9027, a PEGylated B‐domain‐deleted recombinant factor VIII with an extended half‐life, in subjects with hemophilia A
Coyle, T. E., Reding, M. T., Lin, J. C., Michaels, L. A., Shah, A., Powell, J.
Published in Journal of thrombosis and haemostasis (01.04.2014)
Published in Journal of thrombosis and haemostasis (01.04.2014)
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Safety, pharmacokinetics, and pharmacodynamics of anti‐IL‐4Rα antibody SHR‐1819 in healthy subjects: A randomized, controlled phase I study
Li, Na, Shakib, Sepehr, Qian, Weilin, Yao, Xiaoyan, Li, Puyuan, Nip, Tsz Keung, Bai, Xiaoyan, Shen, Kai
Published in Clinical and translational science (01.04.2024)
Published in Clinical and translational science (01.04.2024)
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A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours
Dredge, Keith, Brennan, Todd V., Hammond, Edward, Lickliter, Jason D., Lin, Liwen, Bampton, Darryn, Handley, Paul, Lankesheer, Fleur, Morrish, Glynn, Yang, Yiping, Brown, Michael P., Millward, Michael
Published in British journal of cancer (01.04.2018)
Published in British journal of cancer (01.04.2018)
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Erratum for Yang et al., “A phase I study of the safety, tolerability, and pharmacokinetics of contezolid acefosamil after intravenous and oral administration in healthy Chinese subjects”
Yang, Haijing, Jin, Yi, Wang, Hailin, Yuan, Hong, Wang, Jingjing, Li, Size, Hu, Yingying, Yang, Huahui, Li, Xin, Liang, Hong, Wu, Jufang, Cao, Guoying, Zhang, Jing
Published in Antimicrobial agents and chemotherapy (08.10.2024)
Published in Antimicrobial agents and chemotherapy (08.10.2024)
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68GaGa-interleukin-2 for imaging activated T-lymphocytes: biochemical characterization and phase I study in normal subjects
Signore, Alberto, Galli, Filippo, Varani, Michela, Campagna, Giuseppe, Bentivoglio, Valeria, Accardo, Antonella, Morelli, Giancarlo, Lauri, Chiara
Published in European journal of nuclear medicine and molecular imaging (01.07.2025)
Published in European journal of nuclear medicine and molecular imaging (01.07.2025)
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Complete Removal of Extracellular IgG Antibodies in a Randomized Dose-Escalation Phase I Study with the Bacterial Enzyme IdeS – A Novel Therapeutic Opportunity
Winstedt, Lena, Järnum, Sofia, Nordahl, Emma Andersson, Olsson, Andreas, Runström, Anna, Bockermann, Robert, Karlsson, Christofer, Malmström, Johan, Palmgren, Gabriella Samuelsson, Malmqvist, Ulf, Björck, Lars, Kjellman, Christian
Published in PloS one (2015)
Published in PloS one (2015)
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Results from phase I study of the oncolytic viral immunotherapy agent canerpaturev (C-REV) in combination with gemcitabine plus nab-paclitaxel for unresectable pancreatic cancer
Yusuke Hashimoto, Makoto Ueno, Masafumi Ikeda, Maki Tanaka
Published in Journal of Clinical Oncology (01.02.2019)
Published in Journal of Clinical Oncology (01.02.2019)
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Pharmacokinetic equivalence of CT‐P17 to high‐concentration (100 mg/ml) reference adalimumab: A randomized phase I study in healthy subjects
Yu, Kyung‐Sang, Jang, In‐Jin, Lim, Hyeong‐Seok, Hong, Jang Hee, Kim, Min‐Gul, Park, Min Kyu, Cho, Doo‐Yeoun, Park, Min Soo, Chung, Jae Yong, Ghim, Jong‐Lyul, Lee, SeungHwan, Yoon, Seok Kyu, Kwon, In Sun, Lee, Sang Joon, Kim, Sung Hyun, Bae, Yun Ju, Cha, Jung Bin, Furst, Daniel E., Keystone, Edward, Kay, Jonathan
Published in Clinical and translational science (01.07.2021)
Published in Clinical and translational science (01.07.2021)
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