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A phase I study investigation of metabolism, and disposition of [14C]-anlotinib after an oral administration in patients with advanced refractory solid tumors
Liu, Yiqian, Liu, Lianke, Liu, Lingxiang, Wang, Tongshan, Guo, Lian, Wang, Yixiang, Gao, Zhengzhen, Shu, Yongqian
Published in Cancer chemotherapy and pharmacology (01.05.2020)
Published in Cancer chemotherapy and pharmacology (01.05.2020)
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Allogeneic adipose tissue‐derived stem cells ELIXCYTE® in chronic kidney disease: A phase I study assessing safety and clinical feasibility
Zheng, Cai‐Mei, Chiu, I‐Jen, Chen, Yu‐Wei, Hsu, Yung‐Ho, Hung, Lie‐Yee, Wu, Mei‐Yi, Lin, Yuh‐Feng, Liao, Chia‐Te, Hung, Yi‐Pei, Tsai, Chia‐Chu, Cherng, Yih‐Giun, Wu, Mai‐Szu
Published in Journal of cellular and molecular medicine (01.05.2022)
Published in Journal of cellular and molecular medicine (01.05.2022)
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Antigen-Specific Immunotherapy with Thyrotropin Receptor Peptides in Graves' Hyperthyroidism: A Phase I Study
Pearce, Simon H.S., Dayan, Colin, Wraith, David C., Barrell, Kevin, Olive, Natalie, Jansson, Lotta, Walker-Smith, Terrie, Carnegie, Christina, Martin, Keith F., Boelaert, Kristien, Gilbert, Jackie, Higham, Claire E., Muller, Ilaria, Murray, Robert D., Perros, Petros, Razvi, Salman, Vaidya, Bijay, Wernig, Florian, Kahaly, George J.
Published in Thyroid (New York, N.Y.) (01.07.2019)
Published in Thyroid (New York, N.Y.) (01.07.2019)
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A phase I study to evaluate the safety, tolerability, and pharmacokinetics of HEC113995PA·H2O, a novel dual-acting serotonergic antidepressant, in healthy subjects
Wu, Xue, Wu, Qingqing, Ding, Qichen, Zhuang, Yulei, Luo, Lin, Zhang, Yingjun, Deng, Li, Jin, Chuanfei, Li, Xue, Huang, Zhangma, Qin, Haiping, Xin, Liang, Chen, Qian, Jia, Jingying, Liu, Yanmei
Published in Frontiers in pharmacology (26.03.2025)
Published in Frontiers in pharmacology (26.03.2025)
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Phase I study of liver depot gene therapy in late-onset Pompe disease
Smith, Edward C., Hopkins, Sam, Case, Laura E., Xu, Ming, Walters, Crista, Dearmey, Stephanie, Han, Sang-oh, Spears, Tracy G., Chichester, Jessica A., Bossen, Edward H., Hornik, Christoph P., Cohen, Jennifer L., Bali, Deeksha, Kishnani, Priya S., Koeberl, Dwight D.
Published in Molecular therapy (05.07.2023)
Published in Molecular therapy (05.07.2023)
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Safety and efficacy of BAY1436032 in IDH1-mutant AML: phase I study results
Heuser, Michael, Palmisiano, Neil, Mantzaris, Ioannis, Mims, Alice, DiNardo, Courtney, Silverman, Lewis R., Wang, Eunice S., Fiedler, Walter, Baldus, Claudia, Schwind, Sebastian, Pardee, Timothy, Perl, Alexander E., Cai, Charles, Kaulfuss, Stefan, Lagkadinou, Eleni, Rentzsch, Christine, Wagner, Markus, Wilkinson, Gary, Wu, Bingyan, Jeffers, Michael, Genvresse, Isabelle, Krämer, Alwin
Published in Leukemia (01.11.2020)
Published in Leukemia (01.11.2020)
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An innovative phase I study in healthy subjects to determine the mass balance, elimination, metabolism, and absolute bioavailability of mitapivat
Prakash, Chandra, Mangus, Heidi, Yan, Yan, Yang, Hua, Iyer, Varsha
Published in Clinical and translational science (01.10.2023)
Published in Clinical and translational science (01.10.2023)
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A phase I study to evaluate the safety, tolerability, and pharmacokinetics of HEC113995PA·H 2 O, a novel dual-acting serotonergic antidepressant, in healthy subjects
Wu, Xue, Wu, Qingqing, Ding, Qichen, Zhuang, Yulei, Luo, Lin, Zhang, Yingjun, Deng, Li, Jin, Chuanfei, Li, Xue, Huang, Zhangma, Qin, Haiping, Xin, Liang, Chen, Qian, Jia, Jingying, Liu, Yanmei
Published in Frontiers in pharmacology (2025)
Published in Frontiers in pharmacology (2025)
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A phase I study of the novel immunotoxin, MT-5111, in subjects (subj) with HER-2 positive tumors: Interim results
Wainberg, Zev A., Barve, Minal A., Hamilton, Erika Paige, Brenner, Andrew Jacob, Valdes, Frances, Mita, Monica M., González, Valeria, Anand, Banmeet S., Burnett, Christine, Pelham, Joshua, Waltzman, Roger J., Strack, Thomas, Van Tine, Brian A.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Abstract 27: A phase I study of MEK inhibitor BAY 86-9766 in Japanese patients with advanced or reflactory solid tumors
Katsuya Tsukada, Susumu Koyama, Takayuki Yoshino, Hideaki Bando, Kohei Shitara, Hideaki Miyamoto, Toshihiko Doi, Atsushi Ohtsu, Nozomi Fuse
Published in Cancer Research (01.04.2013)
Published in Cancer Research (01.04.2013)
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A Phase I Study to Evaluate the Relative Bioavailability, Pharmacodynamics, and Safety of a Single Subcutaneous Injection of Recaticimab at Three Different Sites in Healthy Chinese Subjects
Wang, Ying, Cheng, Yuanzhi, Guo, Yuhan, Fan, Yang, Zhou, Renpeng, Zhang, Qian, Xu, Ye, Feng, Sheng, Shen, Kai, Hu, Wei
Published in European journal of drug metabolism and pharmacokinetics (01.05.2025)
Published in European journal of drug metabolism and pharmacokinetics (01.05.2025)
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A phase I study to evaluate the safety, tolerability, and pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy Chinese subjects
Chen, Qian, Wu, Qingqing, Song, Rong, Wang, Yating, Zhang, Mengqi, Li, Fangqiong, Zeng, Weifang, Wang, Wei, Jia, Jingying, Yu, Chen, Liu, Yanmei
Published in Frontiers in pharmacology (11.12.2023)
Published in Frontiers in pharmacology (11.12.2023)
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Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects
Hutchins, Laura F., Makhoul, Issam, Emanuel, Peter D., Pennisi, Angela, Siegel, Eric R., Jousheghany, Fariba, Guo, Xueyan, Pashov, Anastas D., Monzavi-Karbassi, Behjatolah, Kieber-Emmons, Thomas
Published in Oncotarget (17.11.2017)
Published in Oncotarget (17.11.2017)
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Safety and long-term immunological effects of CryJ2-LAMP plasmid vaccine in Japanese red cedar atopic subjects: A phase I study
Su, Yan, Romeu-Bonilla, Eliezer, Anagnostou, Athanasia, Fitz-Patrick, David, Hearl, William, Heiland, Teri
Published in Human vaccines & immunotherapeutics (02.12.2017)
Published in Human vaccines & immunotherapeutics (02.12.2017)
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A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects
Liu, Yun, Yu, Chengyin, Zhang, Yifan, Xie, Zhifu, Wang, Yating, Qian, Hongjie, Liang, Liyu, Liu, Yanmei, Chen, Qian, Jia, Jingying, Yan, Sai, Lai, Xiaoyin, Li, Wei, Li, Jingya, Zhang, Yangming, Nan, Fajun, Yu, Chen
Published in Drug design, development and therapy (01.01.2025)
Published in Drug design, development and therapy (01.01.2025)
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Phase I study to evaluate of the gastric pH-dependent drug interaction between famitinib and the proton pump inhibitor omeprazole in healthy subjects
Hu, Linlin, Cai, Mingmin, Qian, Wei, Dou, Ting, Sun, Qiuyue, Tang, Lu, Wang, Huiping
Published in Investigational new drugs (01.12.2022)
Published in Investigational new drugs (01.12.2022)
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First-in-human safety, tolerability, and pharmacokinetics of ammoxetine in healthy subjects: a randomized, double-blind, placebo-controlled phase I study
Shen, Qi, Hu, Chao, Miao, Jia, Chen, Junxia, Peng, Yueying, Pan, Tingting, He, Xiaolin, Yuan, Jing, Ni, Shaonan, Wang, Yongsheng, Luo, Zhu
Published in European journal of pharmaceutical sciences (01.04.2021)
Published in European journal of pharmaceutical sciences (01.04.2021)
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S1057 A Randomized Phase I Study Comparing Pharmacokinetics, Safety and Immunogenicity of High Concentration Formulation (100 mg/mL) With GP2017 Formulation (50 mg/mL), an Adalimumab Biosimilar, in Healthy Male Subjects
Rondon, Juan Carlos, Von Richter, Oliver, Fey, Constanze, Fan, Jamie, Furlan, Fabricio, Lemke, Lena
Published in The American journal of gastroenterology (01.10.2022)
Published in The American journal of gastroenterology (01.10.2022)
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First clinical and immunogenicity results including all subjects enrolled in a phase I study of Nous-209, an off-the-shelf immunotherapy, with pembrolizumab, for the treatment of tumors with a deficiency in mismatch repair/microsatellite instability (dMMR/MSI)
Fakih, Marwan, Le, Dung T., Pedersen, Katrina Sophia, Shields, Anthony Frank, Shah, Manish A., Mukherjee, Sarbajit, Delaite, Patricia, Faivre, Théa, D'Alise, Anna Morena, Leoni, Guido, Cotugno, Gabriella, Langone, Francesca, Scarselli, Elisa, Overman, Michael J.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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A phase I study comparing the pharmacokinetics of the biosimilar in healthy Chinese male subjects
Zhou, Ruirui, Guo, Linfeng, Gao, Xianglei, Wang, Yijun, Xu, Wenjing, Zou, Yang, Li, Wenjia, Zhuang, Yulei, Liu, Gangyi, Liu, Yanmei
Published in Clinical and translational science (01.10.2022)
Published in Clinical and translational science (01.10.2022)
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