High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)
Niemi, Mikko, Schaeffeler, Elke, Lang, Thomas, Fromm, Martin F, Neuvonen, Mikko, Kyrklund, Carl, Backman, Janne T, Kerb, Reinhold, Schwab, Matthias, Neuvonen, Pertti J, Eichelbaum, Michel, Kivistö, Kari T
Published in Pharmacogenetics (London) (01.07.2004)
Published in Pharmacogenetics (London) (01.07.2004)
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Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants
Schaeffeler, Elke, Fischer, Christine, Brockmeier, Dierk, Wernet, Dorothee, Moerike, Klaus, Eichelbaum, Michel, Zanger, Ulrich M, Schwab, Matthias
Published in Pharmacogenetics (London) (01.07.2004)
Published in Pharmacogenetics (London) (01.07.2004)
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A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels
Mandola, Michael V, Stoehlmacher, Jan, Zhang, Wu, Groshen, Susan, Yu, Mimi C, Iqbal, Syma, Lenz, Heinz-Josef, Ladner, Robert D
Published in Pharmacogenetics (London) (01.05.2004)
Published in Pharmacogenetics (London) (01.05.2004)
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Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene
Kroetz, Deanna L, Pauli-Magnus, Christiane, Hodges, Laura M, Huang, Conrad C, Kawamoto, Michiko, Johns, Susan J, Stryke, Doug, Ferrin, Thomas E, DeYoung, Joseph, Taylor, Travis, Carlson, Elaine J, Herskowitz, Ira, Giacomini, Kathleen M, Clark, Andrew G
Published in Pharmacogenetics (London) (01.08.2003)
Published in Pharmacogenetics (London) (01.08.2003)
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Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants
Nelson, David R, Zeldin, Darryl C, Hoffman, Susan M G, Maltais, Lois J, Wain, Hester M, Nebert, Daniel W
Published in Pharmacogenetics (London) (01.01.2004)
Published in Pharmacogenetics (London) (01.01.2004)
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Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase)
Marinaki, Anthony M, Ansari, Azhar, Duley, John A, Arenas, Monica, Sumi, Satoshi, Lewis, Cathryn M, Shobowale-Bakre, El-Monsor, Escuredo, Emilia, Fairbanks, Lynette D, Sanderson, Jeremy D
Published in Pharmacogenetics (London) (01.03.2004)
Published in Pharmacogenetics (London) (01.03.2004)
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Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver
Lang, T, Klein, K, Fischer, J, Nüssler, A K, Neuhaus, P, Hofmann, U, Eichelbaum, M, Schwab, M, Zanger, U M
Published in Pharmacogenetics (London) (01.07.2001)
Published in Pharmacogenetics (London) (01.07.2001)
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Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy
Pauli-Magnus, Christiane, Lang, Thomas, Meier, Yvonne, Zodan-Marin, Tina, Jung, Diana, Breymann, Christian, Zimmermann, Roland, Kenngott, Silke, Beuers, Ulrich, Reichel, Christoph, Kerb, Reinhold, Penger, Anja, Meier, Peter J, Kullak-Ublick, Gerd A
Published in Pharmacogenetics (London) (01.02.2004)
Published in Pharmacogenetics (London) (01.02.2004)
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Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans
Vogelgesang, Silke, Cascorbi, Ingolf, Schroeder, Eike, Pahnke, Jens, Kroemer, Heyo K, Siegmund, Werner, Kunert-Keil, Christiane, Walker, Lary C, Warzok, Rolf W
Published in Pharmacogenetics (London) (01.10.2002)
Published in Pharmacogenetics (London) (01.10.2002)
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Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver
Girard, Hugo, Court, Michael H, Bernard, Olivier, Fortier, Louis-Charles, Villeneuve, Lyne, Hao, Qin, Greenblatt, David J, von Moltke, Lisa L, Perussed, Louis, Guillemette, Chantal
Published in Pharmacogenetics (London) (01.08.2004)
Published in Pharmacogenetics (London) (01.08.2004)
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Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine
Zamber, Charis P, Lamba, Jatinder K, Yasuda, Kazuto, Farnum, Jennifer, Thummel, Kenneth, Schuetz, John D, Schuetz, Erin G
Published in Pharmacogenetics (London) (01.01.2003)
Published in Pharmacogenetics (London) (01.01.2003)
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Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene
Mealey, K L, Bentjen, S A, Gay, J M, Cantor, G H
Published in Pharmacogenetics (London) (01.11.2001)
Published in Pharmacogenetics (London) (01.11.2001)
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Common allelic variants of cytochrome P4503A4 and their prevalence in different populations
Lamba, Jatinder K, Lin, Yvonne S, Thummel, Kenneth, Daly, Ann, Watkins, Paul B, Strom, Stephen, Zhang, Jiong, Schuetz, Erin G
Published in Pharmacogenetics (London) (01.03.2002)
Published in Pharmacogenetics (London) (01.03.2002)
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Contribution of common polymorphisms in reduced folate carrier and gamma-glutamylhydrolase to methotrexate polyglutamate levels in patients with rheumatoid arthritis
Dervieux, Thierry, Kremer, Joel, Lein, Diana Orentas, Capps, Robert, Barham, Robert, Meyer, Gary, Smith, Katie, Caldwell, Jacques, Furst, Daniel E
Published in Pharmacogenetics (London) (01.11.2004)
Published in Pharmacogenetics (London) (01.11.2004)
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The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
Hitzl, M, Drescher, S, van der Kuip, H, Schäffeler, E, Fischer, J, Schwab, M, Eichelbaum, M, Fromm, M F
Published in Pharmacogenetics (London) (01.06.2001)
Published in Pharmacogenetics (London) (01.06.2001)
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The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients
Haufroid, Vincent, Mourad, Michel, Van Kerckhove, Valérie, Wawrzyniak, Jeremie, De Meyer, Martine, Eddour, Djamila Chaib, Malaise, Jacques, Lison, Dominique, Squifflet, Jean-Paul, Wallemacq, Pierre
Published in Pharmacogenetics (London) (01.03.2004)
Published in Pharmacogenetics (London) (01.03.2004)
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Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses
Urano, Wako, Taniguchi, Atsuo, Yamanaka, Hisashi, Tanaka, Eiichi, Nakajima, Hiroshi, Matsuda, Yuko, Akama, Hideto, Kitamura, Yutaka, Kamatani, Naoyuki
Published in Pharmacogenetics (London) (01.04.2002)
Published in Pharmacogenetics (London) (01.04.2002)
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