Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells
Karamitros, Dimitris, Stoilova, Bilyana, Aboukhalil, Zahra, Hamey, Fiona, Reinisch, Andreas, Samitsch, Marina, Quek, Lynn, Otto, Georg, Repapi, Emmanouela, Doondeea, Jessica, Usukhbayar, Batchimeg, Calvo, Julien, Taylor, Stephen, Goardon, Nicolas, Six, Emmanuelle, Pflumio, Francoise, Porcher, Catherine, Majeti, Ravindra, Göttgens, Berthold, Vyas, Paresh
Published in Nature immunology (01.01.2018)
Published in Nature immunology (01.01.2018)
Get full text
Journal Article
Developmental interplay between transcriptional alterations and a targetable cytokine signaling dependency in pediatric ETO2::GLIS2 leukemia
Alonso-Pérez, Verónica, Galant, Klaudia, Boudia, Fabien, Robert, Elie, Aid, Zakia, Renou, Laurent, Barroca, Vilma, Devanand, Saryiami, Babin, Loélia, Rouiller-Fabre, Virginie, Moison, Delphine, Busso, Didier, Piton, Guillaume, Metereau, Christophe, Abermil, Nassera, Ballerini, Paola, Hirsch, Pierre, Haddad, Rima, Martinovic, Jelena, Petit, Arnaud, Lapillonne, Hélène, Brunet, Erika, Mercher, Thomas, Pflumio, Françoise
Published in Molecular cancer (20.09.2024)
Published in Molecular cancer (20.09.2024)
Get full text
Journal Article
Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL
Passet, Marie, Kim, Rathana, Gachet, Stéphanie, Sigaux, François, Chaumeil, Julie, Galland, Ava, Sexton, Thomas, Quentin, Samuel, Hernandez, Lucie, Larcher, Lise, Bergugnat, Hugo, Ye, Tao, Karasu, Nezih, Caye, Aurélie, Heizmann, Beate, Duluc, Isabelle, Chevallier, Patrice, Rousselot, Philippe, Huguet, Françoise, Leguay, Thibaut, Hunault, Mathilde, Pflumio, Françoise, Freund, Jean-Noël, Lobry, Camille, Lhéritier, Véronique, Dombret, Hervé, Domon-Dell, Claire, Soulier, Jean, Boissel, Nicolas, Clappier, Emmanuelle
Published in Blood (16.06.2022)
Published in Blood (16.06.2022)
Get full text
Journal Article
ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia
Thirant, Cécile, Ignacimouttou, Cathy, Lopez, Cécile K., Diop, M’Boyba, Le Mouël, Lou, Thiollier, Clarisse, Siret, Aurélie, Dessen, Phillipe, Aid, Zakia, Rivière, Julie, Rameau, Philippe, Lefebvre, Céline, Khaled, Mehdi, Leverger, Guy, Ballerini, Paola, Petit, Arnaud, Raslova, Hana, Carmichael, Catherine L., Kile, Benjamin T., Soler, Eric, Crispino, John D., Wichmann, Christian, Pflumio, Françoise, Schwaller, Jürg, Vainchenker, William, Lobry, Camille, Droin, Nathalie, Bernard, Olivier A., Malinge, Sébastien, Mercher, Thomas
Published in Cancer cell (13.03.2017)
Published in Cancer cell (13.03.2017)
Get full text
Journal Article
Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia
Lopez, Cécile K, Noguera, Esteve, Stavropoulou, Vaia, Robert, Elie, Aid, Zakia, Ballerini, Paola, Bilhou-Nabera, Chrystèle, Lapillonne, Hélène, Boudia, Fabien, Thirant, Cécile, Fagnan, Alexandre, Arcangeli, Marie-Laure, Kinston, Sarah J, Diop, M'Boyba, Job, Bastien, Lecluse, Yann, Brunet, Erika, Babin, Loélia, Villeval, Jean Luc, Delabesse, Eric, Peters, Antoine H F M, Vainchenker, William, Gaudry, Muriel, Masetti, Riccardo, Locatelli, Franco, Malinge, Sébastien, Nerlov, Claus, Droin, Nathalie, Lobry, Camille, Godin, Isabelle, Bernard, Olivier A, Göttgens, Berthold, Petit, Arnaud, Pflumio, Françoise, Schwaller, Juerg, Mercher, Thomas
Published in Cancer discovery (01.12.2019)
Published in Cancer discovery (01.12.2019)
Get full text
Journal Article
CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia
Cardoso, Bruno A, Duque, Mafalda, Gírio, Ana, Fragoso, Rita, Oliveira, Mariana L, Allen, James R, Martins, Leila R, Correia, Nádia C, Silveira, André Bortolini, Veloso, Alexandra, Kimura, Shunsuke, Demoen, Lisa, Matthijssens, Filip, Jeha, Sima, Cheng, Cheng, Pui, Ching-Hon, Grosso, Ana R, Neto, João L, De Almeida, Sérgio F, Van Vlieberghe, Pieter, Mullighan, Charles G, Yunes, J Andres, Langenau, David M, Pflumio, Françoise, Barata, João T
Published in Haematologica (Roma) (01.06.2024)
Published in Haematologica (Roma) (01.06.2024)
Get full text
Journal Article
Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia
Nguyen, Tra Ly, Nokin, Marie‐Julie, Terés, Silvia, Tomé, Mercedes, Bodineau, Clément, Galmar, Oriane, Pasquet, Jean‐Max, Rousseau, Benoit, Liempd, Sebastian, Falcon‐Perez, Juan Manuel, Richard, Elodie, Muzotte, Elodie, Rezvani, Hamid‐Reza, Priault, Muriel, Bouchecareilh, Marion, Redonnet‐Vernhet, Isabelle, Calvo, Julien, Uzan, Benjamin, Pflumio, Françoise, Fuentes, Patricia, Toribio, Maria L., Khatib, Abdel‐Majid, Soubeyran, Pierre, Murdoch, Piedad del Socorro, Durán, Raúl V.
Published in Molecular oncology (01.05.2021)
Published in Molecular oncology (01.05.2021)
Get full text
Journal Article
Web Resource
Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models
Thiollier, Clarisse, Lopez, Cécile K, Gerby, Bastien, Ignacimouttou, Cathy, Poglio, Sandrine, Duffourd, Yannis, Guégan, Justine, Rivera-Munoz, Paola, Bluteau, Olivier, Mabialah, Vinciane, Diop, M'boyba, Wen, Qiang, Petit, Arnaud, Bauchet, Anne-Laure, Reinhardt, Dirk, Bornhauser, Beat, Gautheret, Daniel, Lecluse, Yann, Landman-Parker, Judith, Radford, Isabelle, Vainchenker, William, Dastugue, Nicole, de Botton, Stéphane, Dessen, Philippe, Bourquin, Jean-Pierre, Crispino, John D, Ballerini, Paola, Bernard, Olivier A, Pflumio, Françoise, Mercher, Thomas
Published in The Journal of experimental medicine (22.10.2012)
Published in The Journal of experimental medicine (22.10.2012)
Get full text
Journal Article
The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300‐dependent stemness program
Fagnan, Alexandre, Aid, Zakia, Baille, Marie, Drakul, Aneta, Robert, Elie, Lopez, Cécile K., Thirant, Cécile, Lecluse, Yann, Rivière, Julie, Ignacimouttou, Cathy, Salmoiraghi, Silvia, Anguita, Eduardo, Naimo, Audrey, Marzac, Christophe, Pflumio, Françoise, Malinge, Sébastien, Wichmann, Christian, Huang, Yun, Lobry, Camille, Chaumeil, Julie, Soler, Eric, Bourquin, Jean‐Pierre, Nerlov, Claus, Bernard, Olivier A., Schwaller, Juerg, Mercher, Thomas
Published in HemaSphere (01.06.2024)
Published in HemaSphere (01.06.2024)
Get full text
Journal Article
Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors
Thirant, Cécile, Bessette, Barbara, Varlet, Pascale, Puget, Stéphanie, Cadusseau, Josette, Tavares, Silvina Dos Reis, Studler, Jeanne-Marie, Silvestre, David Carlos, Susini, Aurélie, Villa, Chiara, Miquel, Catherine, Bogeas, Alexandra, Surena, Anne-Laure, Dias-Morais, Amélia, Léonard, Nadine, Pflumio, Françoise, Bièche, Ivan, Boussin, François D, Sainte-Rose, Christian, Grill, Jacques, Daumas-Duport, Catherine, Chneiweiss, Hervé, Junier, Marie-Pierre
Published in PloS one (28.01.2011)
Published in PloS one (28.01.2011)
Get full text
Journal Article
Interleukin‐18 produced by bone marrow‐derived stromal cells supports T‐cell acute leukaemia progression
Uzan, Benjamin, Poglio, Sandrine, Gerby, Bastien, Wu, Ching‐Lien, Gross, Julia, Armstrong, Florence, Calvo, Julien, Cahu, Xavier, Deswarte, Caroline, Dumont, Florent, Passaro, Diana, Besnard‐Guérin, Corinne, Leblanc, Thierry, Baruchel, André, Landman‐Parker, Judith, Ballerini, Paola, Baud, Véronique, Ghysdael, Jacques, Baleydier, Frédéric, Porteu, Francoise, Pflumio, Francoise
Published in EMBO molecular medicine (01.06.2014)
Published in EMBO molecular medicine (01.06.2014)
Get full text
Journal Article
SCL/TAL1 expression level regulates human hematopoietic stem cell self-renewal and engraftment
Reynaud, Damien, Ravet, Emmanuel, Titeux, Monique, Mazurier, Frédéric, Rénia, Laurent, Dubart-Kupperschmitt, Anne, Roméo, Paul-Henri, Pflumio, Françoise
Published in Blood (01.10.2005)
Published in Blood (01.10.2005)
Get full text
Journal Article
The HOXB4 Homeoprotein Differentially Promotes Ex Vivo Expansion of Early Human Lymphoid Progenitors
Haddad, Rima, Pflumio, Françoise, Vigon, Isabelle, Visentin, Géraldine, Auvray, Céline, Fichelson, Serge, Amsellem, Sophie
Published in Stem cells (Dayton, Ohio) (01.02.2008)
Published in Stem cells (Dayton, Ohio) (01.02.2008)
Get full text
Journal Article
Ultra-high-dose-rate FLASH and Conventional-Dose-Rate Irradiation Differentially Affect Human Acute Lymphoblastic Leukemia and Normal Hematopoiesis
Chabi, Sara, To, Thi Hong Van, Leavitt, Ron, Poglio, Sandrine, Jorge, Patrik Gonçalves, Jaccard, Maud, Petersson, Kristoffer, Petit, Benoit, Roméo, Paul-Henri, Pflumio, Françoise, Vozenin, Marie-Catherine, Uzan, Benjamin
Published in International journal of radiation oncology, biology, physics (01.03.2021)
Published in International journal of radiation oncology, biology, physics (01.03.2021)
Get full text
Journal Article
Characterization of DNA-binding-dependent and -independent functions of SCL/TAL1 during human erythropoiesis
Ravet, Emmanuel, Reynaud, Damien, Titeux, Monique, Izac, Brigitte, Fichelson, Serge, Roméo, Paul-Henri, Dubart-Kupperschmitt, Anne, Pflumio, Françoise
Published in Blood (01.05.2004)
Published in Blood (01.05.2004)
Get full text
Journal Article
PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells
Naudin, Cécile, Hattabi, Aurore, Michelet, Fabio, Miri-Nezhad, Ayda, Benyoucef, Aissa, Pflumio, Françoise, Guillonneau, François, Fichelson, Serge, Vigon, Isabelle, Dusanter-Fourt, Isabelle, Lauret, Evelyne
Published in Blood (04.05.2017)
Published in Blood (04.05.2017)
Get full text
Journal Article
Fratricide-resistant CD1a-specific CAR T cells for the treatment of cortical T-cell acute lymphoblastic leukemia
Sánchez-Martínez, Diego, Baroni, Matteo L., Gutierrez-Agüera, Francisco, Roca-Ho, Heleia, Blanch-Lombarte, Oscar, González-García, Sara, Torrebadell, Montserrat, Junca, Jordi, Ramírez-Orellana, Manuel, Velasco-Hernández, Talía, Bueno, Clara, Fuster, José Luís, Prado, Julia G., Calvo, Julien, Uzan, Benjamin, Cools, Jan, Camos, Mireia, Pflumio, Françoise, Toribio, María Luisa, Menéndez, Pablo
Published in Blood (23.05.2019)
Published in Blood (23.05.2019)
Get full text
Journal Article
Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse
Clappier, Emmanuelle, Gerby, Bastien, Sigaux, François, Delord, Marc, Touzri, Farah, Hernandez, Lucie, Ballerini, Paola, Baruchel, André, Pflumio, Françoise, Soulier, Jean
Published in The Journal of experimental medicine (11.04.2011)
Published in The Journal of experimental medicine (11.04.2011)
Get full text
Journal Article