Cytokine receptor signaling is required for the survival of ALK− anaplastic large cell lymphoma, even in the presence of JAK1/STAT3 mutations
Chen, Jing, Zhang, Yong, Petrus, Michael N., Xiao, Wenming, Nicolae, Alina, Raffeld, Mark, Pittaluga, Stefania, Bamford, Richard N., Nakagawa, Masao, Ouyang, Sunny Tianyi, Epstein, Alan L., Kadin, Marshall E., Del Mistro, Annarose, Woessner, Richard, Jaffe, Elaine S., Waldmann, Thomas A.
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2017)
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Essential role of the linear ubiquitin chain assembly complex and TAK1 kinase in A20 mutant Hodgkin lymphoma
Song, Zhihui, Wei, Wei, Xiao, Wenming, Al-Saleem, Essel D., Nejati, Reza, Chen, Liqi, Yin, Jiejing, Fabrizio, Joseph, Petrus, Michael N., Waldmann, Thomas A., Yang, Yibin
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2020)
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Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2–dependent adult T-cell leukemia
Zhang, Meili, Griner, Lesley A. Mathews, Ju, Wei, Duveau, Damien Y., Guha, Rajarshi, Petrus, Michael N., Wen, Bernard, Maeda, Michiyuki, Shinn, Paul, Ferrer, Marc, Conlon, Kevin D., Bamford, Richard N., O’Shea, John J., Thomas, Craig J., Waldmann, Thomas A.
Published in Proceedings of the National Academy of Sciences - PNAS (06.10.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (06.10.2015)
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Augmented efficacy of brentuximab vedotin combined with ruxolitinib and/or Navitoclax in a murine model of human Hodgkin’s lymphoma
Ju, Wei, Zhang, Meili, Wilson, Kelli M., Petrus, Michael N., Bamford, Richard N., Zhang, Xiaohu, Guha, Rajarshi, Ferrer, Marc, Thomas, Craig J., Waldmann, Thomas A.
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (09.02.2016)
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Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases
Bellon, Marcia, Bialuk, Izabela, Galli, Veronica, Bai, Xue-Tao, Farre, Lourdes, Bittencourt, Achilea, Marçais, Ambroise, Petrus, Michael N, Ratner, Lee, Waldmann, Thomas A, Asnafi, Vahid, Gessain, Antoine, Matsuoka, Masao, Franchini, Genoveffa, Hermine, Olivier, Watanabe, Toshiki, Nicot, Christophe
Published in Molecular cancer (06.06.2021)
Published in Molecular cancer (06.06.2021)
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Short-course IL-15 given as a continuous infusion led to a massive expansion of effective NK cells: implications for combination therapy with antitumor antibodies
Dubois, Sigrid P, Miljkovic, Milos D, Fleisher, Thomas A, Pittaluga, Stefania, Hsu-Albert, Jennifer, Bryant, Bonita R, Petrus, Michael N, Perera, Liyanage P, Müller, Jürgen R, Shih, Joanna H, Waldmann, Thomas A, Conlon, Kevin C
Published in Journal for immunotherapy of cancer (01.04.2021)
Published in Journal for immunotherapy of cancer (01.04.2021)
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Enhanced efficacy of JAK1 inhibitor with mTORC1/C2 targeting in smoldering/chronic adult T cell leukemia
Daenthanasanmak, Anusara, Lin, Yuquan, Zhang, Meili, Bryant, Bonita R., Petrus, Michael N., Bamford, Richard N., Thomas, Craig J., Miljkovic, Milos D., Conlon, Kevin C., Waldmann, Thomas A.
Published in Translational oncology (01.01.2021)
Published in Translational oncology (01.01.2021)
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Chimeric antigen receptor modified T cells that target chemokine receptor CCR4 as a therapeutic modality for T‐cell malignancies
Perera, Liyanage P., Zhang, Meili, Nakagawa, Masao, Petrus, Michael N., Maeda, Michiyuki, Kadin, Marshall E., Waldmann, Thomas A., Perera, Pin‐Yu
Published in American journal of hematology (01.09.2017)
Published in American journal of hematology (01.09.2017)
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Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma
Nakagawa, Masao, Shaffer, Arthur L., Ceribelli, Michele, Zhang, Meili, Wright, George, Huang, Da Wei, Xiao, Wenming, Powell, John, Petrus, Michael N., Yang, Yibin, Phelan, James D., Kohlhammer, Holger, Dubois, Sigrid P., Yoo, Hee Min, Bachy, Emmanuel, Webster, Daniel E., Yang, Yandan, Xu, Weihong, Yu, Xin, Zhao, Hong, Bryant, Bonita R., Shimono, Joji, Ishio, Takashi, Maeda, Michiyuki, Green, Patrick L., Waldmann, Thomas A., Staudt, Louis M.
Published in Cancer cell (13.08.2018)
Published in Cancer cell (13.08.2018)
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Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in adult T-cell leukemia/lymphoma
Ishio, Takashi, Kumar, Sarvesh, Shimono, Joji, Daenthanasanmak, Anusara, Dubois, Sigrid, Lin, Yuquan, Bryant, Bonita, Petrus, Michael N., Bachy, Emmanuel, Huang, Da Wei, Yang, Yandan, Green, Patrick L., Hasegawa, Hiroo, Maeda, Michiyuki, Goto, Hideki, Endo, Tomoyuki, Yokota, Takashi, Hatanaka, Kanako C., Hatanaka, Yutaka, Tanaka, Shinya, Matsuno, Yoshihiro, Yang, Yibin, Hashino, Satoshi, Teshima, Takanori, Waldmann, Thomas A., Staudt, Louis M., Nakagawa, Masao
Published in Blood (10.03.2022)
Published in Blood (10.03.2022)
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A novel model of alternative NF-κB pathway activation in anaplastic large cell lymphoma
Wang, Hongbo, Wei, Wei, Zhang, Jing-Ping, Song, Zhihui, Li, Yangyang, Xiao, Wenming, Liu, Yijun, Zeng, Mu-Sheng, Petrus, Michael N, Thomas, Craig J, Kadin, Marshall E, Nakagawa, Masao, Waldmann, Thomas A, Yang, Yibin
Published in Leukemia (01.07.2021)
Published in Leukemia (01.07.2021)
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IL-2 receptors preassemble and signal in the ER/Golgi causing resistance to antiproliferative anti–IL-2Rα therapies
Volkó, Julianna, Kenesei, Ádám, Zhang, Meili, Várnai, Péter, Mocsár, Gábor, Petrus, Michael N., Jambrovics, Károly, Balajthy, Zoltán, Müller, Gabriele, Bodnár, Andrea, Tóth, Katalin, Waldmann, Thomas A., Vámosi, György
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2019)
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Phase 1 trial of IL-15 trans presentation blockade using humanized Mik-Beta-1 mAb in patients with T-cell large granular lymphocytic leukemia
Waldmann, Thomas A., Conlon, Kevin C., Stewart, Donn M., Worthy, TatYana A., Janik, John E., Fleisher, Thomas A., Albert, Paul S., Figg, William D., Spencer, Shawn D., Raffeld, Mark, Decker, Jean R., Goldman, Carolyn K., Bryant, Bonita R., Petrus, Michael N., Creekmore, Stephen P., Morris, John C.
Published in Blood (17.01.2013)
Published in Blood (17.01.2013)
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Triple combination of BET plus PI3K and NF-κB inhibitors exhibit synergistic activity in adult T-cell leukemia/lymphoma
Daenthanasanmak, Anusara, Bamford, Richard N., Yoshioka, Makoto, Yang, Shyh-Ming, Homan, Philip, Karim, Baktiar, Bryant, Bonita R., Petrus, Michael N., Thomas, Craig J., Green, Patrick L., Miljkovic, Milos D., Conlon, Kevin C., Waldmann, Thomas A.
Published in Blood advances (12.04.2022)
Published in Blood advances (12.04.2022)
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Development of an IL-15–autocrine CD8 T-cell leukemia in IL-15–transgenic mice requires the cis expression of IL-15Rα
Sato, Noriko, Sabzevari, Helen, Fu, Song, Ju, Wei, Petrus, Michael N., Bamford, Richard N., Waldmann, Thomas A., Tagaya, Yutaka
Published in Blood (14.04.2011)
Published in Blood (14.04.2011)
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A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling
Nguyen, Vinh-Phuc, Chen, Jing, Petrus, Michael N, Goldman, Carolyn K, Kruhlak, Michael J, Bamford, Richard N, Waldmann, Thomas A
Published in Journal of innate immunity (2014)
Published in Journal of innate immunity (2014)
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A20 and RBX1 regulate brentuximab vedotin sensitivity in Hodgkin Lymphoma identified by a sensitization CRISPR screen
Wei, Wei, Lin, Yuquan, Song, Zhihui, Xiao, Wenming, Chen, Liqi, Yin, Jiejing, Zhou, Yan, Barta, Stefan K., Petrus, Michael N., Waldmann, Thomas A., Yang, Yibin
Published in Clinical cancer research (16.04.2020)
Published in Clinical cancer research (16.04.2020)
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A novel model of alternative NF-[kappa]B pathway activation in anaplastic large cell lymphoma
Wang, Hongbo, Wei, Wei, Zhang, Jing-Ping, Song, Zhihui, Li, Yangyang, Xiao, Wenming, Liu, Yijun, Zeng, Mu-Sheng, Petrus, Michael N, Thomas, Craig J, Kadin, Marshall E, Nakagawa, Masao, Waldmann, Thomas A, Yang, Yibin
Published in Leukemia (01.07.2021)
Published in Leukemia (01.07.2021)
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Genome-Wide CRISPR Library Screening Identifies CDK6 As Genetic Vulnerability in Adult T-Cell Leukemia/Lymphoma
Ishio, Takashi, Shimono, Joji, Kumar, Sarvesh, Lin, Yuquan, Bachy, Emmanuel, Petrus, Michael N., Yang, Yandan, Maeda, Michiyuki, Goto, Hideki, Hashino, Satoshi, Teshima, Takanori, Waldmann, Thomas A., Staudt, Louis, Nakagawa, Masao
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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IL-15 by continuous i.v. infusion to adult patients with solid tumors in a Phase I trial induced dramatic NK cell subset expansion
Conlon, Kevin C., Potter, E. Lake, Pittaluga, Stefania, Lee, Chyi-Chia Richard, Miljkovic, Milos D., Fleisher, Thomas A., Dubois, Sigrid, Bryant, Bonita R., Petrus, Michael N., Perera, Liyanage P., Hsu, Jennifer, Figg, William D., Peer, Cody J., Shih, Joanna H., Yovandich, Jason L., Creekmore, Stephen P., Roederer, Mario, Waldmann, Thomas A.
Published in Clinical cancer research (29.05.2019)
Published in Clinical cancer research (29.05.2019)
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