Structural biology of the Bcl-2 family of proteins
Petros, Andrew M., Olejniczak, Edward T., Fesik, Stephen W.
Published in BBA - Molecular Cell Research (01.03.2004)
Published in BBA - Molecular Cell Research (01.03.2004)
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An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Fesik, Stephen W, Rosenberg, Saul H, Oltersdorf, Tilman, Elmore, Steven W, Shoemaker, Alexander R, Armstrong, Robert C, Augeri, David J, Belli, Barbara A, Bruncko, Milan, Deckwerth, Thomas L, Dinges, Jurgen, Hajduk, Philip J, Joseph, Mary K, Kitada, Shinichi, Korsmeyer, Stanley J, Kunzer, Aaron R, Letai, Anthony, Li, Chi, Mitten, Michael J, Nettesheim, David G, Ng, ShiChung, Nimmer, Paul M, O'Connor, Jacqueline M, Oleksijew, Anatol, Petros, Andrew M, Reed, John C, Shen, Wang, Tahir, Stephen K, Thompson, Craig B, Tomaselli, Kevin J, Wang, Baole, Wendt, Michael D, Zhang, Haichao
Published in Nature (02.06.2005)
Published in Nature (02.06.2005)
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Journal Article
Discovery of a potent inhibitor of the antiapoptotic protein Bcl-x(L) from NMR and parallel synthesis
Petros, AM, Dinges, J, Augeri, DJ, Baumeister, SA, Betebenner, DA, Bures, MG, Elmore, SW, Hajduk, PJ, Joseph, MK, Landis, SK, Nettesheim, DG, Rosenberg, SH, Shen, W, Thomas, S, Wang, XL, Zanze, Zhang, HC, Fesik, SW
Published in Journal of medicinal chemistry (26.01.2006)
Published in Journal of medicinal chemistry (26.01.2006)
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Journal Article
Structure of the N-Terminal RNA-Binding Domain of the SARS CoV Nucleocapsid Protein
Huang, Qiulong, Yu, Liping, Petros, Andrew M, Gunasekera, Angelo, Liu, Zhihong, Xu, Nan, Hajduk, Philip, Mack, Jamey, Fesik, Stephen W, Olejniczak, Edward T
Published in Biochemistry (Easton) (25.05.2004)
Published in Biochemistry (Easton) (25.05.2004)
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Journal Article
Solution Structure of the Antiapoptotic Protein bcl-2
Petros, Andrew M., Medek, Ales, Nettesheim, David G., Kim, Daniel H., Yoon, Ho Sup, Swift, Kerry, Matayoshi, Edmund D., Oltersdorf, Tilman, Fesik, Stephen W.
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2001)
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Journal Article
Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo
Wendt, Michael D, Shen, Wang, Kunzer, Aaron, McClellan, William J, Bruncko, Milan, Oost, Thorsten K, Ding, Hong, Joseph, Mary K, Zhang, Haichao, Nimmer, Paul M, Ng, Shi-Chung, Shoemaker, Alexander R, Petros, Andrew M, Oleksijew, Anatol, Marsh, Kennan, Bauch, Joy, Oltersdorf, Tilman, Belli, Barbara A, Martineau, Darlene, Fesik, Stephen W, Rosenberg, Saul H, Elmore, Steven W
Published in Journal of medicinal chemistry (09.02.2006)
Published in Journal of medicinal chemistry (09.02.2006)
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Journal Article
Discovery of novel inhibitors of Bcl-xL using multiple high-throughput screening platforms
Qian, Jie, Voorbach, Martin J, Huth, Jeffrey R, Coen, Michael L, Zhang, Haichao, Ng, Shi-Chung, Comess, Kenneth M, Petros, Andrew M, Rosenberg, Saul H, Warrior, Usha, Burns, David J
Published in Analytical biochemistry (15.05.2004)
Published in Analytical biochemistry (15.05.2004)
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Journal Article
Structure and ligand recognition of the phosphotyrosine binding domain of Shc
Zhou, Ming-Ming, Ravichandran, Kodimangalam S, Olejniczak, Edward T, Petros, Andrew M, Meadows, Robert P, Sattler, Michael, Harlan, John E, Wade, Warren S, Burakoff, Steven J, Fesik, Stephen W
Published in Nature (London) (07.12.1995)
Published in Nature (London) (07.12.1995)
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Journal Article
Solution structure of a pleckstrin-homology domain
Yoon, Ho Sup, Hajduk, Philip J, Petros, Andrew M, Olejniczak, Edward T, Meadows, Robert P, Fesik, Stephen W
Published in Nature (London) (23.06.1994)
Published in Nature (London) (23.06.1994)
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Journal Article
Divergence of Genbank and human tumor Bcl-2 sequences and implications for binding affinity to key apoptotic proteins
JOSEPH, Mary K, SOLOMON, Larry R, PETROS, Andrew M, CAI, Jill, SIMMER, Robert L, HAICHAO ZHANG, ROSENBERG, Saul, NG, Shi-Chung
Published in Oncogene (22.01.2004)
Published in Oncogene (22.01.2004)
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Journal Article
Solution Structure of the DNA-Binding Domain of a Human Papillomavirus E2 Protein: Evidence for Flexible DNA-Binding Regions
Liang, Heng, Petros, Andrew M, Meadows, Robert P, Yoon, Ho Sup, Egan, David A, Walter, Karl, Holzman, Thomas F, Robins, Terry, Fesik, Stephen W
Published in Biochemistry (Easton) (20.02.1996)
Published in Biochemistry (Easton) (20.02.1996)
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Journal Article
Solution Structure of the Amino-Terminal Fragment of Urokinase-Type Plasminogen Activator
Hansen, Andrew P, Petros, Andrew M, Meadows, Robert P, Nettesheim, David G, Mazar, Andrew P, Olejniczak, Edward T, Xu, Robert X, Pederson, Terry M, Henkin, Jack, Fesik, Stephen W
Published in Biochemistry (Easton) (01.04.1994)
Published in Biochemistry (Easton) (01.04.1994)
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Journal Article
NMR identification of protein surfaces using paramagnetic probes
Petros, Andrew M, Mueller, Luciano, Kopple, Kenneth D
Published in Biochemistry (Easton) (01.10.1990)
Published in Biochemistry (Easton) (01.10.1990)
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Journal Article
Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance
Yu, L, Petros, A M, Schnuchel, A, Zhong, P, Severin, J M, Walter, K, Holzman, T F, Fesik, S W
Published in Nature structural biology (01.06.1997)
Published in Nature structural biology (01.06.1997)
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