Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer
Galvani, Elena, Alfieri, Roberta, Giovannetti, Elisa, Cavazzoni, Andrea, La Monica, Silvia, Galetti, Maricla, Fumarola, Claudia, Bonelli, Mara, Mor, Marco, Tiseo, Marcello, Peters, Godefridus J, Petronini, Pier Giorgio, Ardizzoni, Andrea
Published in Current pharmaceutical design (01.02.2013)
Published in Current pharmaceutical design (01.02.2013)
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Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer
Fumarola, Claudia, Bonelli, Mara A., Petronini, Pier Giorgio, Alfieri, Roberta R.
Published in Biochemical pharmacology (01.08.2014)
Published in Biochemical pharmacology (01.08.2014)
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Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines
Cavazzoni, Andrea, Alfieri, Roberta R, Cretella, Daniele, Saccani, Francesca, Ampollini, Luca, Galetti, Maricla, Quaini, Federico, Graiani, Gallia, Madeddu, Denise, Mozzoni, Paola, Galvani, Elena, La Monica, Silvia, Bonelli, Mara, Fumarola, Claudia, Mutti, Antonio, Carbognani, Paolo, Tiseo, Marcello, Barocelli, Elisabetta, Petronini, Pier Giorgio, Ardizzoni, Andrea
Published in Molecular cancer (12.12.2012)
Published in Molecular cancer (12.12.2012)
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Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines
Eltayeb, Kamal, Alfieri, Roberta, Fumarola, Claudia, Bonelli, Mara, Galetti, Maricla, Cavazzoni, Andrea, Digiacomo, Graziana, Galvani, Francesca, Vacondio, Federica, Lodola, Alessio, Mor, Marco, Minari, Roberta, Tiseo, Marcello, La Monica, Silvia, Giorgio Petronini, Pier
Published in Biochemical pharmacology (01.10.2024)
Published in Biochemical pharmacology (01.10.2024)
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Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells
Bonelli, Mara A., Digiacomo, Graziana, Fumarola, Claudia, Alfieri, Roberta, Quaini, Federico, Falco, Angela, Madeddu, Denise, La Monica, Silvia, Cretella, Daniele, Ravelli, Andrea, Ulivi, Paola, Tebaldi, Michela, Calistri, Daniele, Delmonte, Angelo, Ampollini, Luca, Carbognani, Paolo, Tiseo, Marcello, Cavazzoni, Andrea, Petronini, Pier Giorgio
Published in Neoplasia (New York, N.Y.) (01.08.2017)
Published in Neoplasia (New York, N.Y.) (01.08.2017)
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The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells
Cretella, Daniele, Ravelli, Andrea, Fumarola, Claudia, La Monica, Silvia, Digiacomo, Graziana, Cavazzoni, Andrea, Alfieri, Roberta, Biondi, Alessandra, Generali, Daniele, Bonelli, Mara, Petronini, Pier Giorgio
Published in Journal of experimental & clinical cancer research (27.03.2018)
Published in Journal of experimental & clinical cancer research (27.03.2018)
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Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines
La Monica, Silvia, Cretella, Daniele, Bonelli, Mara, Fumarola, Claudia, Cavazzoni, Andrea, Digiacomo, Graziana, Flammini, Lisa, Barocelli, Elisabetta, Minari, Roberta, Naldi, Nadia, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Published in Journal of experimental & clinical cancer research (04.12.2017)
Published in Journal of experimental & clinical cancer research (04.12.2017)
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FGFR as potential target in the treatment of squamous non small cell lung cancer
Tiseo, Marcello, Gelsomino, Francesco, Alfieri, Roberta, Cavazzoni, Andrea, Bozzetti, Cecilia, De Giorgi, Anna Maria, Petronini, Pier Giorgio, Ardizzoni, Andrea
Published in Cancer treatment reviews (01.06.2015)
Published in Cancer treatment reviews (01.06.2015)
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Dual Inhibition of CDK4/6 and PI3K/AKT/mTOR Signaling Impairs Energy Metabolism in MPM Cancer Cells
Bonelli, Mara, Terenziani, Rita, Zoppi, Silvia, Fumarola, Claudia, La Monica, Silvia, Cretella, Daniele, Alfieri, Roberta, Cavazzoni, Andrea, Digiacomo, Graziana, Galetti, Maricla, Petronini, Pier Giorgio
Published in International journal of molecular sciences (21.07.2020)
Published in International journal of molecular sciences (21.07.2020)
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Tumor-infiltrating lymphocytes and breast cancer: Beyond the prognostic and predictive utility
Ravelli, Andrea, Roviello, Giandomenico, Cretella, Daniele, Cavazzoni, Andrea, Biondi, Alessandra, Cappelletti, Maria Rosa, Zanotti, Laura, Ferrero, Giuseppina, Ungari, Marco, Zanconati, Fabrizio, Bottini, Alberto, Alfieri, Roberta, Petronini, Pier Giorgio, Generali, Daniele
Published in Tumor Biology (01.04.2017)
Published in Tumor Biology (01.04.2017)
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A New ABCB1 Inhibitor Enhances the Anticancer Effect of Doxorubicin in Both In Vitro and In Vivo Models of NSCLC
Adorni, Maria Pia, Galetti, Maricla, La Monica, Silvia, Incerti, Matteo, Ruffoni, Alessandro, Elviri, Lisa, Zanotti, Ilaria, Papotti, Bianca, Cavallo, Delia, Alfieri, Roberta, Petronini, Pier Giorgio, Bernini, Franco
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Published in International journal of molecular sciences (04.01.2023)
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Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models
La Monica, Silvia, Vacondio, Federica, Eltayeb, Kamal, Lodola, Alessio, Volta, Francesco, Viglioli, Martina, Ferlenghi, Francesca, Galvani, Francesca, Galetti, Maricla, Bonelli, Mara, Fumarola, Claudia, Cavazzoni, Andrea, Flammini, Lisa, Verzè, Michela, Minari, Roberta, Petronini, Pier Giorgio, Tiseo, Marcello, Mor, Marco, Alfieri, Roberta
Published in Scientific reports (18.03.2024)
Published in Scientific reports (18.03.2024)
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Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines
Galetti, Maricla, Petronini, Pier Giorgio, Fumarola, Claudia, Cretella, Daniele, La Monica, Silvia, Bonelli, Mara, Cavazzoni, Andrea, Saccani, Francesca, Caffarra, Cristina, Andreoli, Roberta, Mutti, Antonio, Tiseo, Marcello, Ardizzoni, Andrea, Alfieri, Roberta R
Published in PloS one (04.11.2015)
Published in PloS one (04.11.2015)
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Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC
La Monica, Silvia, Minari, Roberta, Cretella, Daniele, Flammini, Lisa, Fumarola, Claudia, Bonelli, Mara, Cavazzoni, Andrea, Digiacomo, Graziana, Galetti, Maricla, Madeddu, Denise, Falco, Angela, Lagrasta, Costanza Annamaria, Squadrilli, Anna, Barocelli, Elisabetta, Romanel, Alessandro, Quaini, Federico, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
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Published in Journal of experimental & clinical cancer research (28.05.2019)
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CDK4/6 inhibitors in HER2-positive breast cancer
Corona, Silvia Paola, Ravelli, Andrea, Cretella, Daniele, Cappelletti, Maria Rosa, Zanotti, Laura, Dester, Martina, Gobbi, Angela, Petronini, Pier Giorgio, Generali, Daniele
Published in Critical reviews in oncology/hematology (01.04.2017)
Published in Critical reviews in oncology/hematology (01.04.2017)
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A Photoactive Supramolecular Complex Targeting PD-L1 Reveals a Weak Correlation between Photoactivation Efficiency and Receptor Expression Levels in Non-Small-Cell Lung Cancer Tumor Models
Delcanale, Pietro, Alampi, Manuela Maria, Mussini, Andrea, Fumarola, Claudia, Galetti, Maricla, Petronini, Pier Giorgio, Viappiani, Cristiano, Bruno, Stefano, Abbruzzetti, Stefania
Published in Pharmaceutics (01.12.2023)
Published in Pharmaceutics (01.12.2023)
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Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion
La Monica, Silvia, Minari, Roberta, Cretella, Daniele, Bonelli, Mara, Fumarola, Claudia, Cavazzoni, Andrea, Galetti, Maricla, Digiacomo, Graziana, Riccardi, Federica, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Published in Targeted oncology (01.10.2019)
Published in Targeted oncology (01.10.2019)
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Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines
Digiacomo, Graziana, Fumarola, Claudia, La Monica, Silvia, Bonelli, Mara A., Cretella, Daniele, Alfieri, Roberta, Cavazzoni, Andrea, Galetti, Maricla, Bertolini, Patrizia, Missale, Gabriele, Petronini, Pier Giorgio
Published in Frontiers in oncology (23.09.2020)
Published in Frontiers in oncology (23.09.2020)
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Effects of sorafenib on energy metabolism in breast cancer cells: role of AMPK–mTORC1 signaling
Fumarola, Claudia, Caffarra, Cristina, La Monica, Silvia, Galetti, Maricla, Alfieri, Roberta R., Cavazzoni, Andrea, Galvani, Elena, Generali, Daniele, Petronini, Pier Giorgio, Bonelli, Mara A.
Published in Breast cancer research and treatment (01.08.2013)
Published in Breast cancer research and treatment (01.08.2013)
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CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells
Digiacomo, Graziana, Fumarola, Claudia, La Monica, Silvia, Bonelli, Mara, Cavazzoni, Andrea, Galetti, Maricla, Terenziani, Rita, Eltayeb, Kamal, Volta, Francesco, Zoppi, Silvia, Bertolini, Patrizia, Missale, Gabriele, Alfieri, Roberta, Petronini, Pier Giorgio
Published in Frontiers in oncology (22.07.2022)
Published in Frontiers in oncology (22.07.2022)
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