Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
Lovejoy, Courtney A, Li, Wendi, Reisenweber, Steven, Thongthip, Supawat, Bruno, Joanne, de Lange, Titia, De, Saurav, Petrini, John H J, Sung, Patricia A, Jasin, Maria, Rosenbluh, Joseph, Zwang, Yaara, Weir, Barbara A, Hatton, Charlie, Ivanova, Elena, Macconaill, Laura, Hanna, Megan, Hahn, William C, Lue, Neal F, Reddel, Roger R, Jiao, Yuchen, Kinzler, Kenneth, Vogelstein, Bert, Papadopoulos, Nickolas, Meeker, Alan K
Published in PLoS genetics (01.07.2012)
Published in PLoS genetics (01.07.2012)
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RTEL1 influences the abundance and localization of TERRA RNA
Ghisays, Fiorella, Garzia, Aitor, Wang, Hexiao, Canasto-Chibuque, Claudia, Hohl, Marcel, Savage, Sharon A., Tuschl, Thomas, Petrini, John H. J.
Published in Nature communications (21.05.2021)
Published in Nature communications (21.05.2021)
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Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis
Hohl, Marcel, Mojumdar, Aditya, Hailemariam, Sarem, Kuryavyi, Vitaly, Ghisays, Fiorella, Sorenson, Kyle, Chang, Matthew, Taylor, Barry S, Patel, Dinshaw J, Burgers, Peter M, Cobb, Jennifer A, Petrini, John H J
Published in PLoS genetics (18.03.2020)
Published in PLoS genetics (18.03.2020)
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The MRE11 complex: starting from the ends
Stracker, Travis H, Petrini, John H. J
Published in Nature reviews. Molecular cell biology (01.02.2011)
Published in Nature reviews. Molecular cell biology (01.02.2011)
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The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex
Hussein, Hussein, Stracker, Travis H, Petrini, John H. J, Morales, Monica, Couto, Suzana S
Published in Nature (10.05.2007)
Published in Nature (10.05.2007)
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The Mre11 Complex and the Response to Dysfunctional Telomeres
Attwooll, Claire L., Akpınar, Müge, Petrini, John H. J.
Published in Molecular and Cellular Biology (01.10.2009)
Published in Molecular and Cellular Biology (01.10.2009)
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The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair
Petrini, John H. J, Tainer, John A, Hopfner, Karl-Peter, Craig, Lisa, Moncalian, Gabriel, Zinkel, Robert A, Usui, Takehiko, Owen, Barbara A. L, Karcher, Annette, Henderson, Brendan, Bodmer, Jean-Luc, McMurray, Cynthia T, Carney, James P
Published in Nature (London) (01.08.2002)
Published in Nature (London) (01.08.2002)
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Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells
Wohlbold, Lara, Merrick, Karl A, De, Saurav, Amat, Ramon, Kim, Jun Hyun, Larochelle, Stéphane, Allen, Jasmina J, Zhang, Chao, Shokat, Kevan M, Petrini, John H J, Fisher, Robert P
Published in PLoS genetics (01.08.2012)
Published in PLoS genetics (01.08.2012)
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The structure-selective endonucleases GEN1 and MUS81 mediate complementary functions in safeguarding the genome of proliferating B lymphocytes
Fernandez, Keith Conrad, Feeney, Laura, Smolkin, Ryan M, Yen, Wei-Feng, Matthews, Allysia J, Alread, William, Petrini, John H J, Chaudhuri, Jayanta
Published in eLife (03.10.2022)
Published in eLife (03.10.2022)
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Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes
Katyal, Sachin, Lee, Youngsoo, Nitiss, Karin C, Downing, Susanna M, Li, Yang, Shimada, Mikio, Zhao, Jingfeng, Russell, Helen R, Petrini, John H J, Nitiss, John L, McKinnon, Peter J
Published in Nature neuroscience (01.06.2014)
Published in Nature neuroscience (01.06.2014)
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Srs2 and Sgs1 DNA Helicases Associate with Mre11 in Different Subcomplexes following Checkpoint Activation and CDK1-Mediated Srs2 Phosphorylation
Chiolo, Irene, Carotenuto, Walter, Maffioletti, Giulio, Petrini, John H. J., Foiani, Marco, Liberi, Giordano
Published in Molecular and Cellular Biology (01.07.2005)
Published in Molecular and Cellular Biology (01.07.2005)
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A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome
Ballew, Bari J, Joseph, Vijai, De, Saurav, Sarek, Grzegorz, Vannier, Jean-Baptiste, Stracker, Travis, Schrader, Kasmintan A, Small, Trudy N, O'Reilly, Richard, Manschreck, Chris, Harlan Fleischut, Megan M, Zhang, Liying, Sullivan, John, Stratton, Kelly, Yeager, Meredith, Jacobs, Kevin, Giri, Neelam, Alter, Blanche P, Boland, Joseph, Burdett, Laurie, Offit, Kenneth, Boulton, Simon J, Savage, Sharon A, Petrini, John H J
Published in PLoS genetics (01.08.2013)
Published in PLoS genetics (01.08.2013)
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