Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine
G M Bores, F P Huger, W Petko, A E Mutlib, F Camacho, D K Rush, D E Selk, V Wolf, R W Kosley, Jr, L Davis, H M Vargas
Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
Get full text
Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
Journal Article
Synthesis and Structure−Activity Relationships of N-Propyl-N-(4-pyridinyl)-1H-indol-1-amine (Besipirdine) and Related Analogs as Potential Therapeutic Agents for Alzheimer's Disease
Klein, Joseph T, Davis, Larry, Olsen, Gordon E, Wong, George S, Huger, Francis P, Smith, Craig P, Petko, Wayne W, Cornfeldt, Michael, Wilker, Jeffrey C, Blitzer, R. D, Landau, E, Haroutunian, V, Martin, Lawrence L, Effland, Richard C
Published in Journal of medicinal chemistry (19.01.1996)
Published in Journal of medicinal chemistry (19.01.1996)
Get full text
Journal Article
Substituted (Pyrroloamino)pyridines: Potential Agents for the Treatment of Alzheimer's Disease
Davis, Larry, Klein, Joseph T, Kapples, Kevin J, Huger, Francis P, Smith, Craig P, Petko, Wayne W, Cornfeldt, Michael, Effland, Richard C
Published in Journal of medicinal chemistry (19.01.1996)
Published in Journal of medicinal chemistry (19.01.1996)
Get full text
Journal Article
Synthesis and preliminary structure-activity relationships of 1-[(3-fluoro-4-pyridinyl)amino]-3-methyl-1H-indol-5-yl methyl carbamate (P10358), a novel acetylcholinesterase inhibitor
Martin, Lawrence L., Davis, Larry, Klein, Joseph T., Nemoto, Peter, Olsen, Gordon E., Bores, Gina M., Camacho, Fernando, Petko, Wayne W., Rush, Douglas K., Selk, David, Smith, Craig P., Vargas, Hugo M., Winslow, James T., Effland, Richard C., Fink, David M.
Published in Bioorganic & medicinal chemistry letters (21.01.1997)
Published in Bioorganic & medicinal chemistry letters (21.01.1997)
Get full text
Journal Article
Serotonergic activity of HP 184: does spontaneous release have a role?
Smith, C P, Woods-Kettelberger, A T, Corbett, R, Chesson, S M, Bores, G M, Petko, W W, Roehr, J E, Kongsamut, S
Published in Neurochemical research (01.05.1996)
Published in Neurochemical research (01.05.1996)
Get more information
Journal Article
3-substituted-1,2-benzisoxazoles: novel antipsychotic agents
Davis, L, Effland, R C, Klein, J T, Dunn, R W, Geyer, 3rd, H M, Petko, W W
Published in Drug design and discovery (01.02.1992)
Get more information
Published in Drug design and discovery (01.02.1992)
Journal Article
Imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates as dual inhibitors of acetylcholinesterase and monoamine oxidase
Fink, David M., Palermo, M.G., Bores, Gina M., Huger, Francis P., Kurys, Barbara E., Merriman, Michael C., Olsen, Gordon E., Petko, Wayne, O'Malley, Gerard J.
Published in Bioorganic & medicinal chemistry letters (19.03.1996)
Published in Bioorganic & medicinal chemistry letters (19.03.1996)
Get full text
Journal Article
Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex
Ringheim, Garth E, Szczepanik, Ann Marie, Petko, Wayne, Burgher, Kendra L, Zhu, Sheng Zu, Chao, Chun C
Published in Brain research. Molecular brain research. (30.03.1998)
Published in Brain research. Molecular brain research. (30.03.1998)
Get full text
Journal Article
Pharmacological activity and safety profile of P10358, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease
Smith, C P, Bores, G M, Petko, W, Li, M, Selk, D E, Rush, D K, Camacho, F, Winslow, J T, Fishkin, R, Cunningham, D M, Brooks, K M, Roehr, J, Hartman, H B, Davis, L, Vargas, H M
Published in The Journal of pharmacology and experimental therapeutics (01.02.1997)
Get full text
Published in The Journal of pharmacology and experimental therapeutics (01.02.1997)
Journal Article
Transcriptional Inhibition of the Beta-Amyloid Precursor Protein by Interferon-Gamma
Ringheim, Garth E., Szcepanik, Ann Marie, Burgher, Kendra L., Petko, Wayne, Heroux, Jeffrey A., Cavalieri, Filippo
Published in Biochemical and biophysical research communications (05.07.1996)
Published in Biochemical and biophysical research communications (05.07.1996)
Get full text
Journal Article
AMINOPYRIDINE CARBAMIC ACID-ESTERS - SYNTHESIS AND POTENTIAL AS ACETYLCHOLINESTERASE INHIBITORS AND ACETYLCHOLINE RELEASERS
SHUTSKE, GM, TOMER, JD, KAPPLES, KJ, HRIB, NJ, JURCAK, JG, BORES, GM, HUGER, FP, PETKO, W, SMITH, CP
Published in Journal of pharmaceutical sciences (01.04.1992)
Published in Journal of pharmaceutical sciences (01.04.1992)
Get more information
Journal Article
Synthesis and Structure−Activity Relationships of N -Propyl- N -(4-pyridinyl)-1 H -indol-1-amine (Besipirdine) and Related Analogs as Potential Therapeutic Agents for Alzheimer's Disease
Klein, Joseph T., Davis, Larry, Olsen, Gordon E., Wong, George S., Huger, Francis P., Smith, Craig P., Petko, Wayne W., Cornfeldt, Michael, Wilker, Jeffrey C., Blitzer, R. D., Landau, E., Haroutunian, V., Martin, Lawrence L., Effland, Richard C.
Published in Journal of medicinal chemistry (01.01.1996)
Published in Journal of medicinal chemistry (01.01.1996)
Get full text
Journal Article