Design, Synthesis, Biological Evaluation, and Structure–Activity Relationships of Substituted Phenyl 4-(2-Oxoimidazolidin-1-yl)benzenesulfonates as New Tubulin Inhibitors Mimicking Combretastatin A-4
Fortin, Sébastien, Wei, Lianhu, Moreau, Emmanuel, Lacroix, Jacques, Côté, Marie-France, Petitclerc, Éric, Kotra, Lakshmi P, C.-Gaudreault, René
Published in Journal of medicinal chemistry (14.07.2011)
Published in Journal of medicinal chemistry (14.07.2011)
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Proteolytic Exposure of a Cryptic Site within Collagen Type IV Is Required for Angiogenesis and Tumor Growth in vivo
Xu, Jingsong, Rodriguez, Dorothy, Petitclerc, Eric, Kim, Jenny J., Hangai, Masanori, Yuen, S. Moon, Davis, George E., Brooks, Peter C.
Published in The Journal of cell biology (03.09.2001)
Published in The Journal of cell biology (03.09.2001)
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Plasminogen Activator Inhibitor-1 Regulates Tumor Growth and Angiogenesis
McMahon, Grainne A., Petitclerc, Eric, Stefansson, Steingrimur, Smith, Elizabeth, Wong, Michael K.K., Westrick, Randal J., Ginsburg, David, Brooks, Peter C., Lawrence, Daniel A.
Published in The Journal of biological chemistry (07.09.2001)
Published in The Journal of biological chemistry (07.09.2001)
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Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation
FORTIN, Jessica S, COTE, Marie-France, LACROIX, Jacques, PATENAUDE, Alexandre, PETITCLERC, Eric, GAUDREAULT, René C
Published in Bioorganic & medicinal chemistry letters (15.06.2008)
Published in Bioorganic & medicinal chemistry letters (15.06.2008)
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Microtubule-Destabilizing Agents Induce Focal Adhesion Structure Disorganization and Anoikis in Cancer Cells
Deschesnes, Réna G, Patenaude, Alexandre, Rousseau, Jean L C, Fortin, Jessica S, Ricard, Christine, Côté, Marie-France, Huot, Jacques, C-Gaudreault, René, Petitclerc, Eric
Published in The Journal of pharmacology and experimental therapeutics (01.02.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2007)
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Antiangiogenic and antitumoral activity of phenyl-3-(2-chloroethyl)ureas: A class of soft alkylating agents disrupting microtubules that are unaffected by cell adhesion-mediated drug resistance
PETITCLERC, Eric, DESCHESNES, Réna G, C.-GAUDREAULT, René, COTE, Marie-France, MARQUIS, Claude, JANVIER, Richard, LACROIX, Jacques, MIOT-NOIRAULT, Elisabeth, LEGAULT, Jean, MOUNETOU, Emmanuelle, MADELMONT, Jean-Claude
Published in Cancer research (Chicago, Ill.) (01.07.2004)
Published in Cancer research (Chicago, Ill.) (01.07.2004)
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ASK1-P38 pathway is important for anoikis induced by microtubule-targeting aryl chloroethylureas
Fortin, Jessica, Patenaude, Alexandre, Deschesnes, Réna G, Côté, Marie-France, Petitclerc, Eric, C-Gaudreault, René
Published in Journal of pharmacy & pharmaceutical sciences (01.01.2010)
Published in Journal of pharmacy & pharmaceutical sciences (01.01.2010)
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Journal Article
Quick and Simple Detection Technique to Assess the Binding of Antimicrotubule Agents to the Colchicine-Binding Site
Fortin, Sébastien, Lacroix, Jacques, Côté, Marie-France, Moreau, Emmanuel, Petitclerc, Éric, C.-Gaudreault, René
Published in Biological procedures online (08.04.2010)
Published in Biological procedures online (08.04.2010)
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Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships
Fortin, Sébastien, Wei, Lianhu, Moreau, Emmanuel, Lacroix, Jacques, Côté, Marie-France, Petitclerc, Éric, Kotra, Lakshmi P., Gaudreault, René C.
Published in European journal of medicinal chemistry (01.11.2011)
Published in European journal of medicinal chemistry (01.11.2011)
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Journal Article
Alkylation potency and protein specificity of aromatic urea derivatives and bioisosteres as potential irreversible antagonists of the colchicine-binding site
Fortin, Jessica S., Lacroix, Jacques, Desjardins, Michel, Patenaude, Alexandre, Petitclerc, Éric, C.-Gaudreault, René
Published in Bioorganic & medicinal chemistry (01.07.2007)
Published in Bioorganic & medicinal chemistry (01.07.2007)
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Synthesis, antiproliferative activity evaluation and structure–activity relationships of novel aromatic urea and amide analogues of N-phenyl- N′-(2-chloroethyl)ureas
Fortin, Sébastien, Moreau, Emmanuel, Lacroix, Jacques, Côté, Marie-France, Petitclerc, Éric, C.-Gaudreault, René
Published in European journal of medicinal chemistry (01.07.2010)
Published in European journal of medicinal chemistry (01.07.2010)
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Journal Article
Optimized N-phenyl- N′-(2-chloroethyl)ureas as potential antineoplastic agents: Synthesis and growth inhibition activity
Moreau, Emmanuel, Fortin, Sébastien, Desjardins, Michel, Rousseau, Jean L.C., Petitclerc, Éric, C.-Gaudreault, René
Published in Bioorganic & medicinal chemistry (15.12.2005)
Published in Bioorganic & medicinal chemistry (15.12.2005)
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New soft alkylating agents with enhanced cytotoxicity against cancer cells resistant to chemotherapeutics and hypoxia
PATENAUDE, Alexandre, DESCHESNES, Réna G, ROUSSEAU, Jean L. C, PETITCLERC, Eric, LACROIX, Jacques, COTE, Marie-France, GAUDREAULT, René C
Published in Cancer research (Chicago, Ill.) (01.03.2007)
Published in Cancer research (Chicago, Ill.) (01.03.2007)
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