Distinct Responses to Menin Inhibition and Synergy with DOT1L Inhibition in KMT2A -Rearranged Acute Lymphoblastic and Myeloid Leukemia
Adriaanse, Fabienne R S, Schneider, Pauline, Arentsen-Peters, Susan T C J M, Fonseca, Ana M Neves da, Stutterheim, Janine, Pieters, Rob, Zwaan, C Michel, Stam, Ronald W
Published in International journal of molecular sciences (01.06.2024)
Published in International journal of molecular sciences (01.06.2024)
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Sensitive GATA1 mutation screening reliably identifies neonates with Down syndrome at risk for myeloid leukemia
Goemans, Bianca F., Noort, Sanne, Blink, Marjolein, Wang, Yong-Dong, Peters, Susan T. C. J., van Wouwe, Jacobus P., Kaspers, Gertjan, de Haas, Valerie, Kollen, Wouter J., van der Velden, Vincent H. J., Gruber, Tanja A., Zwaan, Christian M.
Published in Leukemia (01.08.2021)
Published in Leukemia (01.08.2021)
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CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in KMT2A-Rearranged Acute Lymphoblastic Leukemia
Schneider, Pauline, Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M., Vrenken, Kirsten S., Rockx-Brouwer, Dedeke, Adriaanse, Fabienne R. S., Hoeve, Veerle, Paassen, Irene, Drost, Jarno, Pieters, Rob, Stam, Ronald W.
Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
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Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia
Verbeek, Tamara C. A. I., Vrenken, Kirsten S., Arentsen-Peters, Susan T. C. J. M., Castro, Patricia Garrido, van de Ven, Marieke, van Tellingen, Olaf, Pieters, Rob, Stam, Ronald W.
Published in Communications biology (04.10.2024)
Published in Communications biology (04.10.2024)
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Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia
Hollink, Iris H.I.M., van den Heuvel-Eibrink, Marry M., Zimmermann, Martin, Balgobind, Brian V., Arentsen-Peters, Susan T.C.J.M., Alders, Marielle, Willasch, Andre, Kaspers, Gertjan J.L., Trka, Jan, Baruchel, Andre, de Graaf, Siebold S.N., Creutzig, Ursula, Pieters, Rob, Reinhardt, Dirk, Zwaan, C. Michel
Published in Blood (04.06.2009)
Published in Blood (04.06.2009)
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NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern
Hollink, Iris H.I.M., van den Heuvel-Eibrink, Marry M., Arentsen-Peters, Susan T.C.J.M., Pratcorona, Marta, Abbas, Saman, Kuipers, Jenny E., van Galen, Janneke F., Beverloo, H. Berna, Sonneveld, Edwin, Kaspers, Gert-Jan J.L., Trka, Jan, Baruchel, Andre, Zimmermann, Martin, Creutzig, Ursula, Reinhardt, Dirk, Pieters, Rob, Valk, Peter J.M., Zwaan, C. Michel
Published in Blood (29.09.2011)
Published in Blood (29.09.2011)
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CBL mutations do not frequently occur in paediatric acute myeloid leukaemia
Coenen, Eva A., Driessen, Emma M. C., Zwaan, C.Michel, Stary, Jan, Baruchel, Andre, de Haas, Valerie, de Bont, Eveline S. J. M., Reinhardt, Dirk, Kaspers, Gertjan J. L., Arentsen-Peters, Susan T. C. J. M., Meyer, Claus, Marschalek, Rolf, Pieters, Rob, Stam, Ronald W., van den Heuvel-Eibrink, Marry M.
Published in British journal of haematology (01.12.2012)
Published in British journal of haematology (01.12.2012)
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High-Throughput Drug Library Screening in Primary KMT2A -Rearranged Infant ALL Cells Favors the Identification of Drug Candidates That Activate P53 Signaling
Wander, Priscilla, Arentsen-Peters, Susan T C J M, Vrenken, Kirsten S, Pinhanҫos, Sandra Mimoso, Koopmans, Bianca, Dolman, M Emmy M, Jones, Luke, Garrido Castro, Patricia, Schneider, Pauline, Kerstjens, Mark, Molenaar, Jan J, Pieters, Rob, Zwaan, Christian Michel, Stam, Ronald W
Published in Biomedicines (10.03.2022)
Published in Biomedicines (10.03.2022)
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Somatic thrombopoietin (THPO) gene mutations in childhood myeloid leukemias
Houwing, Maite E., Koopman-Coenen, Eva A., Kersseboom, Rogier, Gooskens, Saskia, Appel, Inge M., Arentsen-Peters, Susan T. C. J. M., de Vries, Andrica C. H., Reinhardt, Dirk, Stary, Jan, Baruchel, André, de Haas, Valerie, Blink, Marjolein, Lopes Cardozo, Rob H., Pieters, Rob, Michel Zwaan, C., van den Heuvel-Eibrink, Marry M.
Published in International journal of hematology (01.07.2015)
Published in International journal of hematology (01.07.2015)
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A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study
Den Boer, Monique L, Dr, van Slegtenhorst, Marjon, PhD, De Menezes, Renée X, PhD, Cheok, Meyling H, PhD, Buijs-Gladdines, Jessica GCAM, BSc, Peters, Susan TCJM, BSc, Van Zutven, Laura JCM, PhD, Beverloo, H Berna, PhD, Van der Spek, Peter J, Prof, Escherich, Gaby, PhD, Horstmann, Martin A, Prof, Janka-Schaub, Gritta E, Prof, Kamps, Willem A, Prof, Evans, William E, Prof, Pieters, Rob, Prof
Published in The lancet oncology (01.02.2009)
Published in The lancet oncology (01.02.2009)
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Acute myeloid leukaemia in a case with Tatton-Brown-Rahman syndrome: the peculiar DNMT3A R882 mutation
Hollink, Iris H I M, van den Ouweland, Ans M W, Beverloo, H Berna, Arentsen-Peters, Susan T C J M, Zwaan, C Michel, Wagner, Anja
Published in Journal of medical genetics (01.12.2017)
Published in Journal of medical genetics (01.12.2017)
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Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia
Wander, Priscilla, Cheung, Laurence C., Pinhanҫos, Sandra S., Jones, Luke, Kerstjens, Mark, Arentsen-Peters, Susan T.C.J.M., Singh, Sajla, Chua, Grace-Alyssa, Castro, Patricia Garrido, Schneider, Pauline, Dolman, M. Emmy M., Koopmans, Bianca, Molenaar, Jan J., Pieters, Rob, Zwaan, C. Michel, Kotecha, Rishi S., Stam, Ronald W.
Published in Leukemia (01.11.2020)
Published in Leukemia (01.11.2020)
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Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia
BALGOBIND, Brian V, HOLLINK, Iris H. I. M, ZEMANOVA, Zuzana, STARY, Jan, CAYUELA, Jean-Michel, BARUCHEL, Andre, CREUTZIG, Ursula, REINHARDT, Dirk, PIETERS, Rob, MICHEL ZWAAN, C, VAN DEN HEUVEL-EIBRINK, Marry M, ARENTSEN-PETERS, Susan T. C. J. M, ZIMMERMANN, Martin, HARBOTT, Jochen, BERNA BEVERLOO, H, VON BERGH, Anne R. M, CLOOS, Jacqueline, KASPERS, Gertjan J. L, DE HAAS, Valerie
Published in Haematologica (Roma) (01.10.2011)
Published in Haematologica (Roma) (01.10.2011)
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Modelling acquired resistance to DOT1L inhibition exhibits the adaptive potential of KMT2A-rearranged acute lymphoblastic leukemia
Schneider, Pauline, Crump, Nicholas T, Arentsen-Peters, Susan T C J M, Smith, Alastair L, Hagelaar, Rico, Adriaanse, Fabienne R S, Bos, Romy S, de Jong, Anja, Nierkens, Stefan, Koopmans, Bianca, Milne, Thomas A, Pieters, Rob, Stam, Ronald W
Published in Experimental hematology & oncology (22.09.2023)
Published in Experimental hematology & oncology (22.09.2023)
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High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia
Wander, Priscilla, Arentsen-Peters, Susan T.C.J.M., Pinhanҫos, Sandra S., Koopmans, Bianca, Dolman, M.Emmy M., Ariese, Rijndert, Bos, Frank L., Castro, Patricia Garrido, Jones, Luke, Schneider, Pauline, Navarro, Miriam Guillen, Molenaar, Jan J., Rios, Anne C., Zwaan, C. Michel, Stam, Ronald W.
Published in Translational oncology (01.05.2021)
Published in Translational oncology (01.05.2021)
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Harnessing Gene Expression Profiles for the Identification of Ex Vivo Drug Response Genes in Pediatric Acute Myeloid Leukemia
Cucchi, David G J, Bachas, Costa, van den Heuvel-Eibrink, Marry M, Arentsen-Peters, Susan T C J M, Kwidama, Zinia J, Schuurhuis, Gerrit J, Assaraf, Yehuda G, de Haas, Valérie, Kaspers, Gertjan J L, Cloos, Jacqueline
Published in Cancers (15.05.2020)
Published in Cancers (15.05.2020)
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BCOR and BCORL1 mutations in pediatric acute myeloid leukemia
de Rooij, Jasmijn D E, van den Heuvel-Eibrink, Marry M, Hermkens, Malou C H, Verboon, Lonneke J, Arentsen-Peters, Susan T C J M, Fornerod, Maarten, Baruchel, Andre, Stary, Jan, Reinhardt, Dirk, de Haas, Valerie, Pieters, Rob, Zwaan, C Michel
Published in Haematologica (Roma) (01.05.2015)
Published in Haematologica (Roma) (01.05.2015)
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No prognostic impact of the WT1 gene single nucleotide polymorphism rs16754 in pediatric acute myeloid leukemia
Hollink, Iris H I M, van den Heuvel-Eibrink, Marry M, Zimmermann, Martin, Balgobind, Brian V, Arentsen-Peters, Susan T C J M, Alders, Marielle, Willasch, Andre, Kaspers, Gert-Jan J L, Trka, Jan, Baruchel, Andre, Creutzig, Ursula, Pieters, Rob, Reinhardt, Dirk, Zwaan, C Michel
Published in Journal of clinical oncology (01.10.2010)
Published in Journal of clinical oncology (01.10.2010)
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CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in IKMT2A/I-Rearranged Acute Lymphoblastic Leukemia
Schneider, Pauline, Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M, Vrenken, Kirsten S, Rockx-Brouwer, Dedeke, Adriaanse, Fabienne R. S, Hoeve, Veerle, Paassen, Irene, Drost, Jarno, Pieters, Rob, Stam, Ronald W
Published in International journal of molecular sciences (01.08.2023)
Published in International journal of molecular sciences (01.08.2023)
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Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia
BALGOBIND, Brian V, VAN DEN HEUVEL-EIBRINK, Marry M, CAYUELA, Jean-Michel, BARUCHEL, Andre, MEYER, Claus, MARSCHALEK, Rolf, TRKA, Jan, STARY, Jan, BERNA BEVERLOO, H, PIETERS, Rob, ZWAAN, C. Michel, DEN BOER, Monique L, DE MENEZES, Renee X, REINHARDT, Dirk, HOLLINK, Iris H. I. M, ARENTSEN-PETERS, Susan T. J. C. M, VAN WERING, Elisabeth R, KASPERS, Gertjan J. L, CLOOS, Jacqueline, DE BONT, Evelien S. J. M
Published in Haematologica (Roma) (01.02.2011)
Published in Haematologica (Roma) (01.02.2011)
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