Artificial neural networks enable genome-scale simulations of intracellular signaling
Nilsson, Avlant, Peters, Joshua M., Meimetis, Nikolaos, Bryson, Bryan, Lauffenburger, Douglas A.
Published in Nature communications (02.06.2022)
Published in Nature communications (02.06.2022)
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Journal Article
CD8+ T cell priming that is required for curative intratumorally anchored anti-4-1BB immunotherapy is constrained by Tregs
Palmeri, Joseph R., Lax, Brianna M., Peters, Joshua M., Duhamel, Lauren, Stinson, Jordan A., Santollani, Luciano, Lutz, Emi A., Pinney, William, Bryson, Bryan D., Dane Wittrup, K.
Published in Nature communications (01.03.2024)
Published in Nature communications (01.03.2024)
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Journal Article
TLR2 is non-redundant in the population and subpopulation responses to Mycobacterium tuberculosis in macrophages and in vivo
Jani, Charul, Solomon, Sydney L, Peters, Joshua M, Pringle, Stephanie C, Hinman, Amelia E, Boucau, Julie, Bryson, Bryan D, Barczak, Amy K
Published in mSystems (31.08.2023)
Published in mSystems (31.08.2023)
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Journal Article
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control
Gideon, Hannah P., Hughes, Travis K., Tzouanas, Constantine N., Wadsworth, Marc H., Tu, Ang Andy, Gierahn, Todd M., Peters, Joshua M., Hopkins, Forrest F., Wei, Jun-Rong, Kummerlowe, Conner, Grant, Nicole L., Nargan, Kievershen, Phuah, Jia Yao, Borish, H. Jacob, Maiello, Pauline, White, Alexander G., Winchell, Caylin G., Nyquist, Sarah K., Ganchua, Sharie Keanne C., Myers, Amy, Patel, Kush V., Ameel, Cassaundra L., Cochran, Catherine T., Ibrahim, Samira, Tomko, Jaime A., Frye, Lonnie James, Rosenberg, Jacob M., Shih, Angela, Chao, Michael, Klein, Edwin, Scanga, Charles A., Ordovas-Montanes, Jose, Berger, Bonnie, Mattila, Joshua T., Madansein, Rajhmun, Love, J. Christopher, Lin, Philana Ling, Leslie, Alasdair, Behar, Samuel M., Bryson, Bryan, Flynn, JoAnne L., Fortune, Sarah M., Shalek, Alex K.
Published in Immunity (Cambridge, Mass.) (10.05.2022)
Published in Immunity (Cambridge, Mass.) (10.05.2022)
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Journal Article
Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis
Kotov, Dmitri I., Lee, Ophelia V., Fattinger, Stefan A., Langner, Charlotte A., Guillen, Jaresley V., Peters, Joshua M., Moon, Andres, Burd, Eileen M., Witt, Kristen C., Stetson, Daniel B., Jaye, David L., Bryson, Bryan D., Vance, Russell E.
Published in Cell (07.12.2023)
Published in Cell (07.12.2023)
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Journal Article
Scalable, compressed phenotypic screening using pooled perturbations
Liu, Nuo, Kattan, Walaa E, Mead, Benjamin E, Kummerlowe, Conner, Cheng, Thomas, Ingabire, Sarah, Cheah, Jaime H, Soule, Christian K, Vrcic, Anita, McIninch, Jane K, Triana, Sergio, Guzman, Manuel, Dao, Tyler T, Peters, Joshua M, Lowder, Kristen E, Crawford, Lorin, Amini, Ava P, Blainey, Paul C, Hahn, William C, Cleary, Brian, Bryson, Bryan, Winter, Peter S, Raghavan, Srivatsan, Shalek, Alex K
Published in Nature biotechnology (07.10.2024)
Published in Nature biotechnology (07.10.2024)
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Journal Article
Fc-engineered antibodies promote neutrophil-dependent control of Mycobacterium tuberculosis
Irvine, Edward B., Nikolov, Angel, Khan, Mehak Z., Peters, Joshua M., Lu, Richard, Sixsmith, Jaimie, Wallace, Aaron, van Woudenbergh, Esther, Shin, Sally, Karpinski, Wiktor, Hsiao, Jeff C., Casadevall, Arturo, Bryson, Bryan D., Cavacini, Lisa, Grace, Patricia S., Alter, Galit, Fortune, Sarah M.
Published in Nature microbiology (01.09.2024)
Published in Nature microbiology (01.09.2024)
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Journal Article
JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia
Rosenberg, Jacob M., Peters, Joshua M., Hughes, Travis, Lareau, Caleb A., Ludwig, Leif S., Massoth, Lucas R., Austin-Tse, Christina, Rehm, Heidi L., Bryson, Bryan, Chen, Yi-Bin, Regev, Aviv, Shalek, Alex K., Fortune, Sarah M., Sykes, David B.
Published in Med (New York, N.Y. : Online) (14.01.2022)
Published in Med (New York, N.Y. : Online) (14.01.2022)
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Journal Article
Antibody-Fab and -Fc features promote Mycobacterium tuberculosis restriction
Grace, Patricia S, Peters, Joshua M, Sixsmith, Jaimie, Lu, Richard, Luedeman, Corinne, Fenderson, Brooke A, Vickers, Andrew, Slein, Matthew D, Irvine, Edward B, McKitrick, Tanya, Wei, Mo-Hui, Cummings, Richard D, Wallace, Aaron, Cavacini, Lisa A, Choudhary, Alok, Proulx, Megan K, Sundling, Christopher, Källenius, Gunilla, Reljic, Rajko, Ernst, Joel D, Casadevall, Arturo, Locht, Camille, Pinter, Abraham, Sasseti, Christopher M, Bryson, Bryan D, Fortune, Sarah M, Alter, Galit
Published in bioRxiv (11.10.2024)
Published in bioRxiv (11.10.2024)
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Journal Article
Tregs constrain CD8+ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy
Palmeri, Joseph R, Lax, Brianna M, Peters, Joshua M, Duhamel, Lauren R, Stinson, Jordan A, Santollani, Luciano, Lutz, Emi A, Pinney, William, Bryson, Bryan D, Karl Dane Wittrup
Published in bioRxiv (01.02.2023)
Published in bioRxiv (01.02.2023)
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Tregs constrain CD8 + T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy
Palmeri, Joseph R, Lax, Brianna M, Peters, Joshua M, Duhamel, Lauren, Stinson, Jordan A, Santollani, Luciano, Lutz, Emi A, Pinney, 3rd, William, Bryson, Bryan D, Wittrup, K Dane
Published in bioRxiv : the preprint server for biology (01.02.2023)
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Published in bioRxiv : the preprint server for biology (01.02.2023)
Journal Article
Protective intravenous BCG vaccination induces enhanced immune signaling in the airways
Peters, Joshua M, Irvine, Edward B, Rosenberg, Jacob M, Wadsworth, Marc H, Hughes, Travis K, Sutton, Matthew, Nyquist, Sarah K, Bromley, Joshua D, Mondal, Rajib, Roederer, Mario, Seder, Robert A, Darrah, Patricia A, Alter, Galit, Flynn, JoAnne L, Shalek, Alex K, Fortune, Sarah M, Bryson, Bryan D
Published in bioRxiv (18.07.2023)
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Published in bioRxiv (18.07.2023)
Journal Article
Cellular sources and targets of type I interferons that drive susceptibility to tuberculosis
Kotov, Dmitri I, Lee, Ophelia V, Langner, Charlotte, Guillen, Jaresley V, Peters, Joshua M, Moon, Andres, Burd, Eileen M, Witt, Kristen C, Stetson, Daniel B, Jaye, David L, Bryson, Bryan D, Vance, Russell E
Published in bioRxiv (18.10.2022)
Published in bioRxiv (18.10.2022)
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