Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors
Gjorgjieva, Marina, Tomašič, Tihomir, Barančokova, Michaela, Katsamakas, Sotirios, Ilaš, Janez, Tammela, Päivi, Peterlin Mašič, Lucija, Kikelj, Danijel
Published in Journal of medicinal chemistry (13.10.2016)
Published in Journal of medicinal chemistry (13.10.2016)
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Overcoming challenges of HERG potassium channel liability through rational design: Eag1 inhibitors for cancer treatment
Toplak, Žan, Hendrickx, Louise A., Abdelaziz, Reham, Shi, Xiaoyi, Peigneur, Steve, Tomašič, Tihomir, Tytgat, Jan, Peterlin‐Mašič, Lucija, Pardo, Luis A.
Published in Medicinal research reviews (01.01.2022)
Published in Medicinal research reviews (01.01.2022)
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Discovery of 4,5,6,7-Tetrahydrobenzo[1,2‑d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site
Tomašič, Tihomir, Katsamakas, Sotirios, Hodnik, Žiga, Ilaš, Janez, Brvar, Matjaž, Solmajer, Tom, Montalvão, Sofia, Tammela, Päivi, Banjanac, Mihailo, Ergović, Gabrijela, Anderluh, Marko, Mašič, Lucija Peterlin, Kikelj, Danijel
Published in Journal of medicinal chemistry (23.07.2015)
Published in Journal of medicinal chemistry (23.07.2015)
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ATP-competitive DNA gyrase and topoisomerase IV inhibitors as antibacterial agents
Durcik, Martina, Tomašič, Tihomir, Zidar, Nace, Zega, Anamarija, Kikelj, Danijel, Mašič, Lucija Peterlin, Ilaš, Janez
Published in Expert opinion on therapeutic patents (04.03.2019)
Published in Expert opinion on therapeutic patents (04.03.2019)
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Computer-aided structure-based optimization of 4,5,6,7-tetrahydrobenzo[]thiazole-2,6-diamine derivatives as DNA gyrase B inhibitors
Gutierrez, Lucas J, Vettorazzi, Marcela, Dernovšek, Jaka, Durcik, Martina, Maši, Lucija Peterlin, Tomaši, Tihomir, Enriz, Ricardo D
Published in New journal of chemistry (20.02.2023)
Published in New journal of chemistry (20.02.2023)
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Rational design of balanced dual-targeting antibiotics with limited resistance
Nyerges, Akos, Tomašič, Tihomir, Durcik, Martina, Revesz, Tamas, Szili, Petra, Draskovits, Gabor, Bogar, Ferenc, Skok, Žiga, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Kikelj, Danijel, Daruka, Lejla, Kintses, Balint, Vasarhelyi, Balint, Foldesi, Imre, Kata, Diána, Welin, Martin, Kimbung, Raymond, Focht, Dorota, Mašič, Lucija Peterlin, Pal, Csaba
Published in PLoS biology (05.10.2020)
Published in PLoS biology (05.10.2020)
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Benzothiazole DNA gyrase inhibitors and their conjugates with siderophore mimics: design, synthesis and evaluation
Durcik, Martina, Cruz, Cristina D, Scorciapino, Mariano Andrea, Ilaš, Janez, Tammela, Päivi, Ceccarelli, Matteo, Maši, Lucija Peterlin, Tomaši, Tihomir
Published in RSC advances (17.01.2024)
Published in RSC advances (17.01.2024)
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N‑Phenyl-4,5-dibromopyrrolamides and N‑Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation
Zidar, Nace, Macut, Helena, Tomašič, Tihomir, Brvar, Matjaž, Montalvão, Sofia, Tammela, Päivi, Solmajer, Tom, Peterlin Mašič, Lucija, Ilaš, Janez, Kikelj, Danijel
Published in Journal of medicinal chemistry (13.08.2015)
Published in Journal of medicinal chemistry (13.08.2015)
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New N -phenylpyrrolamide inhibitors of DNA gyrase with improved antibacterial activity
Cotman, Andrej Emanuel, Fulgheri, Federica, Piga, Martina, Peršolja, Peter, Tiz, Davide Benedetto, Skok, Žiga, Durcik, Martina, Sterle, Maša, Dernovšek, Jaka, Cruz, Cristina D, Tammela, Päivi, Szili, Petra Éva, Daruka, Lejla, Pál, Csaba, Zega, Anamarija, Mašič, Lucija Peterlin, Ilaš, Janez, Tomašič, Tihomir, Kikelj, Danijel, Zidar, Nace
Published in RSC advances (04.09.2024)
Published in RSC advances (04.09.2024)
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Bioactivation of bisphenol A and its analogs (BPF, BPAF, BPZ and DMBPA) in human liver microsomes
Schmidt, Jan, Kotnik, Petra, Trontelj, Jurij, Knez, Željko, Mašič, Lucija Peterlin
Published in Toxicology in vitro (01.06.2013)
Published in Toxicology in vitro (01.06.2013)
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Discovery of Novel 5-Benzylidenerhodanine and 5-Benzylidenethiazolidine-2,4-dione Inhibitors of MurD Ligase
Zidar, Nace, Tomašić, Tihomir, Šink, Roman, Rupnik, Veronika, Kovač, Andreja, Turk, Samo, Patin, Delphine, Blanot, Didier, Contreras Martel, Carlos, Dessen, Andréa, Müller Premru, Manica, Zega, Anamarija, Gobec, Stanislav, Peterlin Mašič, Lucija, Kikelj, Danijel
Published in Journal of medicinal chemistry (23.09.2010)
Published in Journal of medicinal chemistry (23.09.2010)
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Synthesis, Antiproliferative Effect, and Topoisomerase II Inhibitory Activity of 3‑Methyl-2-phenyl‑1H‑indoles
Zidar, Nace, Secci, Daniela, Tomašič, Tihomir, Mašič, Lucija Peterlin, Kikelj, Danijel, Passarella, Daniele, Argaez, Aida Nelly Garcia, Hyeraci, Mariafrancesca, Dalla Via, Lisa
Published in ACS medicinal chemistry letters (14.05.2020)
Published in ACS medicinal chemistry letters (14.05.2020)
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Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors
Dernovšek, Jaka, Zajec, Živa, Durcik, Martina, Mašič, Lucija Peterlin, Gobec, Martina, Zidar, Nace, Tomašič, Tihomir
Published in Pharmaceutics (17.08.2021)
Published in Pharmaceutics (17.08.2021)
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Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors
Skok, Žiga, Barančoková, Michaela, Benek, Ondřej, Cruz, Cristina Durante, Tammela, Päivi, Tomašič, Tihomir, Zidar, Nace, Mašič, Lucija Peterlin, Zega, Anamarija, Stevenson, Clare E. M, Mundy, Julia E. A, Lawson, David M, Maxwell, Anthony, Kikelj, Danijel, Ilaš, Janez
Published in ACS medicinal chemistry letters (10.12.2020)
Published in ACS medicinal chemistry letters (10.12.2020)
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Structure-Function Studies of Sponge-Derived Compounds on the Cardiac CaV3.1 Channel
Depuydt, Anne-Sophie, Patel, Piyush A., Toplak, Žan, Bhat, Chinmaya, Voráčová, Manuela, Eteläinen, Irene, Vitulano, Fiammetta, Bruun, Tanja, Lempinen, Antti, Hribernik, Nives, Mäki-Lohiluoma, Eero, Hendrickx, Louise, Pinheiro-Junior, Ernesto Lopes, Tomašič, Tihomir, Mašič, Lucija Peterlin, Yli-Kauhaluoma, Jari, Kiuru, Paula, Tytgat, Jan, Peigneur, Steve
Published in International journal of molecular sciences (08.02.2023)
Published in International journal of molecular sciences (08.02.2023)
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Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity
Gubič, Špela, Hendrickx, Louise, Shi, Xiaoyi, Toplak, Žan, Možina, Štefan, Theemsche, Kenny, Pinheiro-Junior, Ernesto, Peigneur, Steve, Labro, Alain, Pardo, Luis, Tytgat, Jan, Tomašič, Tihomir, Mašič, Lucija
Published in Cancers (24.05.2022)
Published in Cancers (24.05.2022)
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Efficient Synthesis of Hydroxy-Substituted 2‑Aminobenzo[d]thiazole-6-carboxylic Acid Derivatives as New Building Blocks in Drug Discovery
Durcik, Martina, Toplak, Žan, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Kikelj, Danijel, Mašič, Lucija Peterlin, Tomašič, Tihomir
Published in ACS omega (14.04.2020)
Published in ACS omega (14.04.2020)
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5-Benzylidenethiazolidin-4-ones as Multitarget Inhibitors of Bacterial Mur Ligases
Tomašić, Tihomir, Zidar, Nace, Kovač, Andreja, Turk, Samo, Simčič, Mihael, Blanot, Didier, Müller-Premru, Manica, Filipič, Metka, Grdadolnik, Simona Golič, Zega, Anamarija, Anderluh, Marko, Gobec, Stanislav, Kikelj, Danijel, Peterlin Mašič, Lucija
Published in ChemMedChem (01.02.2010)
Published in ChemMedChem (01.02.2010)
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Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues
Zidar, Nace, Montalvão, Sofia, Hodnik, Žiga, Nawrot, Dorota A, Žula, Aleš, Ilaš, Janez, Kikelj, Danijel, Tammela, Päivi, Mašič, Lucija Peterlin
Published in Marine drugs (14.02.2014)
Published in Marine drugs (14.02.2014)
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New Diarylamine KV10.1 Inhibitors and Their Anticancer Potential
Gubič, Špela, Toplak, Žan, Shi, Xiaoyi, Dernovšek, Jaka, Hendrickx, Louise Antonia, Pinheiro-Junior, Ernesto Lopes, Peigneur, Steve, Tytgat, Jan, Pardo, Luis A., Peterlin Mašič, Lucija, Tomašič, Tihomir
Published in Pharmaceutics (17.09.2022)
Published in Pharmaceutics (17.09.2022)
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