The role of thyroglobulin in thyroid hormonogenesis
Citterio, Cintia E., Targovnik, Héctor M., Arvan, Peter
Published in Nature reviews. Endocrinology (01.06.2019)
Published in Nature reviews. Endocrinology (01.06.2019)
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Pathological β-Cell Endoplasmic Reticulum Stress in Type 2 Diabetes: Current Evidence
Shrestha, Neha, De Franco, Elisa, Arvan, Peter, Cnop, Miriam
Published in Frontiers in endocrinology (Lausanne) (22.04.2021)
Published in Frontiers in endocrinology (Lausanne) (22.04.2021)
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Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates
Cunningham, Corey N., Williams, Jeffrey M., Knupp, Jeffrey, Arunagiri, Anoop, Arvan, Peter, Tsai, Billy
Published in Molecular cell (08.08.2019)
Published in Molecular cell (08.08.2019)
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Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes
Sun, Jinhong, Cui, Jingqiu, He, Qing, Chen, Zheng, Arvan, Peter, Liu, Ming
Published in Molecular aspects of medicine (01.04.2015)
Published in Molecular aspects of medicine (01.04.2015)
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Biosynthesis, structure, and folding of the insulin precursor protein
Liu, Ming, Weiss, Michael A., Arunagiri, Anoop, Yong, Jing, Rege, Nischay, Sun, Jinhong, Haataja, Leena, Kaufman, Randal J., Arvan, Peter
Published in Diabetes, obesity & metabolism (01.09.2018)
Published in Diabetes, obesity & metabolism (01.09.2018)
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Journal Article
PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones
Chen, Yu-Jie, Knupp, Jeffrey, Arunagiri, Anoop, Haataja, Leena, Arvan, Peter, Tsai, Billy
Published in Nature communications (13.10.2021)
Published in Nature communications (13.10.2021)
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Journal Article
Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes
Arunagiri, Anoop, Haataja, Leena, Cunningham, Corey N., Shrestha, Neha, Tsai, Billy, Qi, Ling, Liu, Ming, Arvan, Peter
Published in Annals of the New York Academy of Sciences (01.04.2018)
Published in Annals of the New York Academy of Sciences (01.04.2018)
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Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes
Fang, Zhou, Weng, Chen, Li, Haiyan, Tao, Ran, Mai, Weihua, Liu, Xiaoxiao, Lu, Leina, Lai, Sisi, Duan, Qing, Alvarez, Carlos, Arvan, Peter, Wynshaw-Boris, Anthony, Li, Yun, Pei, Yanxin, Jin, Fulai, Li, Yan
Published in Cell reports (Cambridge) (12.03.2019)
Published in Cell reports (Cambridge) (12.03.2019)
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Journal Article
Integration of ER protein quality control mechanisms defines β cell function and ER architecture
Shrestha, Neha, Torres, Mauricio, Zhang, Jason, Lu, You, Haataja, Leena, Reinert, Rachel B, Knupp, Jeffrey, Chen, Yu-Jie, Parlakgul, Gunes, Arruda, Ana Paula, Tsai, Billy, Arvan, Peter, Qi, Ling
Published in The Journal of clinical investigation (03.01.2023)
Published in The Journal of clinical investigation (03.01.2023)
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Journal Article
Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum
Haataja, Leena, Manickam, Nandini, Soliman, Ann, Tsai, Billy, Liu, Ming, Arvan, Peter
Published in Diabetes (New York, N.Y.) (01.04.2016)
Published in Diabetes (New York, N.Y.) (01.04.2016)
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Journal Article
ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis
Shi, Guojun, Somlo, Diane RM, Kim, Geun Hyang, Prescianotto-Baschong, Cristina, Sun, Shengyi, Beuret, Nicole, Long, Qiaoming, Rutishauser, Jonas, Arvan, Peter, Spiess, Martin, Qi, Ling
Published in The Journal of clinical investigation (01.10.2017)
Published in The Journal of clinical investigation (01.10.2017)
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Journal Article
Proinsulin misfolding is an early event in the progression to type 2 diabetes
Arunagiri, Anoop, Haataja, Leena, Pottekat, Anita, Pamenan, Fawnnie, Kim, Soohyun, Zeltser, Lori M, Paton, Adrienne W, Paton, James C, Tsai, Billy, Itkin-Ansari, Pamela, Kaufman, Randal J, Liu, Ming, Arvan, Peter
Published in eLife (11.06.2019)
Published in eLife (11.06.2019)
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Journal Article
How Does Type 1 Diabetes Develop?: The Notion of Homicide or β-Cell Suicide Revisited
ATKINSON, Mark A, BLUESTONE, Jeffrey A, RHODES, Christopher J, EISENBARTH, George S, HEBROK, Matthias, HEROLD, Kevan C, ACCILI, Domenico, PIETROPAOLO, Massimo, ARVAN, Peter R, VON HERRATH, Matthias, MARKEL, Dorene S
Published in Diabetes (New York, N.Y.) (01.05.2011)
Published in Diabetes (New York, N.Y.) (01.05.2011)
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Journal Article
Adaptation to chronic ER stress enforces pancreatic β-cell plasticity
Chen, Chien-Wen, Guan, Bo-Jhih, Alzahrani, Mohammed R., Gao, Zhaofeng, Gao, Long, Bracey, Syrena, Wu, Jing, Mbow, Cheikh A., Jobava, Raul, Haataja, Leena, Zalavadia, Ajay H., Schaffer, Ashleigh E., Lee, Hugo, LaFramboise, Thomas, Bederman, Ilya, Arvan, Peter, Mathews, Clayton E., Gerling, Ivan C., Kaestner, Klaus H., Tirosh, Boaz, Engin, Feyza, Hatzoglou, Maria
Published in Nature communications (08.08.2022)
Published in Nature communications (08.08.2022)
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Journal Article
Discovery of a Redox Thiol Switch: Implications for Cellular Energy Metabolism
Gao, Xing-Huang, Li, Ling, Parisien, Marc, Wu, Jing, Bederman, Ilya, Gao, Zhaofeng, Krokowski, Dawid, Chirieleison, Steven M., Abbott, Derek, Wang, Benlian, Arvan, Peter, Cameron, Mark, Chance, Mark, Willard, Belinda, Hatzoglou, Maria
Published in Molecular & cellular proteomics (01.05.2020)
Published in Molecular & cellular proteomics (01.05.2020)
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Journal Article
PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity
Jang, Insook, Pottekat, Anita, Poothong, Juthakorn, Yong, Jing, Lagunas-Acosta, Jacqueline, Charbono, Adriana, Chen, Zhouji, Scheuner, Donalyn L, Liu, Ming, Itkin-Ansari, Pamela, Arvan, Peter, Kaufman, Randal J
Published in eLife (11.06.2019)
Published in eLife (11.06.2019)
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Journal Article
Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling
Ghiasi, Seyed Mojtaba, Dahlby, Tina, Hede Andersen, Caroline, Haataja, Leena, Petersen, Sólrun, Omar-Hmeadi, Muhmmad, Yang, Mingyu, Pihl, Celina, Bresson, Sophie Emilie, Khilji, Muhammad Saad, Klindt, Kristian, Cheta, Oana, Perone, Marcelo J, Tyrberg, Björn, Prats, Clara, Barg, Sebastian, Tengholm, Anders, Arvan, Peter, Mandrup-Poulsen, Thomas, Marzec, Michal Tomasz
Published in Diabetes (New York, N.Y.) (01.04.2019)
Published in Diabetes (New York, N.Y.) (01.04.2019)
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Journal Article
Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response
Gao, Xing-Huang, Krokowski, Dawid, Guan, Bo-Jhih, Bederman, Ilya, Majumder, Mithu, Parisien, Marc, Diatchenko, Luda, Kabil, Omer, Willard, Belinda, Banerjee, Ruma, Wang, Benlian, Bebek, Gurkan, Evans, Charles R, Fox, Paul L, Gerson, Stanton L, Hoppel, Charles L, Liu, Ming, Arvan, Peter, Hatzoglou, Maria
Published in eLife (23.11.2015)
Published in eLife (23.11.2015)
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