Matching Mechanics and Energetics of Muscle Contraction Suggests Unconventional Chemomechanical Coupling during the Actin-Myosin Interaction
Pertici, Irene, Bongini, Lorenzo, Caremani, Marco, Reconditi, Massimo, Linari, Marco, Piazzesi, Gabriella, Lombardi, Vincenzo, Bianco, Pasquale
Published in International journal of molecular sciences (01.08.2023)
Published in International journal of molecular sciences (01.08.2023)
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Journal Article
Straightening Out the Elasticity of Myosin Cross-Bridges
Linari, Marco, Piazzesi, Gabriella, Pertici, Irene, Dantzig, Jody A., Goldman, Yale E., Lombardi, Vincenzo
Published in Biophysical journal (10.03.2020)
Published in Biophysical journal (10.03.2020)
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Journal Article
A myosin II nanomachine mimicking the striated muscle
Pertici, Irene, Bongini, Lorenzo, Melli, Luca, Bianchi, Giulio, Salvi, Luca, Falorsi, Giulia, Squarci, Caterina, Bozó, Tamás, Cojoc, Dan, Kellermayer, Miklós S. Z., Lombardi, Vincenzo, Bianco, Pasquale
Published in Nature communications (30.08.2018)
Published in Nature communications (30.08.2018)
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Journal Article
Orthophosphate increases the efficiency of slow muscle-myosin isoform in the presence of omecamtiv mecarbil
Governali, Serena, Caremani, Marco, Gallart, Cristina, Pertici, Irene, Stienen, Ger, Piazzesi, Gabriella, Ottenheijm, Coen, Lombardi, Vincenzo, Linari, Marco
Published in Nature communications (07.07.2020)
Published in Nature communications (07.07.2020)
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Journal Article
The force of the myosin motor sets cooperativity in thin filament activation of skeletal muscles
Caremani, Marco, Marcello, Matteo, Morotti, Ilaria, Pertici, Irene, Squarci, Caterina, Reconditi, Massimo, Bianco, Pasquale, Piazzesi, Gabriella, Lombardi, Vincenzo, Linari, Marco
Published in Communications biology (18.11.2022)
Published in Communications biology (18.11.2022)
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Journal Article
Force and kinetics of fast and slow muscle myosin determined with a synthetic sarcomere–like nanomachine
Buonfiglio, Valentina, Pertici, Irene, Marcello, Matteo, Morotti, Ilaria, Caremani, Marco, Reconditi, Massimo, Linari, Marco, Fanelli, Duccio, Lombardi, Vincenzo, Bianco, Pasquale
Published in Communications biology (23.03.2024)
Published in Communications biology (23.03.2024)
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Journal Article
Myopalladin promotes muscle growth through modulation of the serum response factor pathway
Filomena, Maria Carmela, Yamamoto, Daniel L., Caremani, Marco, Kadarla, Vinay K., Mastrototaro, Giuseppina, Serio, Simone, Vydyanath, Anupama, Mutarelli, Margherita, Garofalo, Arcamaria, Pertici, Irene, Knöll, Ralph, Nigro, Vincenzo, Luther, Pradeep K., Lieber, Richard L., Beck, Moriah R., Linari, Marco, Bang, Marie‐Louise
Published in Journal of cachexia, sarcopenia and muscle (01.02.2020)
Published in Journal of cachexia, sarcopenia and muscle (01.02.2020)
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Journal Article
Definition of the mechanokinetic parameters accounting for the functional diversity of slow and fast isoforms of skeletal muscle myosin with a synthetic nanomachine
Buonfiglio, Valentina, Pertici, Irene, Lombardi, Vincenzo, Fanelli, Duccio, Bianco, Pasquale
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
The synthetic nanomachine powered by bovine cardiac myosin demostrates that force and power of the atrial myosin isoform are less then those of the ventricular isoform
Pertici, Irene, Rivera, Christine, Nag, Suman, Lombardi, Vincenzo, Bianco, Pasquale
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Contracting striated muscle has a dynamic I‐band spring with an undamped stiffness 100 times larger than the passive stiffness
Powers, Joseph D., Bianco, Pasquale, Pertici, Irene, Reconditi, Massimo, Lombardi, Vincenzo, Piazzesi, Gabriella
Published in The Journal of physiology (01.01.2020)
Published in The Journal of physiology (01.01.2020)
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Journal Article
The performance of atrial and ventricular myosin isoforms purified from bovine heart and measured on a half-sarcomere like synthetic nanomachine
Pertici, Irene, Buonfiglio, Valentina, Rivera, Christine, Nag, Suman, Fanelli, Duccio, Lombardi, Vincenzo, Bianco, Pasquale
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
A mechanical model of the half-sarcomere which includes the contribution of titin
Pertici, Irene, Caremani, Marco, Reconditi, Massimo
Published in Journal of muscle research and cell motility (01.03.2019)
Published in Journal of muscle research and cell motility (01.03.2019)
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Journal Article
In Situ Characterization of the Working Stroke of the Slow and Fast Isoforms of Muscle Myosin
Caremani, Marco, Pertici, Irene, Percario, Valentina, Lombardi, Vincenzo, Linari, Marco
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
The mechanism of cooperativity in thin filament activation studied in demembranated fibers of slow skeletal muscle
Marcello, Matteo, Gallart, Cristina, Pertici, Irene, Reconditi, Massimo, Piazzesi, Gabriella, Lombardi, Vincenzo, Linari, Marco, Caremani, Marco
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
An integrated picture of the structural pathways controlling the heart performance
Morotti, Ilaria, Caremani, Marco, Marcello, Matteo, Pertici, Irene, Squarci, Caterina, Bianco, Pasquale, Narayanan, Theyencheri, Piazzesi, Gabriella, Reconditi, Massimo, Lombardi, Vincenzo, Linari, Marco
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (10.12.2024)
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Journal Article
Mechanical parameters of the molecular motor myosin II determined in permeabilised fibres from slow and fast skeletal muscles of the rabbit
Percario, Valentina, Boncompagni, Simona, Protasi, Feliciano, Pertici, Irene, Pinzauti, Francesca, Caremani, Marco
Published in The Journal of physiology (01.04.2018)
Published in The Journal of physiology (01.04.2018)
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Journal Article
Assessment of the cytoskeletal impact of beta-actin mutations leading to non-muscle actinopathies by means of dual laser optical tweezers (DLOT)
Battirossi, Elena, Niehaus, Indra, Prift, Kejsi, Pertici, Irene, Li Puma, Simone, Reconditi, Massimo, Lombardi, Vincenzo, Di Donato, Nataliya, Bianco, Pasquale
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article