PI3K inhibitors are finally coming of age
Vanhaesebroeck, Bart, Perry, Matthew W D, Brown, Jennifer R, André, Fabrice, Okkenhaug, Klaus
Published in Nature reviews. Drug discovery (01.10.2021)
Published in Nature reviews. Drug discovery (01.10.2021)
Get full text
Journal Article
14-3-3 modulation of the inflammatory response
Munier, Claire C., Ottmann, Christian, Perry, Matthew W.D.
Published in Pharmacological research (01.01.2021)
Published in Pharmacological research (01.01.2021)
Get full text
Journal Article
Design, Synthesis, and Biological Evaluation of MEK PROTACs
Vollmer, Stefan, Cunoosamy, Danen, Lv, Huafei, Feng, Huanxi, Li, Xia, Nan, Ziyang, Yang, Wenzhen, Perry, Matthew W. D
Published in Journal of medicinal chemistry (09.01.2020)
Published in Journal of medicinal chemistry (09.01.2020)
Get full text
Journal Article
A Radical Approach to Anionic Chemistry: Synthesis of Ketones, Alcohols, and Amines
Ni, Shengyang, Padial, Natalia M, Kingston, Cian, Vantourout, Julien C, Schmitt, Daniel C, Edwards, Jacob T, Kruszyk, Monika M, Merchant, Rohan R, Mykhailiuk, Pavel K, Sanchez, Brittany B, Yang, Shouliang, Perry, Matthew A, Gallego, Gary M, Mousseau, James J, Collins, Michael R, Cherney, Robert J, Lebed, Pavlo S, Chen, Jason S, Qin, Tian, Baran, Phil S
Published in Journal of the American Chemical Society (24.04.2019)
Published in Journal of the American Chemical Society (24.04.2019)
Get full text
Journal Article
Treatment of Carcinoma In Situ of the Glans Penis with Topical Chemotherapy Agents
Alnajjar, Hussain M, Lam, Wayne, Bolgeri, Marco, Rees, Rowland W, Perry, Matthew J.A, Watkin, Nicholas A
Published in European urology (01.11.2012)
Published in European urology (01.11.2012)
Get full text
Journal Article
hERG K(+) channels: structure, function, and clinical significance
Vandenberg, Jamie I, Perry, Matthew D, Perrin, Mark J, Mann, Stefan A, Ke, Ying, Hill, Adam P
Published in Physiological reviews (01.07.2012)
Published in Physiological reviews (01.07.2012)
Get full text
Journal Article
Structural and conformational determinants of macrocycle cell permeability
Over, Björn, Matsson, Pär, Tyrchan, Christian, Artursson, Per, Doak, Bradley C, Foley, Michael A, Hilgendorf, Constanze, Johnston, Stephen E, Lee, 4th, Maurice D, Lewis, Richard J, McCarren, Patrick, Muncipinto, Giovanni, Norinder, Ulf, Perry, Matthew W D, Duvall, Jeremy R, Kihlberg, Jan
Published in Nature chemical biology (01.12.2016)
Published in Nature chemical biology (01.12.2016)
Get full text
Journal Article
A class of highly selective inhibitors bind to an active state of PI3Kγ
Gangadhara, Gangadhara, Dahl, Göran, Bohnacker, Thomas, Rae, Rebecca, Gunnarsson, Jenny, Blaho, Stefan, Öster, Linda, Lindmark, Helena, Karabelas, Kostas, Pemberton, Nils, Tyrchan, Christian, Mogemark, Mickael, Wymann, Matthias P, Williams, Roger L, Perry, Matthew W D, Papavoine, Tineke, Petersen, Jens
Published in Nature chemical biology (01.04.2019)
Published in Nature chemical biology (01.04.2019)
Get full text
Journal Article
Author Correction: PI3K inhibitors are finally coming of age
Vanhaesebroeck, Bart, Perry, Matthew W D, Brown, Jennifer R, André, Fabrice, Okkenhaug, Klaus
Published in Nature reviews. Drug discovery (01.10.2021)
Published in Nature reviews. Drug discovery (01.10.2021)
Get full text
Journal Article
Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3‑Kinase (PI3K)‑γ Inhibitors
Pemberton, Nils, Mogemark, Mickael, Arlbrandt, Susanne, Bold, Peter, Cox, Rhona J, Gardelli, Cristina, Holden, Neil S, Karabelas, Kostas, Karlsson, Johan, Lever, Sarah, Li, Xueshan, Lindmark, Helena, Norberg, Monica, Perry, Matthew W. D, Petersen, Jens, Rodrigo Blomqvist, Sandra, Thomas, Matthew, Tyrchan, Christian, Westin Eriksson, Annika, Zlatoidsky, Pavol, Öster, Linda
Published in Journal of medicinal chemistry (28.06.2018)
Published in Journal of medicinal chemistry (28.06.2018)
Get full text
Journal Article
Stabilization of protein-protein interactions in drug discovery
Andrei, Sebastian A., Sijbesma, Eline, Hann, Michael, Davis, Jeremy, O'Mahony, Gavin, Perry, Matthew W. D., Karawajczyk, Anna, Eickhoff, Jan, Brunsveld, Luc, Doveston, Richard G., Milroy, Lech-Gustav, Ottmann, Christian
Published in Expert opinion on drug discovery (02.09.2017)
Published in Expert opinion on drug discovery (02.09.2017)
Get full text
Journal Article
Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties
Over, Björn, McCarren, Patrick, Artursson, Per, Foley, Michael, Giordanetto, Fabrizio, Grönberg, Gunnar, Hilgendorf, Constanze, Lee, Maurice D, Matsson, Pär, Muncipinto, Giovanni, Pellisson, Mélanie, Perry, Matthew W. D, Svensson, Richard, Duvall, Jeremy R, Kihlberg, Jan
Published in Journal of medicinal chemistry (27.03.2014)
Published in Journal of medicinal chemistry (27.03.2014)
Get full text
Journal Article
Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators
Munier, Claire C., De Maria, Leonardo, Edman, Karl, Gunnarsson, Anders, Longo, Marianna, MacKintosh, Carol, Patel, Saleha, Snijder, Arjan, Wissler, Lisa, Brunsveld, Luc, Ottmann, Christian, Perry, Matthew W.D.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
Get full text
Journal Article
Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction
Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
Get full text
Journal Article
A Mouse Model of Zika Virus Sexual Transmission and Vaginal Viral Replication
Tang, William Weihao, Young, Matthew Perry, Mamidi, Anila, Regla-Nava, Jose Angel, Kim, Kenneth, Shresta, Sujan
Published in Cell reports (Cambridge) (20.12.2016)
Published in Cell reports (Cambridge) (20.12.2016)
Get full text
Journal Article
Global Map of Human Impact on Marine Ecosystems
Halpern, Benjamin S, Walbridge, Shaun, Selkoe, Kimberly A, Kappel, Carrie V, Micheli, Fiorenza, D'Agrosa, Caterina, Bruno, John F, Casey, Kenneth S, Ebert, Colin, Fox, Helen E, Fujita, Rod, Heinemann, Dennis, Lenihan, Hunter S, Madin, Elizabeth M.P, Perry, Matthew T, Selig, Elizabeth R, Spalding, Mark, Steneck, Robert, Watson, Reg
Published in Science (American Association for the Advancement of Science) (15.02.2008)
Published in Science (American Association for the Advancement of Science) (15.02.2008)
Get full text
Journal Article