Bisphosphonates used for the treatment of bone disorders inhibit squalene synthase and cholesterol biosynthesis
Amin, D, Cornell, SA, Gustafson, SK, Needle, SJ, Ullrich, JW, Bilder, GE, Perrone, MH
Published in Journal of lipid research (01.11.1992)
Published in Journal of lipid research (01.11.1992)
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Potent quinoxaline-Based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitor
He, Wei, Myers, Michael R., Hanney, Barbara, Spada, Alfred P., Bilder, Glenda, Galzcinski, Helen, Amin, Dilip, Needle, Saul, Page, Ken, Jayyosi, Zaid, Perrone, Mark H.
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
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Pharmacological analysis of alpha-2 adrenergic mechanisms in nociception and ataxia
Luttinger, D, Ferrari, R, Perrone, M H, Haubrich, D R
Published in The Journal of pharmacology and experimental therapeutics (01.03.1985)
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Published in The Journal of pharmacology and experimental therapeutics (01.03.1985)
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Antithrombotic efficacy of a novel factor Xa inhibitor, FXV673, in a canine model of coronary artery thrombolysis
Rebello, Sam S, Bentley, Ross G, Morgan, Suzanne R, Kasiewski, Charles J, Chu, Valeria, Perrone, Mark H, Leadley, Robert J
Published in British journal of pharmacology (01.08.2001)
Published in British journal of pharmacology (01.08.2001)
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Pharmacological Characterization of a Novel Factor Xa Inhibitor, FXV673
Chu, Valeria, Brown, Karen, Colussi, Dennis, Gao, Jingbo, Bostwick, Jeffery, Kasiewski, Charles, Bentley, Ross, Morgan, Susan, Guertin, Kevin, Pauls, Henry W, Gong, Yong, Zulli, Alison, Perrone, Mark H, Dunwiddie, Christopher T, Leadley, Robert J
Published in Thrombosis research (15.08.2001)
Published in Thrombosis research (15.08.2001)
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RPR 107393, a Potent Squalene Synthase Inhibitor and Orally Effective Cholesterol-Lowering Agent: Comparison with Inhibitors of HMG-CoA Reductase
Amin, D, Rutledge, R Z, Needle, S N, Galczenski, H F, Neuenschwander, K, Scotese, A C, Maguire, M P, Bush, R C, Hele, D J, Bilder, G E, Perrone, M H
Published in The Journal of pharmacology and experimental therapeutics (01.05.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1997)
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Identification and Initial Structure−Activity Relationships of a Novel Class of Nonpeptide Inhibitors of Blood Coagulation Factor Xa
Klein, Scott I, Czekaj, Mark, Gardner, Charles J, Guertin, Kevin R, Cheney, Daniel L, Spada, Alfred P, Bolton, Scott A, Brown, Karen, Colussi, Dennis, Heran, Christopher L, Morgan, Suzanne R, Leadley, Robert J, Dunwiddie, Christopher T, Perrone, Mark H, Chu, Valeria
Published in Journal of medicinal chemistry (12.02.1998)
Published in Journal of medicinal chemistry (12.02.1998)
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Demonstration of vasorelaxant activity with an A1-selective adenosine agonist in porcine coronary artery: involvement of potassium channels
MERKEL, L. A, LAPPE, R. W, RIVERA, L. M, COX, B. F, PERRONE, M. H
Published in The Journal of pharmacology and experimental therapeutics (01.02.1992)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.1992)
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Role of short-term inhibition of factor Xa by FXV673 in arterial passivation: a study in a chronic model of thrombosis in conscious dogs
Rebello, S S, Kasiewski, C J, Wang, W, Bentley, R G, Morgan, S R, Chu, V, Colussi, D, Brown, K, Perrone, M H, Leadley, R J
Published in Journal of cardiovascular pharmacology (01.08.2001)
Published in Journal of cardiovascular pharmacology (01.08.2001)
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Tyrphostins inhibit PDGF-induced DNA synthesis and associated early events in smooth muscle cells
Bilder, G E, Krawiec, J A, McVety, K, Gazit, A, Gilon, C, Lyall, R, Zilberstein, A, Levitzki, A, Perrone, M H, Schreiber, A B
Published in The American journal of physiology (01.04.1991)
Published in The American journal of physiology (01.04.1991)
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Inhibition of Repetitive Thrombus Formation in the Stenosed Canine Coronary Artery by Enoxaparin, But Not by Unfractionated Heparin
Leadley, Robert J, Kasiewski, Charles J, Bostwick, Jeffrey S, Bentley, Ross, Dunwiddie, Christopher T, Perrone, Mark H
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.1998)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.1998)
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RPR120844, a novel, specific inhibitor of coagulation factor Xa inhibits venous thrombosis in the rabbit
Bostwick, J S, Bentley, R, Morgan, S, Brown, K, Chu, V, Ewing, W R, Spada, A P, Pauls, H, Perrone, M H, Dunwiddie, C T, Leadley, Jr, R J
Published in Thrombosis and haemostasis (01.01.1999)
Published in Thrombosis and haemostasis (01.01.1999)
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Superiority of Enoxaparin Over Heparin in Combination With a GPIIb/IIIa Receptor Antagonist During Coronary Thrombolysis in Dogs
Rebello, Sam S, Kasiewski, Charles J, Bentley, Ross G, Morgan, Suzanne R, Chu, Valeria, Bostwick, Jeffrey S, Klein, Scott I, Perrone, Mark H, Leadley, Robert J
Published in Thrombosis research (01.05.2001)
Published in Thrombosis research (01.05.2001)
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In Vitro Characterization of a Novel Factor Xa Inhibitor, RPR 130737
Chu, Valeria, Brown, Karen, Colussi, Dennis, Choi, Yong-Mi, Green, Dan, Pauls, Henry W, Spada, Alfred P, Perrone, Mark H, Leadley, Robert J, Dunwiddie, Christopher T
Published in Thrombosis research (01.07.2000)
Published in Thrombosis research (01.07.2000)
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Pharmacodynamic activity and antithrombotic efficacy of RPR120844, a novel inhibitor of coagulation factor Xa
Leadley, Jr, R J, Morgan, S R, Bentley, R, Bostwick, J S, Kasiewski, C J, Heran, C, Chu, V, Brown, K, Moxey, P, Ewing, W R, Pauls, H, Spada, A P, Perrone, M H, Dunwiddie, C T
Published in Journal of cardiovascular pharmacology (01.12.1999)
Published in Journal of cardiovascular pharmacology (01.12.1999)
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Comparison of enoxaparin, hirulog, and heparin as adjunctive antithrombotic therapy during thrombolysis with rtPA in the stenosed canine coronary artery
Leadley, Jr, R J, Kasiewski, C J, Bostwick, J S, Bentley, R, McVey, M J, White, F J, Perrone, M H, Dunwiddie, C T
Published in Thrombosis and haemostasis (01.10.1997)
Published in Thrombosis and haemostasis (01.10.1997)
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