Human Endogenous Retroviruses in Neurological Diseases
Küry, Patrick, Nath, Avindra, Créange, Alain, Dolei, Antonina, Marche, Patrice, Gold, Julian, Giovannoni, Gavin, Hartung, Hans-Peter, Perron, Hervé
Published in Trends in molecular medicine (01.04.2018)
Published in Trends in molecular medicine (01.04.2018)
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Journal Article
The Envelope Protein of a Human Endogenous Retrovirus-W Family Activates Innate Immunity through CD14/TLR4 and Promotes Th1-Like Responses
Rolland, Alexandre, Jouvin-Marche, Evelyne, Viret, Christophe, Faure, Mathias, Perron, Herve, Marche, Patrice N
Published in Journal of Immunology (15.06.2006)
Published in Journal of Immunology (15.06.2006)
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Journal Article
Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4
Duperray, Alain, Barbe, Delphin, Raguenez, Gilda, Weksler, Babette B, Romero, Ignacio A, Couraud, Pierre-Olivier, Perron, Hervé, Marche, Patrice N
Published in International immunology (01.11.2015)
Published in International immunology (01.11.2015)
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Induction of Proinflammatory Multiple Sclerosis-Associated Retrovirus Envelope Protein by Human Herpesvirus-6A and CD46 Receptor Engagement
Charvet, Benjamin, Reynaud, Josephine M, Gourru-Lesimple, Geraldine, Perron, Hervé, Marche, Patrice N, Horvat, Branka
Published in Frontiers in immunology (06.12.2018)
Published in Frontiers in immunology (06.12.2018)
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Journal Article
pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis
Kremer, David, Gruchot, Joel, Weyers, Vivien, Oldemeier, Lisa, Göttle, Peter, Healy, Luke, Jang, Jeong Ho, Xu, Yu Kang T., Volsko, Christina, Dutta, Ranjan, Trapp, Bruce D., Perron, Hervé, Hartung, Hans-Peter, Küry, Patrick
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2019)
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HERV-W ENV antigenemia and correlation of increased anti-SARS-CoV-2 immunoglobulin levels with post-COVID-19 symptoms
Giménez-Orenga, Karen, Pierquin, Justine, Brunel, Joanna, Charvet, Benjamin, Martín-Martínez, Eva, Perron, Hervé, Oltra, Elisa
Published in Frontiers in immunology (27.10.2022)
Published in Frontiers in immunology (27.10.2022)
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Transgenic expression of the HERV-W envelope protein leads to polarized glial cell populations and a neurodegenerative environment
Gruchot, Joel, Lewen, Isabel, Dietrich, Michael, Reiche, Laura, Sindi, Mustafa, Hecker, Christina, Herrero, Felisa, Charvet, Benjamin, Weber-Stadlbauer, Ulrike, Hartung, Hans-Peter, Albrecht, Philipp, Perron, Hervé, Meyer, Urs, Küry, Patrick
Published in Proceedings of the National Academy of Sciences - PNAS (19.09.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (19.09.2023)
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Journal Article
The neutralizing antibody GNbAC1 abrogates HERV-W envelope protein-mediated oligodendroglial maturation blockade
Kremer, David, Förster, Moritz, Schichel, Tanja, Göttle, Peter, Hartung, Hans-Peter, Perron, Hervé, Küry, Patrick
Published in Multiple sclerosis (01.08.2015)
Published in Multiple sclerosis (01.08.2015)
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A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patients
Derfuss, Tobias, Curtin, François, Guebelin, Claudia, Bridel, Claire, Rasenack, Maria, Matthey, Alain, Du Pasquier, Renaud, Schluep, Myriam, Desmeules, Jules, Lang, Alois B, Perron, Hervé, Faucard, Raphael, Porchet, Hervé, Hartung, Hans-Peter, Kappos, Ludwig, Lalive, Patrice H
Published in Multiple sclerosis (01.06.2015)
Published in Multiple sclerosis (01.06.2015)
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Journal Article
Prehistoric enemies within: The contribution of human endogenous retroviruses to neurological diseases. Meeting report: “Second International Workshop on Human Endogenous Retroviruses and Disease”, Washington DC, March 13th and 14th 2017
Kremer, David, Glanzman, Robert, Traboulsee, Anthony, Nath, Avindra, Groc, Laurent, Horwitz, Marc, Göttle, Peter, Perron, Hervé, Gold, Julian, Hartung, Hans-Peter, Küry, Patrick
Published in Multiple sclerosis and related disorders (01.07.2017)
Published in Multiple sclerosis and related disorders (01.07.2017)
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Journal Article
Identification of inflammatory subgroups of schizophrenia and bipolar disorder patients with HERV-W ENV antigenemia by unsupervised cluster analysis
Tamouza, Ryad, Meyer, Urs, Foiselle, Marianne, Richard, Jean-Romain, Wu, Ching-Lien, Boukouaci, Wahid, Le Corvoisier, Philippe, Barrau, Caroline, Lucas, Alexandre, Perron, Hervé, Leboyer, Marion
Published in Translational psychiatry (06.07.2021)
Published in Translational psychiatry (06.07.2021)
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Journal Article
Human endogenous retrovirus type W envelope protein inhibits oligodendroglial precursor cell differentiation
Kremer, David, Schichel, Tanja, Förster, Moritz, Tzekova, Nevena, Bernard, Corinne, van der Valk, Paul, van Horssen, Jack, Hartung, Hans-Peter, Perron, Hervé, Küry, Patrick
Published in Annals of neurology (01.11.2013)
Published in Annals of neurology (01.11.2013)
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Journal Article
MSRV envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: Relevance of GNbAC1 in multiple sclerosis treatment
Madeira, Alexandra, Burgelin, Ingrid, Perron, Hervé, Curtin, Francois, Lang, Alois B, Faucard, Raphael
Published in Journal of neuroimmunology (15.02.2016)
Published in Journal of neuroimmunology (15.02.2016)
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Journal Article
Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination
Göttle, Peter, Förster, Moritz, Gruchot, Joel, Kremer, David, Hartung, Hans Peter, Perron, Hervé, Küry, Patrick
Published in Glia (01.01.2019)
Published in Glia (01.01.2019)
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Rapid diagnosis of human prion disease using streptomycin with tonsil and brain tissues
Quadrio, Isabelle, Ugnon-Café, Séverine, Dupin, Maryline, Esposito, Guillaume, Streichenberger, Nathalie, Krolak-Salmon, Pierre, Vital, Anne, Pellissier, Jean-François, Perret-Liaudet, Armand, Perron, Hervé
Published in Laboratory investigation (01.04.2009)
Published in Laboratory investigation (01.04.2009)
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Human endogenous retrovirus protein activates innate immunity and promotes experimental allergic encephalomyelitis in mice
Perron, Hervé, Dougier-Reynaud, Hei-Lanne, Lomparski, Christina, Popa, Iuliana, Firouzi, Reza, Bertrand, Jean-Baptiste, Marusic, Suzana, Portoukalian, Jacques, Jouvin-Marche, Evelyne, Villiers, Christian L, Touraine, Jean-Louis, Marche, Patrice N
Published in PloS one (06.12.2013)
Published in PloS one (06.12.2013)
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Journal Article
Evidence of the pathogenic HERV-W envelope expression in T lymphocytes in association with the respiratory outcome of COVID-19 patients
Balestrieri, Emanuela, Minutolo, Antonella, Petrone, Vita, Fanelli, Marialaura, Iannetta, Marco, Malagnino, Vincenzo, Zordan, Marta, Vitale, Pietro, Charvet, Benjamin, Horvat, Branka, Bernardini, Sergio, Garaci, Enrico, di Francesco, Paolo, Sinibaldi Vallebona, Paola, Sarmati, Loredana, Grelli, Sandro, Andreoni, Massimo, Perron, Hervé, Matteucci, Claudia
Published in EBioMedicine (01.04.2021)
Published in EBioMedicine (01.04.2021)
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