Selective Tumor Necrosis Factor Receptor I Blockade Is Antiinflammatory and Reveals Immunoregulatory Role of Tumor Necrosis Factor Receptor II in Collagen‐Induced Arthritis
McCann, Fiona E., Perocheau, Dany P., Ruspi, Gerhard, Blazek, Katrina, Davies, Marie L., Feldmann, Marc, Dean, Jonathan L. E., Stoop, A. Allart, Williams, Richard O.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2014)
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Journal Article
IRF5 Is a Specific Marker of Inflammatory Macrophages In Vivo
Perocheau, Dany P., Blazek, Katrina, Byrne, Adam J., Udalova, Irina A., Weiss, Miriam
Published in Mediators of Inflammation (01.01.2013)
Published in Mediators of Inflammation (01.01.2013)
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Journal Article
Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer
Baruteau, Julien, Perocheau, Dany P., Hanley, Joanna, Lorvellec, Maëlle, Rocha-Ferreira, Eridan, Karda, Rajvinder, Ng, Joanne, Suff, Natalie, Diaz, Juan Antinao, Rahim, Ahad A., Hughes, Michael P., Banushi, Blerida, Prunty, Helen, Hristova, Mariya, Ridout, Deborah A., Virasami, Alex, Heales, Simon, Howe, Stewen J., Buckley, Suzanne M. K., Mills, Philippa B., Gissen, Paul, Waddington, Simon N.
Published in Nature communications (29.08.2018)
Published in Nature communications (29.08.2018)
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Journal Article
Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders
Soria, Leandro R, Gurung, Sonam, De Sabbata, Giulia, Perocheau, Dany P, De Angelis, Angela, Bruno, Gemma, Polishchuk, Elena, Paris, Debora, Cuomo, Paola, Motta, Andrea, Orford, Michael, Khalil, Youssef, Eaton, Simon, Mills, Philippa B, Waddington, Simon N, Settembre, Carmine, Muro, Andrés F, Baruteau, Julien, Brunetti‐Pierri, Nicola
Published in EMBO molecular medicine (05.02.2021)
Published in EMBO molecular medicine (05.02.2021)
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Journal Article
Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys
Baruteau, Julien, Cunningham, Sharon C., Yilmaz, Berna Seker, Perocheau, Dany P., Eaglestone, Simon, Burke, Derek, Thrasher, Adrian J., Waddington, Simon N., Lisowski, Leszek, Alexander, Ian E., Gissen, Paul
Published in Molecular therapy. Methods & clinical development (10.12.2021)
Published in Molecular therapy. Methods & clinical development (10.12.2021)
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Journal Article
Continual conscious bioluminescent imaging in freely moving somatotransgenic mice
Karda, Rajvinder, Perocheau, Dany P., Suff, Natalie, Ng, Joanne, Delhove, Juliette M. K. M., Buckley, Suzanne M. K., Richards, Samantha, Counsell, John R., Hagberg, Henrik, Johnson, Mark R., McKay, Tristan R., Waddington, Simon N.
Published in Scientific reports (25.07.2017)
Published in Scientific reports (25.07.2017)
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Journal Article
Re-structuring lentiviral vectors to express genomic RNA via cap-dependent translation
Counsell, John R., De Brabandere, Guillaume, Karda, Rajvinder, Moore, Marc, Greco, Antonio, Bray, Alysha, Diaz, Juan Antinao, Perocheau, Dany P., Mock, Ulrike, Waddington, Simon N.
Published in Molecular therapy. Methods & clinical development (12.03.2021)
Published in Molecular therapy. Methods & clinical development (12.03.2021)
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Journal Article
An In Vitro Whole-Organ Liver Engineering for Testing of Genetic Therapies
Lorvellec, Maëlle, Pellegata, Alessandro Filippo, Maestri, Alice, Turchetta, Chiara, Alvarez Mediavilla, Elena, Shibuya, Soichi, Jones, Brendan, Scottoni, Federico, Perocheau, Dany P., Cozmescu, Andrei Claudiu, Delhove, Juliette M., Kysh, Daniel, Gjinovci, Asllan, Counsell, John R., Heywood, Wendy E., Mills, Kevin, McKay, Tristan R., De Coppi, Paolo, Gissen, Paul
Published in iScience (18.12.2020)
Published in iScience (18.12.2020)
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Journal Article
Fetal gene therapy for neurodegenerative disease of infants
Massaro, Giulia, Mattar, Citra N. Z., Wong, Andrew M. S., Sirka, Ernestas, Buckley, Suzanne M. K., Herbert, Bronwen R., Karlsson, Stefan, Perocheau, Dany P., Burke, Derek, Heales, Simon, Richard-Londt, Angela, Brandner, Sebastian, Huebecker, Mylene, Priestman, David A., Platt, Frances M., Mills, Kevin, Biswas, Arijit, Cooper, Jonathan D., Chan, Jerry K. Y., Cheng, Seng H., Waddington, Simon N., Rahim, Ahad A.
Published in Nature medicine (01.09.2018)
Published in Nature medicine (01.09.2018)
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Journal Article
Age-Related Seroprevalence of Antibodies Against AAV-LK03 in a UK Population Cohort
Perocheau, Dany P, Cunningham, Sharon, Lee, Juhee, Antinao Diaz, Juan, Waddington, Simon N, Gilmour, Kimberly, Eaglestone, Simon, Lisowski, Leszek, Thrasher, Adrian J, Alexander, Ian E, Gissen, Paul, Baruteau, Julien
Published in Human gene therapy (01.01.2019)
Published in Human gene therapy (01.01.2019)
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Journal Article
Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors
Westhaus, Adrian, Cabanes-Creus, Marti, Dilworth, Kimberley L, Zhu, Erhua, Salas Gómez, David, Navarro, Renina G, Amaya, Anais K, Scott, Suzanne, Kwiatek, Magdalena, McCorkindale, Alexandra L, Hayman, Tara E, Frahm, Silke, Perocheau, Dany P, Tran, Bang Manh, Vincan, Elizabeth, Wong, Sharon L, Waters, Shafagh A, Riddiough, Georgina E, Perini, Marcos V, Wilson, Laurence O W, Baruteau, Julien, Diecke, Sebastian, González-Aseguinolaza, Gloria, Santilli, Giorgia, Thrasher, Adrian J, Alexander, Ian E, Lisowski, Leszek
Published in Human gene therapy (01.04.2023)
Published in Human gene therapy (01.04.2023)
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Journal Article
Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy
Vink, Conrad A., Counsell, John R., Perocheau, Dany P., Karda, Rajvinder, Buckley, Suzanne M.K., Brugman, Martijn H., Galla, Melanie, Schambach, Axel, McKay, Tristan R., Waddington, Simon N., Howe, Steven J.
Published in Molecular therapy (02.08.2017)
Published in Molecular therapy (02.08.2017)
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Journal Article
Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis
McCann, Fiona E, Palfreeman, Andrew C, Andrews, Melanie, Perocheau, Dany P, Inglis, Julia J, Schafer, Peter, Feldmann, Marc, Williams, Richard O, Brennan, Fionula M
Published in Arthritis research & therapy (01.01.2010)
Published in Arthritis research & therapy (01.01.2010)
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Journal Article
In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters
Buckley, Suzanne M. K., Delhove, Juliette M. K. M., Perocheau, Dany P., Karda, Rajvinder, Rahim, Ahad A., Howe, Steven J., Ward, Natalie J., Birrell, Mark A., Belvisi, Maria G., Arbuthnot, Patrick, Johnson, Mark R., Waddington, Simon N., McKay, Tristan R.
Published in Scientific reports (03.07.2015)
Published in Scientific reports (03.07.2015)
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Journal Article
Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors
Karda, Rajvinder, Rahim, Ahad A., Wong, Andrew M. S., Suff, Natalie, Diaz, Juan Antinao, Perocheau, Dany P., Tijani, Maha, Ng, Joanne, Baruteau, Julien, Martin, Nuria Palomar, Hughes, Michael, Delhove, Juliette M. K. M., Counsell, John R., Cooper, Jonathan D., Henckaerts, Els, Mckay, Tristan R., Buckley, Suzanne M. K., Waddington, Simon N.
Published in Scientific reports (07.02.2020)
Published in Scientific reports (07.02.2020)
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Journal Article
Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice
Delhove, Juliette M. K. M., Buckley, Suzanne M. K., Perocheau, Dany P., Karda, Rajvinder, Arbuthnot, Patrick, Henderson, Neil C., Waddington, Simon N., McKay, Tristan R.
Published in Scientific reports (03.02.2017)
Published in Scientific reports (03.02.2017)
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Journal Article
609. Transduction of the Central Nervous System with the LTR1 Lentiviral Backbone
Karda, Rajvinder, Counsell, John R., Vink, Conrad A., Perocheau, Dany P., Buckley, Suzanne M.K., Ng, Joanne, Waddington, Simon N., Howe, Steven J.
Published in Molecular therapy (01.05.2016)
Published in Molecular therapy (01.05.2016)
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Journal Article
305. Generation of Light-Producing, Somatic-Transgenic Mice Using Lentivirus and Adeno-Associated Virus Vectors
Karda, Rajvinder, Perocheau, Dany P., Buckley, Suzanne M.K., Delhove, Juliette M. K.M., Hughes, Michael, Rahim, Ahad A., Johnson, Mark R., Ng, Joanne, Sufi, Natalie, Mckay, Tristan R., Waddington, Simon N.
Published in Molecular therapy (01.05.2016)
Published in Molecular therapy (01.05.2016)
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Journal Article
Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors
Westhaus, Adrian, Cabanes-Creus, Marti, Dilworth, Kimberley L, Zhu, Erhua, David Salas Gomez, Navarro, Renina G, Amaya, Anais K, Scott, Suzanne, Kwiatek, Magdalena, Mccorkindale, Alexandra L, Hayman, Tara E, Frahm, Silke, Perocheau, Dany P, Tran, Bang M, Vincan, Elizabeth, Wong, Sharon L, Waters, Shafagh A, Wilson, Laurence O W, Baruteau, Julien, Diecke, Sebastian, Gonzalez-Aseguinolaza, Gloria, Santilli, Giorgia, Thrasher, Adrian J, Alexander, Ian E, Lisowski, Leszek
Published in bioRxiv (30.09.2022)
Published in bioRxiv (30.09.2022)
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Paper
Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders
Soria, Leandro R, Perocheau, Dany P, De Sabbata, Giulia, De Angelis, Angela, Bruno, Gemma, Polishchuk, Elena, Gurung, Sonam, Paris, Debora, Cuomo, Paola, Motta, Andrea, Orford, Michael, Eaton, Simon, Waddington, Simon, Settembre, Carmine, Muro, Andres F, Baruteau, Julien, Brunetti-Pierri, Nicola
Published in bioRxiv (24.07.2020)
Published in bioRxiv (24.07.2020)
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