Regulation of age-associated B cells by IRF5 in systemic autoimmunity
Manni, Michela, Gupta, Sanjay, Ricker, Edd, Chinenov, Yurii, Park, Sung Ho, Shi, Man, Pannellini, Tania, Jessberger, Rolf, Ivashkiv, Lionel B., Pernis, Alessandra B.
Published in Nature immunology (01.04.2018)
Published in Nature immunology (01.04.2018)
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Journal Article
Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data
Orange, Dana E., Agius, Phaedra, DiCarlo, Edward F., Robine, Nicolas, Geiger, Heather, Szymonifka, Jackie, McNamara, Michael, Cummings, Ryan, Andersen, Kathleen M., Mirza, Serene, Figgie, Mark, Ivashkiv, Lionel B., Pernis, Alessandra B., Jiang, Caroline S., Frank, Mayu O., Darnell, Robert B., Lingampali, Nithya, Robinson, William H., Gravallese, Ellen, Bykerk, Vivian P., Goodman, Susan M., Donlin, Laura T.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2018)
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Journal Article
Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice
Ricker, Edd, Manni, Michela, Flores-Castro, Danny, Jenkins, Daniel, Gupta, Sanjay, Rivera-Correa, Juan, Meng, Wenzhao, Rosenfeld, Aaron M., Pannellini, Tania, Bachu, Mahesh, Chinenov, Yurii, Sculco, Peter K., Jessberger, Rolf, Prak, Eline T. Luning, Pernis, Alessandra B.
Published in Nature communications (10.08.2021)
Published in Nature communications (10.08.2021)
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Journal Article
The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity
Yi, Woelsung, Gupta, Sanjay, Ricker, Edd, Manni, Michela, Jessberger, Rolf, Chinenov, Yurii, Molina, Henrik, Pernis, Alessandra B.
Published in Nature communications (15.08.2017)
Published in Nature communications (15.08.2017)
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Journal Article
Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis
Ricker, Edd, Chinenov, Yurii, Pannellini, Tania, Flores-Castro, Danny, Ye, Chao, Gupta, Sanjay, Manni, Michela, Liao, James K, Pernis, Alessandra B
Published in The Journal of clinical investigation (01.07.2020)
Published in The Journal of clinical investigation (01.07.2020)
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Journal Article
Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice
Biswas, Partha S, Gupta, Sanjay, Chang, Emily, Song, Li, Stirzaker, Roslynn A, Liao, James K, Bhagat, Govind, Pernis, Alessandra B
Published in The Journal of clinical investigation (01.09.2010)
Published in The Journal of clinical investigation (01.09.2010)
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Journal Article
Rho Kinases in Autoimmune Diseases
Pernis, Alessandra B, Ricker, Edd, Weng, Chien-Huan, Rozo, Cristina, Yi, Woelsung
Published in Annual review of medicine (14.01.2016)
Published in Annual review of medicine (14.01.2016)
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Journal Article
The RhoA-ROCK pathway in the regulation of T and B cell responses
Ricker, Edd, Chowdhury, Luvana, Yi, Woelsung, Pernis, Alessandra B
Published in F1000 research (2016)
Published in F1000 research (2016)
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Journal Article
IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus
Manni, Michela, Gupta, Sanjay, Nixon, Briana G, Weaver, Casey T, Jessberger, Rolf, Pernis, Alessandra B
Published in PloS one (06.11.2015)
Published in PloS one (06.11.2015)
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Journal Article
Serotonin-1A receptor, a psychiatric disease risk factor, influences offspring immunity via sex-dependent genetic nurture
Chen, Rosa J., Nabila, Anika, Phalke, Swati, Castro, Danny Flores, Toth, Judit Gal, Bergin, Paul, Bastiaans, Jeroen, Stuhlmann, Heidi, Pernis, Alessandra B., Toth, Miklos
Published in iScience (22.12.2022)
Published in iScience (22.12.2022)
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Journal Article
Regulation of TLR4-mediated signaling by IBP/Def6, a novel activator of Rho GTPases
Chen, Qinzhong, Gupta, Sanjay, Pernis, Alessandra B.
Published in Journal of leukocyte biology (01.03.2009)
Published in Journal of leukocyte biology (01.03.2009)
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Journal Article
Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity
Fanzo, Jessica C, Yang, Wen, Jang, So Young, Gupta, Sanjay, Chen, Qinzhong, Siddiq, Ayesha, Greenberg, Steven, Pernis, Alessandra B
Published in The Journal of clinical investigation (01.03.2006)
Published in The Journal of clinical investigation (01.03.2006)
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Journal Article
Molecular mechanisms controlling age‐associated B cells in autoimmunity
Phalke, Swati, Rivera‐Correa, Juan, Jenkins, Daniel, Flores Castro, Danny, Giannopoulou, Evgenia, Pernis, Alessandra B.
Published in Immunological reviews (01.05.2022)
Published in Immunological reviews (01.05.2022)
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Journal Article
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
Rao, Deepak A., Gurish, Michael F., Marshall, Jennifer L., Slowikowski, Kamil, Fonseka, Chamith Y., Liu, Yanyan, Donlin, Laura T., Henderson, Lauren A., Wei, Kevin, Mizoguchi, Fumitaka, Teslovich, Nikola C., Weinblatt, Michael E., Massarotti, Elena M., Coblyn, Jonathan S., Helfgott, Simon M., Lee, Yvonne C., Todd, Derrick J., Bykerk, Vivian P., Goodman, Susan M., Pernis, Alessandra B., Ivashkiv, Lionel B., Karlson, Elizabeth W., Nigrovic, Peter A., Filer, Andrew, Buckley, Christopher D., Lederer, James A., Raychaudhuri, Soumya, Brenner, Michael B.
Published in Nature (London) (02.02.2017)
Published in Nature (London) (02.02.2017)
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Journal Article
Targeting the RhoA-ROCK pathway to reverse T-cell dysfunction in SLE
Rozo, Cristina, Chinenov, Yurii, Maharaj, Reena Khianey, Gupta, Sanjay, Leuenberger, Laura, Kirou, Kyriakos A, Bykerk, Vivian P, Goodman, Susan M, Salmon, Jane E, Pernis, Alessandra B
Published in Annals of the rheumatic diseases (01.04.2017)
Published in Annals of the rheumatic diseases (01.04.2017)
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Journal Article
Modulation of T Cell Cytokine Production by Interferon Regulatory Factor-4
Hu, Chuan-Min, Jang, So Young, Fanzo, Jessica C., Pernis, Alessandra B.
Published in The Journal of biological chemistry (20.12.2002)
Published in The Journal of biological chemistry (20.12.2002)
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Journal Article
Aberrant ROCK activation promotes the development of type I diabetes in NOD mice
Biswas, Partha S., Gupta, Sanjay, Chang, Emily, Bhagat, Govind, Pernis, Alessandra B.
Published in Cellular immunology (01.01.2011)
Published in Cellular immunology (01.01.2011)
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Journal Article
Interleukin‐13 Receptor α1–Mediated Signaling Regulates Age‐Associated/Autoimmune B Cell Expansion and Lupus Pathogenesis
Chen, Zhu, Flores Castro, Danny, Gupta, Sanjay, Phalke, Swati, Manni, Michela, Rivera‐Correa, Juan, Jessberger, Rolf, Zaghouani, Habib, Giannopoulou, Eugenia, Pannellini, Tania, Pernis, Alessandra B.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2022)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2022)
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Journal Article