Amikacin Liposome Inhalation Suspension (ALIS) Penetrates Non-tuberculous Mycobacterial Biofilms and Enhances Amikacin Uptake Into Macrophages
Zhang, Jimin, Leifer, Franziska, Rose, Sasha, Chun, Dung Yu, Thaisz, Jill, Herr, Tracey, Nashed, Mary, Joseph, Jayanthi, Perkins, Walter R, DiPetrillo, Keith
Published in Frontiers in microbiology (16.05.2018)
Published in Frontiers in microbiology (16.05.2018)
Get full text
Journal Article
Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial
Cipolla, David, Zhang, Jimin, Korkmaz, Brice, Chalmers, James D, Basso, Jessica, Lasala, Daniel, Fernandez, Carlos, Teper, Ariel, Mange, Kevin C, Perkins, Walter R, Sullivan, Eugene J
Published in Respiratory research (17.05.2023)
Published in Respiratory research (17.05.2023)
Get full text
Journal Article
Pulmonary Deposition and Elimination of Liposomal Amikacin for Inhalation and Effect on Macrophage Function after Administration in Rats
Malinin, Vladimir, Neville, Mary, Eagle, Gina, Gupta, Renu, Perkins, Walter R
Published in Antimicrobial agents and chemotherapy (01.11.2016)
Published in Antimicrobial agents and chemotherapy (01.11.2016)
Get full text
Journal Article
Brensocatib (an oral, reversible inhibitor of dipeptidyl peptidase-1) attenuates disease progression in two animal models of rheumatoid arthritis
McDonald, Patrick P., Leifer, Franziska Graf, Basso, Jessica, Lasala, Dan, Li, Dedong, Chen, Kuan-Ju, Zhang, Jimin, Perkins, Walter R., Cipolla, David C.
Published in Frontiers in immunology (11.08.2023)
Published in Frontiers in immunology (11.08.2023)
Get full text
Journal Article
Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1, mitigates interferon-α-accelerated lupus nephritis in mice
Chen, Kuan-Ju, Zhang, Jimin, LaSala, Daniel, Basso, Jessica, Chun, Donald, Zhou, Yuchen, McDonald, Patrick P, Perkins, Walter R, Cipolla, David C
Published in Frontiers in immunology (2023)
Published in Frontiers in immunology (2023)
Get full text
Journal Article
Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension
Plaunt, Adam J, Islam, Sadikul, Macaluso, Tony, Gauani, Helena, Baker, Thomas, Chun, Donald, Viramontes, Veronica, Chang, Christina, Corboz, Michel R, Chapman, Richard W, Li, Zhili, Cipolla, David C, Perkins, Walter R, Malinin, Vladimir S
Published in International journal of molecular sciences (07.01.2021)
Published in International journal of molecular sciences (07.01.2021)
Get full text
Journal Article
Therapeutic administration of inhaled INS1009, a treprostinil prodrug formulation, inhibits bleomycin-induced pulmonary fibrosis in rats
Corboz, Michel R., Zhang, Jimin, LaSala, Daniel, DiPetrillo, Keith, Li, Zhili, Malinin, Vladimir, Brower, Jeremy, Kuehl, Philip J., Barrett, Ted E., Perkins, Walter R., Chapman, Richard W.
Published in Pulmonary pharmacology & therapeutics (01.04.2018)
Published in Pulmonary pharmacology & therapeutics (01.04.2018)
Get full text
Journal Article
Effect of Inhalation Profile on Delivery of Treprostinil Palmitil Inhalation Powder
Gauani, Helena, Baker, Thomas, Li, Zhili, Malinin, Vladimir S, Perkins, Walter R, Sullivan, Eugene J, Cipolla, David
Published in Pharmaceutics (01.03.2023)
Published in Pharmaceutics (01.03.2023)
Get full text
Journal Article
Preclinical Investigation of a Lipoglycopeptide Dry Powder Inhalation Therapy for the Treatment of Pulmonary MRSA Infection
Konicek, Donna M, Plaunt, Adam J, Gharse, Sachin, Rose, Sasha J, Dorfman, Arielle, Sabnis, Amruta, Baker, Thomas, Gauani, Helena, Chun, Donald, Li, Zhili, Perkins, Walter R, Cipolla, David, Malinin, Vladimir S
Published in Pharmaceutics (31.08.2023)
Published in Pharmaceutics (31.08.2023)
Get full text
Journal Article
A Gamma Scintigraphy Study to Investigate Lung Deposition and Clearance of Inhaled Amikacin-Loaded Liposomes in Healthy Male Volunteers
WEERS, Jeffry, METZHEISER, Beth, TAYLOR, Glyn, WARREN, Simon, MEERS, Paul, PERKINS, Walter R
Published in Journal of aerosol medicine (01.06.2009)
Published in Journal of aerosol medicine (01.06.2009)
Get full text
Journal Article
Characterization of nebulized liposomal amikacin (Arikace) as a function of droplet size
Li, Zhili, Zhang, Yanling, Wurtz, William, Lee, Jin K, Malinin, Vladimir S, Durwas-Krishnan, Sripriya, Meers, Paul, Perkins, Walter R
Published in Journal of aerosol medicine (01.09.2008)
Published in Journal of aerosol medicine (01.09.2008)
Get full text
Journal Article
Current Overview of the Biology and Pharmacology in Sugen/Hypoxia-Induced Pulmonary Hypertension in Rats
Corboz, Michel R, Nguyen, Tam L, Stautberg, Andy, Cipolla, David, Perkins, Walter R, Chapman, Richard W
Published in Journal of aerosol medicine and pulmonary drug delivery (01.10.2024)
Published in Journal of aerosol medicine and pulmonary drug delivery (01.10.2024)
Get more information
Journal Article
Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension
Corboz, Michel R, Plaunt, Adam J, Malinin, Vladimir S, Li, Zhili, Gauani, Helena, Chun, Donald, Cipolla, David, Perkins, Walter R, Chapman, Richard W
Published in The Journal of pharmacology and experimental therapeutics (01.10.2022)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2022)
Get full text
Journal Article
Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension
Corboz, Michel R., Plaunt, Adam J., Malinin, Vladimir, Li, Zhili, Gauani, Helena, Chun, Donald, Cipolla, David, Perkins, Walter R., Chapman, Richard W.
Published in European journal of pharmacology (05.02.2022)
Published in European journal of pharmacology (05.02.2022)
Get full text
Journal Article
Prostanoid receptor subtypes involved in treprostinil-mediated vasodilation of rat pulmonary arteries and in treprostinil-mediated inhibition of collagen gene expression of human lung fibroblasts
Corboz, Michel R., Salvail, William, Gagnon, Sandra, LaSala, Daniel, Laurent, Charles E., Salvail, Dany, Chen, Kuan-Ju, Cipolla, David, Perkins, Walter R., Chapman, Richard W.
Published in Prostaglandins & other lipid mediators (01.02.2021)
Published in Prostaglandins & other lipid mediators (01.02.2021)
Get full text
Journal Article
Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections
Plaunt, Adam J, Rose, Sasha J, Kang, Jeong Yeon, Chen, Kuan-Ju, LaSala, Daniel, Heckler, Ryan P, Dorfman, Arielle, Smith, Barrett T, Chun, Donald, Viramontes, Veronica, Macaluso, Antonio, Li, Zhili, Zhou, Yuchen, Mark, Lilly, Basso, Jessica, Leifer, Franziska G, Corboz, Michel R, Chapman, Richard W, Cipolla, David, Perkins, Walter R, Malinin, Vladimir S, Konicek, Donna M
Published in Antimicrobial agents and chemotherapy (17.06.2021)
Published in Antimicrobial agents and chemotherapy (17.06.2021)
Get full text
Journal Article
Correction for Plaunt et al., “Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections”
Plaunt, Adam J., Rose, Sasha J., Kang, Jeong Yeon, Chen, Kuan-Ju, LaSala, Daniel, Heckler, Ryan P., Dorfman, Arielle, Smith, Barrett T., Chun, Donald, Viramontes, Veronica, Macaluso, Antonio, Li, Zhili, Zhou, Yuchen, Mark, Lilly, Basso, Jessica, Leifer, Franziska G., Corboz, Michel R., Chapman, Richard W., Cipolla, David, Perkins, Walter R., Malinin, Vladimir S., Konicek, Donna M.
Published in Antimicrobial agents and chemotherapy (15.11.2022)
Published in Antimicrobial agents and chemotherapy (15.11.2022)
Get full text
Journal Article
Preclinical Pharmacology and Pharmacokinetics of Inhaled Hexadecyl-Treprostinil (C16TR), a Pulmonary Vasodilator Prodrug
Corboz, Michel R, Li, Zhili, Malinin, Vladimir, Plaunt, Adam J, Konicek, Donna M, Leifer, Franziska G, Chen, Kuan-Ju, Laurent, Charles E, Yin, Han, Biernat, Marzena C, Salvail, Dany, Zhuang, Jianguo, Xu, Fadi, Curran, Aidan, Perkins, Walter R, Chapman, Richard W
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
Get full text
Journal Article
Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats
Chapman, Richard W., Li, Zhili, Chun, Donald, Gauani, Helena, Malinin, Vladimir, Plaunt, Adam J., Cipolla, David, Perkins, Walter R., Corboz, Michel R.
Published in Pulmonary pharmacology & therapeutics (01.02.2021)
Published in Pulmonary pharmacology & therapeutics (01.02.2021)
Get full text
Journal Article