Industry Perspective on Contemporary Protein-Binding Methodologies: Considerations for Regulatory Drug-Drug Interaction and Related Guidelines on Highly Bound Drugs
Di, Li, Breen, Christopher, Chambers, Rob, Eckley, Sean T., Fricke, Robert, Ghosh, Avijit, Harradine, Paul, Kalvass, J. Cory, Ho, Stacy, Lee, Caroline A., Marathe, Punit, Perkins, Everett J., Qian, Mark, Tse, Susanna, Yan, Zhengyin, Zamek-Gliszczynski, Maciej J.
Published in Journal of pharmaceutical sciences (01.12.2017)
Published in Journal of pharmaceutical sciences (01.12.2017)
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Recommended nomenclature for five mammalian carboxylesterase gene families: human, mouse, and rat genes and proteins
Holmes, Roger S, Wright, Matthew W, Laulederkind, Stanley J. F, Cox, Laura A, Hosokawa, Masakiyo, Imai, Teruko, Ishibashi, Shun, Lehner, Richard, Miyazaki, Masao, Perkins, Everett J, Potter, Phillip M, Redinbo, Matthew R, Robert, Jacques, Satoh, Tetsuo, Yamashita, Tetsuro, Yan, Bingfan, Yokoi, Tsuyoshi, Zechner, Rudolf, Maltais, Lois J
Published in Mammalian genome (01.10.2010)
Published in Mammalian genome (01.10.2010)
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Effect of gastric pH on the pharmacokinetics of a bcs class II compound in dogs: Utilization of an artificial stomach and duodenum dissolution model and gastroplus,™ simulations to predict absorption
Bhattachar, Shobha N., Perkins, Everett J., Tan, Jeffrey S., Burns, Lee J.
Published in Journal of pharmaceutical sciences (01.11.2011)
Published in Journal of pharmaceutical sciences (01.11.2011)
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The Biotransformation of Prasugrel, a New Thienopyridine Prodrug, by the Human Carboxylesterases 1 and 2
Williams, Eric T., Jones, Karen O., Ponsler, G. Douglas, Lowery, Shane M., Perkins, Everett J., Wrighton, Steven A., Ruterbories, Kenneth J., Kazui, Miho, Farid, Nagy A.
Published in Drug metabolism and disposition (01.07.2008)
Published in Drug metabolism and disposition (01.07.2008)
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Characterization of the Expression and Activity of Carboxylesterases 1 and 2 from the Beagle Dog, Cynomolgus Monkey, and Human
WILLIAMS, Eric T, BACON, James A, WRIGHTON, Steven A, PERKINS, Everett J, BENDER, David M, LOWINGER, Jennifer J, GUO, Wen-Kai, EHSANI, Mariam E, XILIANG WANG, HE WANG, QIAN, Yue-Wei, RUTERBORIES, Kenneth J
Published in Drug metabolism and disposition (01.12.2011)
Published in Drug metabolism and disposition (01.12.2011)
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Pharmacokinetics, Metabolism, and Excretion of the Intestinal Peptide Transporter 1 (SLC15A1)-Targeted Prodrug (1S,2S,5R,6S)-2-[(2â²S)-(2-Amino)propionyl]aminobicyclo[3.1.0.]hexen-2,6-dicarboxylic acid (LY544344) in Rats and Dogs: Assessment of First-Pass Bioactivation and Dose Linearity
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The Intestinal Absorption of a Prodrug of the mGlu2/3 Receptor Agonist LY354740 is Mediated by PEPT1: In Situ Rat Intestinal Perfusion Studies
Eriksson, André H., Varma, Manthena V.S., Perkins, Everett J., Zimmerman, Cheryl L.
Published in Journal of pharmaceutical sciences (01.03.2010)
Published in Journal of pharmaceutical sciences (01.03.2010)
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Improved Bioavailability of the mGlu2/3 Receptor Agonist LY354740 Using a Prodrug Strategy: In Vivo Pharmacology of LY544344
Rorick-Kehn, Linda M, Perkins, Everett J, Knitowski, Karen M, Hart, John C, Johnson, Bryan G, Schoepp, Darryle D, McKinzie, David L
Published in The Journal of pharmacology and experimental therapeutics (01.02.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2006)
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Transepithelial Transport of the Group II Metabotropic Glutamate 2/3 Receptor Agonist (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY354740) and Its Prodrug (1S,2S,5R,6S)-2-[(2â²S)-(2â²-Amino)propionyl]aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY544344)
VARMA, Manthena V. S, ERIKSSON, André H, SAWADA, Geri, PAK, Youngeen A, PERKINS, Everett J, ZIMMERMAN, Cheryl L
Published in Drug metabolism and disposition (01.01.2009)
Published in Drug metabolism and disposition (01.01.2009)
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Comparison between Radioanalysis and 19 F Nuclear Magnetic Resonance Spectroscopy in the Determination of Mass Balance, Metabolism, and Distribution of Pefloxacin
Hu, Haitao, Katyayan, Kishore Kumar, Czeskis, Boris A, Perkins, Everett J, Kulanthaivel, Palaniappan
Published in Drug metabolism and disposition (01.04.2017)
Published in Drug metabolism and disposition (01.04.2017)
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Comparison between Radioanalysis and 19F Nuclear Magnetic Resonance Spectroscopy in the Determination of Mass Balance, Metabolism, and Distribution of Pefloxacin
Hu, Haitao, Katyayan, Kishore Kumar, Czeskis, Boris A., Perkins, Everett J., Kulanthaivel, Palaniappan
Published in Drug metabolism and disposition (01.04.2017)
Published in Drug metabolism and disposition (01.04.2017)
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Synthesis, Crystallization, and Biological Evaluation of an Orally Active Prodrug of Gemcitabine
Bender, David M, Bao, Jingqi, Dantzig, Anne H, Diseroad, William D, Law, Kevin L, Magnus, Nicholas A, Peterson, Jeffrey A, Perkins, Everett J, Pu, Yangwei J, Reutzel-Edens, Susan M, Remick, David M, Starling, James J, Stephenson, Gregory A, Vaid, Radhe K, Zhang, Deyi, McCarthy, James R
Published in Journal of medicinal chemistry (26.11.2009)
Published in Journal of medicinal chemistry (26.11.2009)
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Physiologically Based Pharmacokinetic Modelling of Cytochrome P450 2C9-Related Tolbutamide Drug Interactions with Sulfaphenazole and Tasisulam
Perkins, Everett J., Posada, Maria, Kellie Turner, P., Chappell, Jill, Ng, Wee Teck, Twelves, Chris
Published in European journal of drug metabolism and pharmacokinetics (01.06.2018)
Published in European journal of drug metabolism and pharmacokinetics (01.06.2018)
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Efficacy of low-dose oral metronomic dosing of the prodrug of gemcitabine, LY2334737, in human tumor xenografts
Pratt, Susan E, Durland-Busbice, Sara, Shepard, Robert L, Donoho, Gregory P, Starling, James J, Wickremsinhe, Enaksha R, Perkins, Everett J, Dantzig, Anne H
Published in Molecular cancer therapeutics (01.04.2013)
Published in Molecular cancer therapeutics (01.04.2013)
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Dried blood spot sampling: coupling bioanalytical feasibility, blood-plasma partitioning and transferability to in vivo preclinical studies
Wickremsinhe, Enaksha R, Abdul, Basira G, Huang, Naijia H, Richard, John W, Hanes, Jennifer L, Ruterbories, Kenneth J, Perkins, Everett J, Chaudhary, Ajai K
Published in Bioanalysis (01.07.2011)
Published in Bioanalysis (01.07.2011)
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Effect of buffer components and carrier solvents on in vitro activity of recombinant human carboxylesterases
Williams, Eric T., Ehsani, Mariam E., Wang, Xiliang, Wang, He, Qian, Yue-Wei, Wrighton, Steven A., Perkins, Everett J.
Published in Journal of pharmacological and toxicological methods (01.03.2008)
Published in Journal of pharmacological and toxicological methods (01.03.2008)
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Comparison between Radioanalysis and super(19) F Nuclear Magnetic Resonance Spectroscopy in the Determination of Mass Balance, Metabolism, and Distribution of Pefloxacin
Hu, Haitao, Katyayan, Kishore Kumar, Czeskis, Boris A, Perkins, Everett J, Kulanthaivel, Palaniappan
Published in Drug metabolism and disposition (01.04.2017)
Published in Drug metabolism and disposition (01.04.2017)
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2-Methylisoborneol disposition in three strains of catfish: absence of biotransformation
Schlenk, Daniel, Debusk, Bryan, Perkins, Everett J
Published in Fish physiology and biochemistry (01.10.2000)
Published in Fish physiology and biochemistry (01.10.2000)
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