Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease
Nim, Satra, O’Hara, Darren M., Corbi-Verge, Carles, Perez-Riba, Albert, Fujisawa, Kazuko, Kapadia, Minesh, Chau, Hien, Albanese, Federica, Pawar, Grishma, De Snoo, Mitchell L., Ngana, Sophie G., Kim, Jisun, El-Agnaf, Omar M. A., Rennella, Enrico, Kay, Lewis E., Kalia, Suneil K., Kalia, Lorraine V., Kim, Philip M.
Published in Nature communications (19.04.2023)
Published in Nature communications (19.04.2023)
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Journal Article
Testing the length limit of loop grafting in a helical repeat protein
Ripka, Juliane F., Perez-Riba, Albert, Chaturbedy, Piyush K., Itzhaki, Laura S.
Published in Current research in structural biology (01.01.2021)
Published in Current research in structural biology (01.01.2021)
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Journal Article
Computational generation of proteins with predetermined three-dimensional shapes using ProteinSolver
Strokach, Alexey, Becerra, David, Corbi-Verge, Carles, Perez-Riba, Albert, Kim, Philip M.
Published in STAR protocols (18.06.2021)
Published in STAR protocols (18.06.2021)
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Journal Article
Fast and Flexible Protein Design Using Deep Graph Neural Networks
Strokach, Alexey, Becerra, David, Corbi-Verge, Carles, Perez-Riba, Albert, Kim, Philip M.
Published in Cell systems (21.10.2020)
Published in Cell systems (21.10.2020)
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Journal Article
Computational Design of Potent D‑Peptide Inhibitors of SARS-CoV‑2
Valiente, Pedro A, Wen, Han, Nim, Satra, Lee, JinAh, Kim, Hyeon Ju, Kim, Jinhee, Perez-Riba, Albert, Paudel, Yagya Prasad, Hwang, Insu, Kim, Kyun-Do, Kim, Seungtaek, Kim, Philip M
Published in Journal of medicinal chemistry (28.10.2021)
Published in Journal of medicinal chemistry (28.10.2021)
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Journal Article
Unraveling the Mechanics of a Repeat-Protein Nanospring: From Folding of Individual Repeats to Fluctuations of the Superhelix
Synakewicz, Marie, Eapen, Rohan S., Perez-Riba, Albert, Rowling, Pamela J. E., Bauer, Daniela, Weißl, Andreas, Fischer, Gerhard, Hyvönen, Marko, Rief, Matthias, Itzhaki, Laura S., Stigler, Johannes
Published in ACS nano (22.03.2022)
Published in ACS nano (22.03.2022)
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Journal Article
Engineering mono- and multi-valent inhibitors on a modular scaffold† †Electronic supplementary information (ESI) available. See DOI: 10.1039/d0sc03175e
Diamante, Aurora, Chaturbedy, Piyush K., Rowling, Pamela J. E., Kumita, Janet R., Eapen, Rohan S., McLaughlin, Stephen H., de la Roche, Marc, Perez-Riba, Albert, Itzhaki, Laura S.
Published in Chemical science (Cambridge) (17.12.2020)
Published in Chemical science (Cambridge) (17.12.2020)
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Journal Article
Context-Dependent Energetics of Loop Extensions in a Family of Tandem-Repeat Proteins
Perez-Riba, Albert, Lowe, Alan R., Main, Ewan R.G., Itzhaki, Laura S.
Published in Biophysical journal (05.06.2018)
Published in Biophysical journal (05.06.2018)
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Journal Article
Decoupling a tandem-repeat protein: Impact of multiple loop insertions on a modular scaffold
Perez-Riba, Albert, Komives, Elizabeth, Main, Ewan R. G., Itzhaki, Laura S.
Published in Scientific reports (28.10.2019)
Published in Scientific reports (28.10.2019)
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Journal Article
Engineering mono- and multi-valent inhibitors on a modular scaffold
Diamante, Aurora, Chaturbedy, Piyush K, Rowling, Pamela J. E, Kumita, Janet R, Eapen, Rohan S, McLaughlin, Stephen H, Roche, Marc de la, Perez-Riba, Albert, Itzhaki, Laura S
Published in Chemical science (Cambridge) (21.01.2021)
Published in Chemical science (Cambridge) (21.01.2021)
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Journal Article
PyFolding: Open-Source Graphing, Simulation, and Analysis of the Biophysical Properties of Proteins
Lowe, Alan R., Perez-Riba, Albert, Itzhaki, Laura S., Main, Ewan R.G.
Published in Biophysical journal (06.02.2018)
Published in Biophysical journal (06.02.2018)
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Journal Article
Consensus tandem tetratricopeptide repeat proteins are complex superhelical nanosprings
Synakewicz, Marie, Eapen, Rohan, Perez-Riba, Albert, Bauer, Daniela, Weissl, Andreas, Fischer, Gerhard, Hyvonen, Marko, Rief, Matthias, Itzhaki, Laura Susan, Stigler, Johannes
Published in bioRxiv (30.08.2021)
Published in bioRxiv (30.08.2021)
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