Search Results - "Perez Medrano, Arturo" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

A-740003 [N-(1-{[(Cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a Novel and Selective P2X7 Receptor Antagonist, Dose-Dependently Reduces Neuropathic Pain in the Rat

A-740003 [N-(1-{[(Cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a Novel and Selective P2X7 Receptor Antagonist, Dose-Dependently Reduces Neuropathic Pain in the Rat

by Honore, Prisca, Donnelly-Roberts, Diana, Namovic, Marian T, Hsieh, Gin, Zhu, Chang Z, Mikusa, Joe P, Hernandez, Gricelda, Zhong, Chengmin, Gauvin, Donna M, Chandran, Prasant, Harris, Richard, Medrano, Arturo Perez, Carroll, William, Marsh, Kennan, Sullivan, James P, Faltynek, Connie R, Jarvis, Michael F
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)

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Journal Article

[3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors

[3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors

by Donnelly-Roberts, Diana L., Namovic, Marian T., Surber, Bruce, Vaidyanathan, Srirajan X., Perez-Medrano, Arturo, Wang, Ying, Carroll, William A., Jarvis, Michael F.
Published in Neuropharmacology (01.01.2009)

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Journal Article

Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle

Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle

by Malysz, John, Buckner, Steven A, Daza, Anthony V, Milicic, Ivan, Perez-Medrano, Arturo, Gopalakrishnan, Murali
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.05.2004)

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Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X(7) antagonists

Structure-activity relationship studies on a series of novel, substituted 1-benzyl-5-phenyltetrazole P2X(7) antagonists

by Nelson, Derek W., Gregg, Robert J., Kort, Michael E., Perez-Medrano, Arturo, Voight, Eric A., Wang, Ying, Grayson, George, Namovic, Marian T., Donnelly-Roberts, Diana L., Niforatos, Wende, Honore, Prisca, Jarvis, Michael F., Faltynek, Connie R., Carroll, William A.
Published in Journal of medicinal chemistry (15.06.2006)

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The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1αβ knockout mice

The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1αβ knockout mice

by Honore, Prisca, Donnelly-Roberts, Diana, Namovic, Marian, Zhong, Chengmin, Wade, Carrie, Chandran, Prasant, Zhu, Chang, Carroll, William, Perez-Medrano, Arturo, Iwakura, Yoichiro, Jarvis, Michael F.
Published in Behavioural brain research (01.12.2009)

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Convergent, enantiospecific total synthesis of the novel cyclodepsipeptide (+)-jasplakinolide (jaspamide)

Convergent, enantiospecific total synthesis of the novel cyclodepsipeptide (+)-jasplakinolide (jaspamide)

by Grieco, Paul A, Hon, Yung Son, Perez-Medrano, Arturo
Published in Journal of the American Chemical Society (01.03.1988)

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Journal Article

Structure−Activity Relationship Studies on a Series of Novel, Substituted 1-Benzyl-5-phenyltetrazole P2X7 Antagonists

Structure−Activity Relationship Studies on a Series of Novel, Substituted 1-Benzyl-5-phenyltetrazole P2X7 Antagonists

by Nelson, Derek W, Gregg, Robert J, Kort, Michael E, Perez-Medrano, Arturo, Voight, Eric A, Wang, Ying, Grayson, George, Namovic, Marian T, Donnelly-Roberts, Diana L, Niforatos, Wende, Honore, Prisca, Jarvis, Michael F, Faltynek, Connie R, Carroll, William A
Published in Journal of medicinal chemistry (15.06.2006)

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Journal Article

SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS

SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS

by FROST JENNIFER M, PATEL MEENA, DART MICHAEL J, KOLASA TEODOZYJ, LIU BO, WANG XUEQING, PEREZ MEDRANO ARTURO, LATSHAW STEVEN P, PEDDI SRIDHAR, LI TONGMEI, NELSON DEREK W, CARROLL WILLIAM A
Year of Publication 09.06.2011

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Patent

Synthesis of the highly oxygenated ergostane type steroid (+)-withanolide E

Synthesis of the highly oxygenated ergostane type steroid (+)-withanolide E

by Perez-Medrano, Arturo, Grieco, Paul A
Published in Journal of the American Chemical Society (1991)

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Journal Article

Discovery and Biological Evaluation of Novel Cyanoguanidine P2X(7) Antagonists with Analgesic Activity in a Rat Model of Neuropathic Pain

Discovery and Biological Evaluation of Novel Cyanoguanidine P2X(7) Antagonists with Analgesic Activity in a Rat Model of Neuropathic Pain

by Perez-Medrano, Arturo, Donnelly-Roberts, Diana L., Honore, Prisca, Hsieh, Gin C., Namovic, Marian T., Peddi, Sridhar, Shuai, Qi, Wang, Ying, Faltynek, Connie R., Jarvis, Michael F., Carroll, William A.
Published in Journal of medicinal chemistry (28.05.2009)

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Journal Article

Discovery and Biological Evaluation of Novel Cyanoguanidine P2X7 Antagonists with Analgesic Activity in a Rat Model of Neuropathic Pain

Discovery and Biological Evaluation of Novel Cyanoguanidine P2X7 Antagonists with Analgesic Activity in a Rat Model of Neuropathic Pain

by Perez-Medrano, Arturo, Donnelly-Roberts, Diana L, Honore, Prisca, Hsieh, Gin C, Namovic, Marian T, Peddi, Sridhar, Shuai, Qi, Wang, Ying, Faltynek, Connie R, Jarvis, Michael F, Carroll, William A
Published in Journal of medicinal chemistry (28.05.2009)

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Journal Article

Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X(7) antagonists

Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X(7) antagonists

by Perez-Medrano, Arturo, Donnelly-Roberts, Diana L, Florjancic, Alan S, Nelson, Derek W, Li, Tongmei, Namovic, Marian T, Peddi, Sridhar, Faltynek, Connie R, Jarvis, Michael F, Carroll, William A
Published in Bioorganic & medicinal chemistry letters (01.06.2011)

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Journal Article

KCNQ2/3 openers show differential selectivity and site of action across multiple KCNQ channels

KCNQ2/3 openers show differential selectivity and site of action across multiple KCNQ channels

by Zhang, Di, Thimmapaya, Rama, Zhang, Xu-Feng, Anderson, David J., Baranowski, John L., Scanio, Marc, Perez-Medrano, Arturo, Peddi, Sridhar, Wang, Zhi, Patel, Jyoti R., DeGoey, David A., Gopalakrishnan, Murali, Honore, Prisca, Yao, Betty B., Surowy, Carol S.
Published in Journal of neuroscience methods (30.08.2011)

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Journal Article

Novel and potent 3-(2,3-dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 antagonists

Novel and potent 3-(2,3-dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 antagonists

by CARROLL, William A, KALVIN, Douglas M, PEREZ MEDRANO, Arturo, FLORJANCIC, Alan S, YING WANG, DONNELLY-ROBERTS, Diana L, NAMOVIC, Marian T, GRAYSON, George, HONORE, Prisca, JARVIS, Michael F
Published in Bioorganic & medicinal chemistry letters (15.07.2007)

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Journal Article

Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists

Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists

by Florjancic, Alan S, Peddi, Sridhar, Perez-Medrano, Arturo, Li, Biqin, Namovic, Marian T, Grayson, George, Donnelly-Roberts, Diana L, Jarvis, Michael F, Carroll, William A
Published in Bioorganic & medicinal chemistry letters (15.03.2008)

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Journal Article

Design and Synthesis of Novel Cyanoguanidine ATP-Sensitive Potassium Channel Openers for the Treatment of Overactive Bladder

Design and Synthesis of Novel Cyanoguanidine ATP-Sensitive Potassium Channel Openers for the Treatment of Overactive Bladder

by Perez‐Medrano, Arturo, et al, et al
Published in ChemInform (04.05.2004)

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Journal Article

Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X sub(7 antagonists)

Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X sub(7 antagonists)

by Perez-Medrano, Arturo, Donnelly-Roberts, Diana L, Florjancic, Alan S, Nelson, Derek W, Li, Tongmei, Namovic, Marian T, Peddi, Sridhar, Faltynek, Connie R, Jarvis, Michael F, Carroll, William A
Published in Bioorganic & medicinal chemistry letters (01.06.2011)

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Journal Article

Novel and Potent 3-(2,3-Dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 Antagonists

Novel and Potent 3-(2,3-Dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 Antagonists

by Carroll, William A., Kalvin, Douglas M., Perez-Medrano, Arturo, Florjancic, Alan S., Wang, Ying, Donnelly-Roberts, Diana L., Namovic, Marian T., Grayson, George, Honore, Prisca, Jarvis, Michael F.
Published in ChemInform (30.10.2007)

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Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1 H-tetrazol-5-amine P2X 7 antagonists

Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1 H-tetrazol-5-amine P2X 7 antagonists

by Perez-Medrano, Arturo, Donnelly-Roberts, Diana L., Florjancic, Alan S., Nelson, Derek W., Li, Tongmei, Namovic, Marian T., Peddi, Sridhar, Faltynek, Connie R., Jarvis, Michael F., Carroll, William A.
Published in Bioorganic & medicinal chemistry letters (2011)

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Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X₇ antagonists

Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X₇ antagonists

by Perez-Medrano, Arturo, Donnelly-Roberts, Diana L, Florjancic, Alan S, Nelson, Derek W, Li, Tongmei, Namovic, Marian T, Peddi, Sridhar, Faltynek, Connie R, Jarvis, Michael F, Carroll, William A
Published in Bioorganic & medicinal chemistry letters (01.06.2011)

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