Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics
Pillon, Monica C., Frazier, Meredith N., Dillard, Lucas B., Williams, Jason G., Kocaman, Seda, Krahn, Juno M., Perera, Lalith, Hayne, Cassandra K., Gordon, Jacob, Stewart, Zachary D., Sobhany, Mack, Deterding, Leesa J., Hsu, Allen L., Dandey, Venkata P., Borgnia, Mario J., Stanley, Robin E.
Published in Nature communications (27.01.2021)
Published in Nature communications (27.01.2021)
Get full text
Journal Article
Characterization of Estrogenic and Androgenic Activities for Bisphenol A-like Chemicals (BPs): In Vitro Estrogen and Androgen Receptors Transcriptional Activation, Gene Regulation, and Binding Profiles
Pelch, Katherine E, Li, Yin, Perera, Lalith, Thayer, Kristina A, Korach, Kenneth S
Published in Toxicological sciences (01.11.2019)
Published in Toxicological sciences (01.11.2019)
Get full text
Journal Article
Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling
Mutoh, Shingo, Sobhany, Mack, Moore, Rick, Perera, Lalith, Pedersen, Lee, Sueyoshi, Tatsuya, Negishi, Masahiko
Published in Science signaling (07.05.2013)
Published in Science signaling (07.05.2013)
Get more information
Journal Article
An Ancient Family of RNA-Binding Proteins: Still Important
Wells, Melissa L., Perera, Lalith, Blackshear, Perry J.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.04.2017)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.04.2017)
Get full text
Journal Article
A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop
Wang, Huanchen, Perera, Lalith, Jork, Nikolaus, Zong, Guangning, Riley, Andrew M., Potter, Barry V. L., Jessen, Henning J., Shears, Stephen B.
Published in Nature communications (25.04.2022)
Published in Nature communications (25.04.2022)
Get full text
Journal Article
Phosphopeptide interactions of the Nbs1 N-terminal FHA-BRCT1/2 domains
Kim, Kyungmin, Kirby, Thomas W., Perera, Lalith, London, Robert E.
Published in Scientific reports (27.04.2021)
Published in Scientific reports (27.04.2021)
Get full text
Journal Article
Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide
Freudenthal, Bret D., Beard, William A., Perera, Lalith, Shock, David D., Kim, Taejin, Schlick, Tamar, Wilson, Samuel H.
Published in Nature (London) (29.01.2015)
Published in Nature (London) (29.01.2015)
Get full text
Journal Article
GATA3 zinc finger 2 mutations reprogram the breast cancer transcriptional network
Takaku, Motoki, Grimm, Sara A., Roberts, John D., Chrysovergis, Kaliopi, Bennett, Brian D., Myers, Page, Perera, Lalith, Tucker, Charles J., Perou, Charles M., Wade, Paul A.
Published in Nature communications (13.03.2018)
Published in Nature communications (13.03.2018)
Get full text
Journal Article
Ligand induced dissociation of the AR homodimer precedes AR monomer translocation to the nucleus
Shizu, Ryota, Yokobori, Kosuke, Perera, Lalith, Pedersen, Lee, Negishi, Masahiko
Published in Scientific reports (13.11.2019)
Published in Scientific reports (13.11.2019)
Get full text
Journal Article
Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U
Frazier, Meredith N, Dillard, Lucas B, Krahn, Juno M, Perera, Lalith, Williams, Jason G, Wilson, Isha M, Stewart, Zachary D, Pillon, Monica C, Deterding, Leesa J, Borgnia, Mario J, Stanley, Robin E
Published in Nucleic Acids Research (27.09.2021)
Published in Nucleic Acids Research (27.09.2021)
Get full text
Journal Article
Web Resource
Determining the endocrine disruption potential of industrial chemicals using an integrative approach: Public databases, in vitro exposure, and modeling receptor interactions
Alofe, Olubusayo, Kisanga, Edwina, Inayat-Hussain, Salmaan H., Fukumura, Masao, Garcia-Milian, Rolando, Perera, Lalith, Vasiliou, Vasilis, Whirledge, Shannon
Published in Environment international (01.10.2019)
Published in Environment international (01.10.2019)
Get full text
Journal Article
Requirement for transient metal ions revealed through computational analysis for DNA polymerase going in reverse
Perera, Lalith, Freudenthal, Bret D., Beard, William A., Shock, David D., Pedersen, Lee G., Wilson, Samuel H.
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (22.09.2015)
Get full text
Journal Article
Dephosphorylation of Threonine 38 Is Required for Nuclear Translocation and Activation of Human Xenobiotic Receptor CAR (NR1I3)
Mutoh, Shingo, Osabe, Makoto, Inoue, Kaoru, Moore, Rick, Pedersen, Lee, Perera, Lalith, Rebolloso, Yvette, Sueyoshi, Tatsuya, Negishi, Masahiko
Published in The Journal of biological chemistry (11.12.2009)
Published in The Journal of biological chemistry (11.12.2009)
Get full text
Journal Article
Mitochondrial single-stranded DNA binding protein novel de novo SSBP1 mutation in a child with single large-scale mtDNA deletion (SLSMD) clinically manifesting as Pearson, Kearns-Sayre, and Leigh syndromes
Gustafson, Margaret A, McCormick, Elizabeth M, Perera, Lalith, Longley, Matthew J, Bai, Renkui, Kong, Jianping, Dulik, Matthew, Shen, Lishuang, Goldstein, Amy C, McCormack, Shana E, Laskin, Benjamin L, Leroy, Bart P, Ortiz-Gonzalez, Xilma R, Ellington, Meredith G, Copeland, William C, Falk, Marni J
Published in PloS one (03.09.2019)
Published in PloS one (03.09.2019)
Get full text
Journal Article
Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function
Jongwattanapisan, Prapaporn, Terajima, Masahiko, Miguez, Patricia A., Querido, William, Nagaoka, Hideaki, Sumida, Noriko, Gurysh, Elizabeth Grace, Ainslie, Kristy M., Pleshko, Nancy, Perera, Lalith, Yamauchi, Mitsuo
Published in Scientific reports (04.05.2018)
Published in Scientific reports (04.05.2018)
Get full text
Journal Article