Avelumab plus axitinib versus sunitinib in advanced renal cell carcinoma: biomarker analysis of the phase 3 JAVELIN Renal 101 trial
Motzer, Robert J., Robbins, Paul B., Powles, Thomas, Albiges, Laurence, Haanen, John B., Larkin, James, Mu, Xinmeng Jasmine, Ching, Keith A., Uemura, Motohide, Pal, Sumanta K., Alekseev, Boris, Gravis, Gwenaelle, Campbell, Matthew T., Penkov, Konstantin, Lee, Jae Lyun, Hariharan, Subramanian, Wang, Xiao, Zhang, Weidong, Wang, Jing, Chudnovsky, Aleksander, di Pietro, Alessandra, Donahue, Amber C., Choueiri, Toni K.
Published in Nature medicine (01.11.2020)
Published in Nature medicine (01.11.2020)
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Avelumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma
Motzer, Robert J, Penkov, Konstantin, Haanen, John, Rini, Brian, Albiges, Laurence, Campbell, Matthew T, Venugopal, Balaji, Kollmannsberger, Christian, Negrier, Sylvie, Uemura, Motohide, Lee, Jae L, Vasiliev, Aleksandr, Miller, Wilson H, Gurney, Howard, Schmidinger, Manuela, Larkin, James, Atkins, Michael B, Bedke, Jens, Alekseev, Boris, Wang, Jing, Mariani, Mariangela, Robbins, Paul B, Chudnovsky, Aleksander, Fowst, Camilla, Hariharan, Subramanian, Huang, Bo, di Pietro, Alessandra, Choueiri, Toni K
Published in The New England journal of medicine (21.03.2019)
Published in The New England journal of medicine (21.03.2019)
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Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial
Gogishvili, Miranda, Melkadze, Tamar, Makharadze, Tamta, Giorgadze, Davit, Dvorkin, Mikhail, Penkov, Konstantin, Laktionov, Konstantin, Nemsadze, Gia, Nechaeva, Marina, Rozhkova, Irina, Kalinka, Ewa, Gessner, Christian, Moreno-Jaime, Brizio, Passalacqua, Rodolfo, Li, Siyu, McGuire, Kristina, Kaul, Manika, Paccaly, Anne, Quek, Ruben G. W., Gao, Bo, Seebach, Frank, Weinreich, David M., Yancopoulos, George D., Lowy, Israel, Gullo, Giuseppe, Rietschel, Petra
Published in Nature medicine (01.11.2022)
Published in Nature medicine (01.11.2022)
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Pharmacokinetics, safety, and efficacy of an alternative dosing regimen of sasanlimab in participants with advanced NSCLC and other malignancies
Penkov, Konstantin, Bondarenko, Igor, Saenko, Daria Viktorovna, Kulyaba, Yaroslav, Guo, Jun, Gong, Yi, Yamamoto, Noboru, Hotko, Yevhen Stepanovych, Boyko, Vasyl, Fadeeva, Natalya Vladimirovna, Ursol, Grygorii Mykolaiovych, Ahn, Hee Kyung, Kislov, Nikolay Viktorovich, Shen, Chia-I, Davis, Craig, Kowalski, Karey, Michelon, Elisabete, Pavlov, Dmitri, Hirohashi, Tomoko, Cho, Byoung Chul
Published in Therapeutic advances in medical oncology (01.01.2024)
Published in Therapeutic advances in medical oncology (01.01.2024)
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Efficacy and Safety of Rovalpituzumab Tesirine Compared With Topotecan as Second-Line Therapy in DLL3-High SCLC: Results From the Phase 3 TAHOE Study
Blackhall, Fiona, Jao, Kevin, Greillier, Laurent, Cho, Byoung Chul, Penkov, Konstantin, Reguart, Noemi, Majem, Margarita, Nackaerts, Kristiaan, Syrigos, Konstantinos, Hansen, Karin, Schuette, Wolfgang, Cetnar, Jeremy, Cappuzzo, Federico, Okamoto, Isamu, Erman, Mustafa, Langer, Seppo W., Kato, Terufumi, Groen, Harry, Sun, Zhaowen, Luo, Yan, Tanwani, Poonam, Caffrey, Laura, Komarnitsky, Philip, Reinmuth, Niels
Published in Journal of thoracic oncology (01.09.2021)
Published in Journal of thoracic oncology (01.09.2021)
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Post Hoc Analysis of Lorlatinib Intracranial Efficacy and Safety in Patients With ALK -Positive Advanced Non-Small-Cell Lung Cancer From the Phase III CROWN Study
Solomon, Benjamin J, Bauer, Todd M, Ignatius Ou, Sai-Hong, Liu, Geoffrey, Hayashi, Hidetoshi, Bearz, Alessandra, Penkov, Konstantin, Wu, Yi-Long, Arrieta, Oscar, Jassem, Jacek, Calella, Anna M, Peltz, Gerson, Polli, Anna, Thurm, Holger, Mok, Tony
Published in Journal of clinical oncology (01.11.2022)
Published in Journal of clinical oncology (01.11.2022)
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Effect of First-Line Serplulimab vs Placebo Added to Chemotherapy on Survival in Patients With Extensive-Stage Small Cell Lung Cancer: The ASTRUM-005 Randomized Clinical Trial
Cheng, Ying, Han, Liang, Wu, Lin, Chen, Jun, Sun, Hongmei, Wen, Guilan, Ji, Yinghua, Dvorkin, Mikhail, Shi, Jianhua, Pan, Zhijie, Shi, Jinsheng, Wang, Xicheng, Bai, Yuansong, Melkadze, Tamar, Pan, Yueyin, Min, Xuhong, Viguro, Maksym, Li, Xingya, Zhao, Yanqiu, Yang, Junquan, Makharadze, Tamta, Arkania, Ekaterine, Kang, Wenying, Wang, Qingyu, Zhu, Jun
Published in JAMA : the journal of the American Medical Association (27.09.2022)
Published in JAMA : the journal of the American Medical Association (27.09.2022)
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Veliparib in Combination with Carboplatin and Etoposide in Patients with Treatment-Naïve Extensive-Stage Small Cell Lung Cancer: A Phase 2 Randomized Study
Byers, Lauren Averett, Bentsion, Dmitry, Gans, Steven, Penkov, Konstantin, Son, ChoonHee, Sibille, Anne, Owonikoko, Taofeek K, Groen, Harry J M, Gay, Carl M, Fujimoto, Junya, de Groot, Patricia, Dunbar, Martin, Kang, Kingston, He, Lei, Sehgal, Vasudha, Glasgow, Jaimee, Bach, Bruce Allen, Ellis, Peter M
Published in Clinical cancer research (15.07.2021)
Published in Clinical cancer research (15.07.2021)
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First-line encorafenib plus binimetinib and pembrolizumab for advanced BRAF V600-mutant melanoma: Safety lead-in results from the randomized phase III STARBOARD study
Dudnichenko, Oleksandr, Penkov, Konstantin, McKean, Meredith, Mandalà, Mario, Kukushkina, Mariia, Panella, Timothy, Csőszi, Tibor, Gerletti, Paola, Thakur, Mahgull, Polli, Anna, di Pietro, Alessandra, Schadendorf, Dirk
Published in European journal of cancer (1990) (01.12.2024)
Published in European journal of cancer (1990) (01.12.2024)
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Cemiplimab Plus Chemotherapy Versus Chemotherapy Alone in Advanced NSCLC: 2-Year Follow-Up From the Phase 3 EMPOWER-Lung 3 Part 2 Trial
Makharadze, Tamta, Gogishvili, Miranda, Melkadze, Tamar, Baramidze, Ana, Giorgadze, Davit, Penkov, Konstantin, Laktionov, Konstantin, Nemsadze, Gia, Nechaeva, Marina, Rozhkova, Irina, Kalinka, Ewa, Li, Siyu, Li, Yuntong, Kaul, Manika, Quek, Ruben G.W., Pouliot, Jean-Francois, Seebach, Frank, Lowy, Israel, Gullo, Giuseppe, Rietschel, Petra
Published in Journal of thoracic oncology (01.06.2023)
Published in Journal of thoracic oncology (01.06.2023)
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Efficacy of Lorlatinib in Treatment-Naive Patients With ALK-Positive Advanced NSCLC in Relation to EML4::ALK Variant Type and ALK With or Without TP53 Mutations
Bearz, Alessandra, Martini, Jean-François, Jassem, Jacek, Kim, Sang-We, Chang, Gee-Chen, Shaw, Alice T., Shepard, Deborah A., Dall’O’, Elisa, Polli, Anna, Thurm, Holger, Zalcman, Gerard, Garcia Campelo, Maria Rosario, Penkov, Konstantin, Hayashi, Hidetoshi, Solomon, Benjamin J.
Published in Journal of thoracic oncology (01.11.2023)
Published in Journal of thoracic oncology (01.11.2023)
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Efficacy and safety of trastuzumab deruxtecan (T-DXd) in patients (pts) with HER2-expressing solid tumors: Results from the bladder cohort of the DESTINY-PanTumor02 (DP-02) study
Wysocki, Piotr Jan, Jung, Kyung Hae, Oh, Do-Youn, Doroshow, Deborah Blythe, Artamonova, Elena, Mammatas, Lemonitsa, SU, Po-Jung, Moiseyenko, Vladimir, Penkov, Konstantin, Stroyakovskiy, Daniil, Bartolome, Jorge, Siena, Salvatore, Fielding, Anitra, Jung, Lindsey, Michelini, Flavia, Puvvada, Soham D., Makker, Vicky
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Phase 3 trial of lorlatinib in treatment-naive patients (Pts) with ALK -positive advanced non–small cell lung cancer (NSCLC): Comprehensive plasma and tumor genomic analyses
Bearz, Alessandra, Martini, Jean-Francois, Jassem, Jacek, Kim, Sang-We, Chang, Gee-Chen, Shaw, Alice Tsang, Shepard, Deborah, Dall’O, Elisa, Polli, Anna, Thurm, Holger C., Zalcman, Gerard, Campelo, Rosario Garcia, Penkov, Konstantin, Hayashi, Hidetoshi, Solomon, Benjamin J.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Quality of life with cemiplimab plus chemotherapy for first‐line treatment of advanced non–small cell lung cancer: Patient‐reported outcomes from phase 3 EMPOWER‐Lung 3
Makharadze, Tamta, Quek, Ruben G. W., Melkadze, Tamar, Gogishvili, Miranda, Ivanescu, Cristina, Giorgadze, Davit, Dvorkin, Mikhail, Penkov, Konstantin, Laktionov, Konstantin, Nemsadze, Gia, Nechaeva, Marina, Rozhkova, Irina, Kalinka, Ewa, Gessner, Christian, Moreno‐Jaime, Brizio, Passalacqua, Rodolfo, Konidaris, Gerasimos, Rietschel, Petra, Gullo, Giuseppe
Published in Cancer (15.07.2023)
Published in Cancer (15.07.2023)
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Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer with PD-L1 ≥ 1 %: A subgroup analysis from the EMPOWER-Lung 3 part 2 trial
Baramidze, Ana, Makharadze, Tamta, Gogishvili, Miranda, Melkadze, Tamar, Giorgadze, Davit, Penkov, Konstantin, Laktionov, Konstantin, Nemsadze, Gia, Nechaeva, Marina, Rozhkova, Irina, Kalinka, Ewa, AG McIntyre, Debra, Perez, Javier, Kaul, Manika, Quek, Ruben G.W., Seebach, Frank, Rietschel, Petra, Pouliot, Jean-Francois
Published in Lung cancer (Amsterdam, Netherlands) (01.07.2024)
Published in Lung cancer (Amsterdam, Netherlands) (01.07.2024)
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Abstract CT138: Molecular markers in a phase I dose expansion study of PF-06801591 in locally advanced or metastatic non-small-cell lung cancer and urothelial carcinoma
Cho, Byoung Chul, Penkov, Konstantin, Bondarenko, Igor, Pikiel, Joanna, Ahn, Hee Kyung, Forgie, Alison, Jacobs, Ira, Bonato, Vinicius, Mu, Xinmeng Jasmine, Ching, Keith, Chou, Jeffrey, Johnson, Melissa L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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A multi-center, open-label, randomized dose expansion study of PF-06821497, a potent and selective inhibitor of enhancer of zeste homolog 2 (EZH2), in patients with metastatic castration-resistant prostate cancer (mCRPC)
Calvo, Mariona, Penkov, Konstantin, Spira, Alexander I., Moreno Candilejo, Irene, Shore, Neal D., Zhang, Tian, Mellado-Gonzalez, Begoña, Alonso Gordoa, Teresa, Paz-Ares Rodriguez, Luis, Tarantolo, Stefano R., Soto, Juan José, Alter, Robert S., Andreu-Vieyra, Claudia, Bowler, Timothy, Maity, Arnab K, Hariharan, Subramanian, Schweizer, Michael Thomas
Published in Journal of clinical oncology (20.02.2023)
Published in Journal of clinical oncology (20.02.2023)
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Abstract LB043: Efficacy of Lorlatinib in Treatment-Naïve Patients (pts) With ALK-Positive Advanced Non-Small Cell Lung Cancer (NSCLC) in Relation to EML4-ALK Variant Type and ALK Mutations
Bearz, Alessandra, Martini, Jean-François, Jassem, Jacek, Kim, Sang-We, Chang, Gee-Chen, Shaw, Alice, Shepard, Deborah, Dall'O', Elisa, Polli, Anna, Thurm, Holger, Zalcman, Gerard, Campelo, Maria Rosario Garcia, Penkov, Konstantin, Hayashi, Hidetoshi, Solomon, Benjamin J.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Final Results of RIGHT Choice: Ribociclib Plus Endocrine Therapy Versus Combination Chemotherapy in Premenopausal Women With Clinically Aggressive Hormone Receptor–Positive/Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer
Lu, Yen-Shen, Mahidin, Eznal Izwadi Bin Mohd, Azim, Hamdy, Eralp, Yesim, Yap, Yoon Sim, Im, Seock-Ah, Rihani, Julie, Gokmen, Erhan, El Bastawisy, Ahmed, Karadurmus, Nuri, Lim, Yueh Ni, Lim, Chun Sen, Duc, Le Thanh, Chung, Wei-Pang, Babu, K. Govind, Penkov, Konstantin, Bowles, James, Alfaro, Teresa Delgar, Wu, Jiwen, Gao, Melissa, Slimane, Khemaies, El Saghir, Nagi S., Alsayed, Adher, El Bastawisy, Ahmed, Gogia, Ajay, Charoentum, Chaiyut, Goswami, Chanchal, Liu, Chien-Ting, Lim, Chun Sen, Artamonova, Elena, Gokmen, Erhan, Namal, Esat, Mohd Mahidin, Eznal Izwadi, Farhat, Fadi, Li Tze, Flora Chong, Başaran, Gül, Harputluoglu, Hakan, Azim, Hamdy Abdel, Abdelrazeq, Hikmat, ElGhazaly, Hesham, Babu, K. Govind, Penkov, Konstantin, Duc, Le Thanh, Tseng, Ling-Ming, Osmanova, Liudmila, Zhukova, Ludmila, Konatum, Meher Lakshmi, Nahit Şendur, Mehmet Ali, Dai, Ming-Shen, Ayoubi, Mona, El-Saghir, Nagi, Prasongsook, Naiyarat, Parinyanitikul, Napa, Volkov, Nikita, Karadurmus, Nuri, Sunpaweravong, Patrapim, Siang Ang, Peter Cher, Voon, Pei Jye, Gaafar, Rabab, Motagaly, Rasha Abdel, Khanyile, Richard, Goksu, Sema Sezgin, Chen, Shin-Cheh, Gupta, Sudeep, Lynette Ngo, Su Mien, Choong, Swee Hsia, Huang Tan, Terence Aik, Demirci, Umut, Chung, Wei-Pang, Hsieh, Wen-Son, Lu, Yen-Shen, Eralp, Yesim, Yap, Yoon Sim, Chang, Yuan-Ching, Lim, Yueh Ni
Published in Journal of clinical oncology (10.08.2024)
Published in Journal of clinical oncology (10.08.2024)
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Efficacy of avelumab + axitinib (A + Ax) versus sunitinib (S) by IMDC risk group in advanced renal cell carcinoma (aRCC): Extended follow-up results from JAVELIN Renal 101
Haanen, John B. A. G., Larkin, James, Choueiri, Toni K., Albiges, Laurence, Rini, Brian I., Atkins, Michael B., Schmidinger, Manuela, Penkov, Konstantin, Thomaidou, Despina, Wang, Jing, Mariani, Mariangela, Di Pietro, Alessandra, Motzer, Robert J.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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