Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity
Hunt, John T, Ding, Charles Z, Batorsky, Roberta, Bednarz, Mark, Bhide, Rajeev, Cho, Young, Chong, Saeho, Chao, Sam, Gullo-Brown, Johnni, Guo, Peng, Kim, Soong Hoon, Lee, Francis Y. F, Leftheris, Katerina, Miller, Arthur, Mitt, Toomas, Patel, Manorama, Penhallow, Becky A, Ricca, Carol, Rose, William C, Schmidt, Robert, Slusarchyk, William A, Vite, Gregory, Manne, Veeraswamy
Published in Journal of medicinal chemistry (05.10.2000)
Published in Journal of medicinal chemistry (05.10.2000)
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Journal Article
Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase
Ding, Charles Z, Batorsky, Roberta, Bhide, Rajeev, Chao, Hannguang J, Cho, Young, Chong, Saeho, Gullo-Brown, Johnni, Guo, Peng, Kim, Soong Hoon, Lee, Frank, Leftheris, Katerina, Miller, Arthur, Mitt, Toomas, Patel, Manorama, Penhallow, Becky A, Ricca, Carol, Rose, William C, Schmidt, Robert, Slusarchyk, William A, Vite, Gregory, Yan, Ning, Manne, Veeraswamy, Hunt, John T
Published in Journal of medicinal chemistry (16.12.1999)
Published in Journal of medicinal chemistry (16.12.1999)
Get full text
Journal Article
Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase
Ding, Charles Z, Batorsky, Roberta, Bhide, Rajeev, Chao, Hannguang J, Cho, Young, Chong, Saeho, Gullo-Brown, Johnni, Guo, Peng, Kim, Soong Hoon, Lee, Frank, Leftheris, Katerina, Miller, Arthur, Mitt, Toomas, Patel, Manorama, Penhallow, Becky A, Ricca, Carol, Rose, William C, Schmidt, Robert, Slusarchyk, William A, Vite, Gregory, Yan, Ning, Manne, Veeraswamy, Hunt, John T
Published in Journal of medicinal chemistry (16.12.1999)
Published in Journal of medicinal chemistry (16.12.1999)
Get full text
Journal Article
Discovery of ( R )-7-Cyano-2,3,4,5-tetrahydro-1-(1 H -imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1 H -1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity
Hunt, John T., Ding, Charles Z., Batorsky, Roberta, Bednarz, Mark, Bhide, Rajeev, Cho, Young, Chong, Saeho, Chao, Sam, Gullo-Brown, Johnni, Guo, Peng, Kim, Soong Hoon, Lee, Francis Y. F., Leftheris, Katerina, Miller, Arthur, Mitt, Toomas, Patel, Manorama, Penhallow, Becky A., Ricca, Carol, Rose, William C., Schmidt, Robert, Slusarchyk, William A., Vite, Gregory, Manne, Veeraswamy
Published in Journal of medicinal chemistry (01.10.2000)
Published in Journal of medicinal chemistry (01.10.2000)
Get full text
Journal Article