Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans
Mallick, Pankajini, Moreau, Marjory, Song, Gina, Efremenko, Alina Y, Pendse, Salil N, Creek, Moire R, Osimitz, Thomas G, Hines, Ronald N, Hinderliter, Paul, Clewell, Harvey J, Lake, Brian G, Yoon, Miyoung
Published in Toxicological sciences (01.01.2020)
Published in Toxicological sciences (01.01.2020)
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Journal Article
Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation
Moreau, Marjory, Mallick, Pankajini, Smeltz, Marci, Haider, Saad, Nicolas, Chantel I, Pendse, Salil N, Leonard, Jeremy A, Linakis, Matthew W, McMullen, Patrick D, Clewell, Rebecca A, Clewell, Harvey J, Yoon, Miyoung
Published in Frontiers in toxicology (29.04.2022)
Published in Frontiers in toxicology (29.04.2022)
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Journal Article
RNA-sequencing (transcriptomic) data collected in liver and lung of male and female B6C3F1 mice exposed to various dose levels of 4-methylimidazole for 2, 5, or 28 days
Black, Michael B., Andersen, Melvin E., Pendse, Salil N., Borghoff, Susan J., Streicker, Michael, McMullen, Patrick D.
Published in Data in brief (01.10.2021)
Published in Data in brief (01.10.2021)
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Journal Article
Physiologically‐based pharmacokinetic modelling to predict intragastric rifabutin concentrations in the treatment of Helicobacter pylori infection
Howden, Colin W., Shah, Shailja, Pendse, Salil N., Offman, Elliot, Almenoff, June S., Sheldon, Kely L.
Published in Alimentary pharmacology & therapeutics (01.07.2023)
Published in Alimentary pharmacology & therapeutics (01.07.2023)
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Journal Article
The Human Toxome Collaboratorium: A Shared Environment for Multi-Omic Computational Collaboration within a Consortium
Fasani, Rick A, Livi, Carolina B, Choudhury, Dipanwita R, Kleensang, Andre, Bouhifd, Mounir, Pendse, Salil N, McMullen, Patrick D, Andersen, Melvin E, Hartung, Thomas, Rosenberg, Michael
Published in Frontiers in pharmacology (2015)
Published in Frontiers in pharmacology (2015)
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Journal Article
Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity
Pendse, Salil N., Maertens, Alexandra, Rosenberg, Michael, Roy, Dipanwita, Fasani, Rick A., Vantangoli, Marguerite M., Madnick, Samantha J., Boekelheide, Kim, Fornace, Albert J., Odwin, Shelly-Ann, Yager, James D., Hartung, Thomas, Andersen, Melvin E., McMullen, Patrick D.
Published in Archives of toxicology (01.04.2017)
Published in Archives of toxicology (01.04.2017)
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Journal Article
Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates
Moreau, Marjory, Leonard, Jeremy, Phillips, Katherine A., Campbell, Jerry, Pendse, Salil N., Nicolas, Chantel, Phillips, Martin, Yoon, Miyoung, Tan, Yu-Mei, Smith, Sherrie, Pudukodu, Harish, Isaacs, Kristin, Clewell, Harvey
Published in Chemosphere (Oxford) (01.10.2017)
Published in Chemosphere (Oxford) (01.10.2017)
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Journal Article
Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods
McMullen, Patrick D., Bhattacharya, Sudin, Woods, Courtney G., Pendse, Salil N., McBride, Mary T., Soldatow, Valerie Y., Deisenroth, Chad, LeCluyse, Edward L., Clewell, Rebecca A., Andersen, Melvin E.
Published in Toxicology in vitro (01.04.2020)
Published in Toxicology in vitro (01.04.2020)
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Journal Article
Addressing systematic inconsistencies between in vitro and in vivo transcriptomic mode of action signatures
McMullen, Patrick D., Pendse, Salil N., Black, Michael B., Mansouri, Kamel, Haider, Saad, Andersen, Melvin E., Clewell, Rebecca A.
Published in Toxicology in vitro (01.08.2019)
Published in Toxicology in vitro (01.08.2019)
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Journal Article
Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures
Andersen, Melvin E., Cruzan, George, Black, Michael B., Pendse, Salil N., Dodd, Darol, Bus, James S., Sarang, Satinder S., Banton, Marcy I., Waites, Robbie, McMullen, Patrick D.
Published in Toxicology and applied pharmacology (15.11.2017)
Published in Toxicology and applied pharmacology (15.11.2017)
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Journal Article
Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids
Mallick, Pankajini, Song, Gina, Efremenko, Alina Y, Pendse, Salil N, Creek, Moire R, Osimitz, Thomas G, Hines, Ronald N, Hinderliter, Paul, Clewell, Harvey J, Lake, Brian G, Yoon, Miyoung, Moreau, Marjory
Published in Toxicological sciences (01.08.2020)
Published in Toxicological sciences (01.08.2020)
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Journal Article
Developing context appropriate toxicity testing approaches using new alternative methods (NAMs)
Andersen, Melvin E, McMullen, Patrick D, Phillips, Martin B, Yoon, Miyoung, Pendse, Salil N, Clewell, Harvey J, Hartman, Jessica K, Moreau, Marjory, Becker, Richard A, Clewell, Rebecca A
Published in ALTEX, alternatives to animal experimentation (01.01.2019)
Published in ALTEX, alternatives to animal experimentation (01.01.2019)
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Journal Article
Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver
Andersen, Melvin E., Black, Michael B., Campbell, Jerry L., Pendse, Salil N., Clewell III, Harvey J., Pottenger, Lynn H., Bus, James S., Dodd, Darol E., Kemp, Daniel C., McMullen, Patrick D.
Published in Toxicology and applied pharmacology (01.10.2017)
Published in Toxicology and applied pharmacology (01.10.2017)
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Journal Article
Strain-related differences in mouse lung gene expression over a two-year period of inhalation exposure to styrene: Relevance to human risk assessment
Andersen, Melvin E., Cruzan, George, Black, Michael B., Pendse, Salil N., Dodd, Darol E., Bus, James S., Sarang, Satinder S., Banton, Marcy I., Waites, Robbie, Layko, Debra B., McMullen, Patrick D.
Published in Regulatory toxicology and pharmacology (01.07.2018)
Published in Regulatory toxicology and pharmacology (01.07.2018)
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Journal Article
Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity
Pendse, Salil N., Maertens, Alexandra, Rosenberg, Michael, Roy, Dipanwita, Fasani, Rick A., Vantangoli, Marguerite M., Madnick, Samantha J., Boekelheide, Kim, Fornace, Albert J., Odwin, Shelly-Ann, Yager, James D., Hartung, Thomas, Andersen, Melvin E., McMullen, Patrick D.
Published in Archives of toxicology (01.04.2017)
Published in Archives of toxicology (01.04.2017)
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Journal Article
Assessing bioactivity-exposure profiles of fruit and vegetable extracts in the BioMAP profiling system
Wetmore, Barbara A., Clewell, Rebecca A., Cholewa, Brian, Parks, Bethany, Pendse, Salil N., Black, Michael B., Mansouri, Kamel, Haider, Saad, Berg, Ellen L., Judson, Richard S., Houck, Keith A., Martin, Matthew, Clewell, Harvey J., Andersen, Melvin E., Thomas, Russell S., McMullen, Patrick D.
Published in Toxicology in vitro (01.02.2019)
Published in Toxicology in vitro (01.02.2019)
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Journal Article
Editor's Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis
Foley, Briana, Doheny, Daniel L, Black, Michael B, Pendse, Salil N, Wetmore, Barbara A, Clewell, Rebecca A, Andersen, Melvin E, Deisenroth, Chad
Published in Toxicological sciences (01.01.2017)
Published in Toxicological sciences (01.01.2017)
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Journal Article
Tu1077: PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO ESTIMATE INTRAGASTRIC RIFABUTIN CONCENTRATIONS FOLLOWING RIFABUTIN 50 MG Q8H (RHB-105) OR 150 MG QD: MORE FAVORABLE EXPOSURE FOR HELICOBACTER PYLORI ERADICATON WITH Q8H DOSING
Howden, Colin W., Pendse, Salil N., Bush, Mark A., Almenoff, June S., Sheldon, Kely L.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
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Journal Article
Population Life-course exposure to health effects model (PLETHEM): An R package for PBPK modeling
Pendse, Salil N., Efremenko, Alina, Hack, C. Eric, Moreau, Marjory, Mallick, Pankajini, Dzierlenga, Michael, Nicolas, Chantel I., Yoon, Miyoung, Clewell, Harvey J., McMullen, Patrick D.
Published in Computational toxicology (01.02.2020)
Published in Computational toxicology (01.02.2020)
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